Bone invasiveness is associated with prognosis in clivus chordomas

Wang, Ke; Wang, Liang; Wu, Zhen; Tian, Kaibing; Ren, Cong; Jia, Guijun; Zhang, Liwei; Zhang, Junting

doi:10.1016/j.jocn.2015.05.073

Cited by 16 publications

(5 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…En esta serie la edad promedio fue de 55 años predominando los casos entre la sexta y séptima década de vida lo cual coincide con los estudios de P. Leah 1 y Abdul-Kareem Ahmed 10 . En la serie de casos de Raheel Ahmed 8 y Ke Wang 9 hubo un franco predominio del sexo masculino lo cual coincide con nuestra serie. La descripción sistemática de la presentación clínica de los cordomas del clivus es escasa, la cual está determinada por el tamaño de la lesión y el eje de crecimiento del mismo, sin embargo, en series de casos reportan cefalea, disturbios visuales, parálisis del VI nervio craneal, defecto motor, dolor cervical, trastornos neuroendocrinos entre otros 2 ; nuestros resultados mostraron similitud con estas series siendo la cefalea y la parálisis del VI nervio craneal las que más prevalecieron.…”

Section: Discussionunclassified

See 1 more Smart Citation

Cordomas del clivus. Consideraciones del tratamiento quirúrgico endoscópico

et al. 2021

View full text Add to dashboard Cite

Introducción: Los cordomas del clivus son neoplasias de lento crecimiento, originadas de restos de la notocorda, que invaden el hueso y tienen alto índice de recurrencia. Objetivo: Caracterizar el comportamiento de esta entidad en nuestro centro en cuanto a los aspectos clínicos, radiológicos, terapéuticos y evolutivos. Método: Se realizó un estudio descriptivo retrospectivo en el período comprendido entre enero de 2010 a diciembre de 2015. La muestra fue de 10 pacientes, 6 masculinos y 4 femeninos, con una edad promedio de 55 años. Se realizó en todos los casos un abordaje endonasal endoscópico extendido al clivus, seguido de radioterapia de intensidad modulada (IMRT) hipofraccionada o 3D conformada Resultados: Las alteraciones clínicas más frecuentes fueron: la cefalea y la diplopía. Predominaron los cordomas clásicos al final de la sexta década de vida y en el sexo masculino. Se logró una resección completa de la lesión en el 80% de los casos y un control de la enfermedad a los 4 años en el 90%. Existieron aceptables complicaciones y un fallecido que presentó fístula del líquido cefalorraquídeo y meningitis. Conclusiones: El abordaje endonasal endoscópico extendido al clivus constituye una opción quirúrgica excelente y prometedora, lográndose una resección quirúrgica radical de la lesión con aceptables complicaciones.

show abstract

Section: Discussionunclassified

“…La supervivencia libre de enfermedad está en dependencia del grado de resección de la lesión, el tipo histológico, el tamaño de la lesión y el tipo de radioterapia empleada 8,9 . Las complicaciones quirúrgicas más comunes son la parálisis de nervios craneales, seguido de la fistula del líquido cefalorraquídeo, meningitis y hematomas.…”

Section: Introductionunclassified

Cordomas del clivus. Consideraciones del tratamiento quirúrgico endoscópico

et al. 2021

View full text Add to dashboard Cite

show abstract

“…The lesions at the inferior clivus pose a surgical challenge with high morbidity and mortalityto neurosurgeons because ofthe critical neurovascular structures surrounding the lesion [1][2][3][4].Many studies have described the far-lateral approach which exposed theinferior clivus superior to the anterior edge of foramen magnum [5][6][7][8]. The concern of neurovascular protection and skull base reconstruction promotes the development of surgical anatomy for the far-lateral approach [9][10][11].…”

Section: Introductionmentioning

confidence: 99%

Volumetric Comparative Analysis of Anatomy Through Far-Lateral Approach: Surgical Space and Exposed Tissues

Tang

Xu²,

Yuan

et al. 2021

Preprint

View full text Add to dashboard Cite

Objective The three-dimensional (3D) visualization model has ability to quantify the surgical anatomy of far-lateral approach. This study was designed to disclose the relationship between surgical space and exposed tissues in the far-lateral approach by the volumetric analysis of 3D model. Methods The 3D skull base modelswere constructed using MRI and CT data of 15 patients (30 sides) with trigeminal neuralgia. Surgical corridorsof the far-lateral approach was simulated by triangular pyramids to represent two surgical spaces exposing bony and neurovascular tissues. Volumetric comparison of surgical anatomy was performed using pair t test. Results The morphometric results were almost the same in the two surgical spaces except the vagus nerve (CN X) exposed only in one corridor. Whereas, the volumetric comparison represented the statistical significant differences of surgical space, and bony and neurovascular tissues involved in the two corridors (P༜0.001). The differences of bony and neurovascular tissuesfailed to equal the difference of surgical space. Conclusions For far-laterl approach, the increase of exposure for the bony and neurovascular tissues is not necessarilymatched with the increase of surgical space. The volumetric comparative analysis is helpful to provide more detailed anatomical information in the surgical design.

show abstract

Section: Introductionmentioning

confidence: 99%

Volumetric comparative analysis of anatomy through far-lateral approach: surgical space and exposed tissues

Tang¹,

Xing²,

Yuan³

et al. 2021

Preprint

View full text Add to dashboard Cite

Background The three-dimensional (3D) visualization model has ability to quantify the surgical anatomy of far-lateral approach. This study was designed to disclose the relationship between surgical space and exposed tissues in the far-lateral approach by the volumetric analysis of 3D model. Methods The 3D skull base models were constructed using MRI and CT data of 15 patients (30 sides) with trigeminal neuralgia. Surgical corridors of the far-lateral approach was simulated by triangular pyramids to represent two surgical spaces exposing bony and neurovascular tissues. Volumetric comparison of surgical anatomy was performed using pair t test. Results The morphometric results were almost the same in the two surgical spaces except the vagus nerve (CN X) exposed only in one corridor. Whereas, the volumetric comparison represented the statistical significant differences of surgical space, and bony and neurovascular tissues involved in the two corridors (P༜0.001). The differences of bony and neurovascular tissuesfailed to equal the difference of surgical space. Conclusions For far-laterl approach, the increase of exposure for the bony and neurovascular tissues is not necessarilymatched with the increase of surgical space. The volumetric comparative analysis is helpful to provide more detailed anatomical information in the surgical design.

show abstract

Bone invasiveness is associated with prognosis in clivus chordomas

Cited by 16 publications

References 30 publications

Cordomas del clivus. Consideraciones del tratamiento quirúrgico endoscópico

Cordomas del clivus. Consideraciones del tratamiento quirúrgico endoscópico

Volumetric Comparative Analysis of Anatomy Through Far-Lateral Approach: Surgical Space and Exposed Tissues

Volumetric comparative analysis of anatomy through far-lateral approach: surgical space and exposed tissues

Contact Info

Product

Resources

About