Body mass index and lipid levels in children from Ankara, Turkey versus Bogalusa, Louisiana

Ağırbaşlı, Mehmet; Ciliv, G; Cakir, Servet; Srinivasan, Sathanur R.; Berenson, Gerald S.; Özme, Şencan

doi:10.1016/j.ypmed.2005.08.001

Cited by 15 publications

(17 citation statements)

References 11 publications

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“…Despite their lower BMI, Turkish children paradoxically displayed higher triglyceride and lower HDL-C levels [39]. African American children and adolescents had higher prevalence of obesity and high blood pressure compared to their white counterparts.…”

Section: Ethnic and Population Contrastsmentioning

confidence: 94%

“…Children and adolescents with persistent low HDL-C and with low HDL-C that normalize by adulthood have an increased risk of high cIMT [13]. Low HDL-C levels may become a major concern particularly for developing countries [39]. Thus, non-HDL cholesterol and Apo B are likely to be better parameters than LDL-C to assess cardiometabolic risk among children [40].…”

Section: Screening For Dyslipidemia In Childrenmentioning

confidence: 99%

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Metabolic Syndrome: Bridging the Gap from Childhood to Adulthood

Ağırbaşlı

Tanrikulu

Berenson

2016

Cardiovascular Therapeutics

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SUMMARYChildhood and adolescence are particularly vulnerable periods of life to the effects of cardiometabolic risk and later development of atherosclerosis, hypertension, and diabetes mellitus. Developing countries with limited resources suffer most heavily from the consequences of cardiometabolic risk in children and its future implications to the global health burden. A better understanding of mechanisms leading to cardiometabolic risk in early life may lead to more effective prevention and intervention strategies to reduce metabolic stress in children and later disease. Longitudinal "tracking" studies of cardiometabolic risk in children provide a tremendous global resource to direct prevention strategies for cardiovascular disease. In this review, we will summarize the pathophysiology, existing definitions for cardiometabolic risk components in children. Screening and identifying children and adolescents of high cardiometabolic risk and encouraging them and their families through healthy lifestyle changes should be implemented to as a global public health strategy.

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Section: Ethnic and Population Contrastsmentioning

confidence: 94%

Section: Screening For Dyslipidemia In Childrenmentioning

confidence: 99%

Metabolic Syndrome: Bridging the Gap from Childhood to Adulthood

Ağırbaşlı

Tanrikulu

Berenson

2016

Cardiovascular Therapeutics

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“…14,15 Risk factors such as high blood pressure, parental smoking are common among Turkish children and adolescents 16 and cardiovascular risk profile in Turkish children appear to be unique compared to different populations. 17 In this study, we examined temporal trends in body mass index (BMI), parental smoking and blood pressure by comparing 15-17 years old children in [1989][1990] and in [2004][2005].…”

Section: Introductionmentioning

confidence: 99%

Trends in body mass index, blood pressure and parental smoking habits in middle socio-economic level Turkish adolescents

et al. 2007

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Patterns of cardiovascular risk factors in populations are not static over time. We examined trends in body mass index (BMI), parental smoking and blood pressure over a 15-year period in Turkish children aged 15-17 years. Two cross-sectional studies were performed in secondary schools in Turkey in 1989-1990 and 2004-2005. Study participants were 673 children in 1989-1990 and 640 adolescents in 2004-2005. Main outcome measures were weight, height, BMI, presence and amount of parental smoking, systolic and diastolic blood pressure. Age and sex matched comparisons were performed to assess temporal trends in these measures. Children in 2004-2005 had increased weight, height, BMI and decreased systolic and diastolic blood pressure in all age groups compared with children in [1989][1990]. According to the international criteria, 3.4% of children were obese and 15.8% were overweight in 2005, compared to 0.7% obese and 4.2% overweight in 1990 (Po0.001). However, a decrease was noted in blood pressure; 16% were classified as hypertensive in 1989 -1990 versus 8% in 2004. The prevalence and amount of parental smoking also decreased over the last 15 years. We observed significant changes in BMI and blood pressure in Turkish children over the last 15 years. Temporal trends in these parameters may indicate a change in the pattern of cardiovascular disease in this population.

