Body mass characteristics of hip osteoarthritis patients experiencing aseptic loosening, periprosthetic fractures, dislocation, and infections after total hip replacement

Abstract

This work assessed the body mass characteristics of a cohort of community dwelling adults requiring surgery for complications related to primary hip arthroplasty, among other factors. The specific aim was to identify the extent to which high body mass prevailed