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“…Otra variable importante y determinante en el nivel de lípidos y hormonas es el IMC. Varios estudios han demostrado que esta variable conserva una relación directa con el colesterol total e una inversa con las HDL (35). En este trabajo, las niñas entre 11 y 18 años tienen un índice de masa corporal significativamente mayor que los niños de la misma edad y también el colesterol total, lo que prueba esta relación.…”

Section: Discussionunclassified

Diferencias de sexo, edad y lípidos plasmáticos asociadas al polimorfismo de la apolipoproteína E en un grupo de escolares de Quindío, Colombia

et al. 2009

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Introducción. El polimorfismo de la apolipoproteína E (apoE) es un factor determinante genético de los niveles de colesterol total y colesterol LDL. Objetivo. Evaluar la relación del polimorfismo apoE con el perfil lipídico por edad y sexo en escolares quindianos de 8 a18 años. Materiales y métodos. Se utilizó la reacción en cadena de la polimerasa y enzimas de restricción para la genotipificación de apoE en 500 escolares de 8 a 18 años. Los lípidos sanguíneos se determinaron con estuches comerciales. Resultados. La frecuencia alélica fue: E3 (91,6%), E2 (5,3%) y E4 (3,1%); y la frecuencia genotípica: E3/E3 (90,8%), E2/E3 (5,6%) y E3/E4 (3,2%). No se encontraron homocigotos para E2/E2 y E4/E4. Se encontraron distribución genotípica y alélica similares para cada sexo. El genotipo apoE y el sexo tuvieron un efecto significativo sobre el colesterol total y el colesterol LDL. En niños, ambas variables se distribuyeron así: E4>E3>E2 (p<0,05); en niñas: E3>E4>E2; el colesterol LDL en niños fue: E2>E4>E3; y, en niñas: E4>E2>E3. En niños, el alelo con efecto protector fue el E2, en todas las variables; mientras que, en las niñas, este alelo fue protector sólo para el colesterol total y colesterol LDL; para triacilglicéridos y colesterol VLDL y altos niveles de colesterol LDL, el efecto protector estuvo en el E4 (p<0,05). Conclusión. Estos resultados sugieren una asociación entre el genotipo apoE y los lípidos plasmáticos de la población estudiada, influenciada por sexo y edad, especialmente, en niñas mayores de 10 años. Sin embargo, se necesita ampliar la población.Palabras clave: polimorfismo genético, apolipoproteínas E, lípidos, colesterol, triglicéridos, polimorfismo, hormonas, niño, adolescente. Gender, age and plasma lipids differences associated with apolipoprotein E polymorphism in school childrenIntroduction. Apolipoprotein E (apoE) polymorphism is a genetic determinant of total cholesterol and LDL-c levels. Several studies have examined the relationship between variations at the APO E and cardiovascular disease. It is important to determine this relationship in the Colombian population. Objectives. The relationship of apoE polymorphisms was associated with lipid profile by age and sex. Materials and methods. A sample of 500 children aged 8 to 18 years, were selected from school populations in Quindio Province, Colombia. ApoE genotypes were determined by polymerase chain reaction and restriction enzyme. Lipid profiles were obtained by commercial kits. Results. The apoE allele frequencies were as follows: E3 -91.6%, E2 -5.3, and E4 -3.1%. Genotypic frequencies were as follows: E3/E3 -90.8%, E2/E3 -5.6%, and E3/E4 -3.2%. No homozygotes for E2/E2 and E4/E4 were recovered. Similar genotypic and allelic distribution was found for each gender. ApoE genotype and gender had a significant effect on total serum cholesterol (CT) and low density lipoprotein cholesterol (c-LDL). In boys these variables were related as follows: E4>E3>E2 (p<0.05); in girls the relationships were somewhat changed

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Body mass index and lipid levels in children from Ankara, Turkey versus Bogalusa, Louisiana

Cited by 15 publications

References 11 publications

Metabolic Syndrome: Bridging the Gap from Childhood to Adulthood

Metabolic Syndrome: Bridging the Gap from Childhood to Adulthood

Trends in body mass index, blood pressure and parental smoking habits in middle socio-economic level Turkish adolescents

Diferencias de sexo, edad y lípidos plasmáticos asociadas al polimorfismo de la apolipoproteína E en un grupo de escolares de Quindío, Colombia

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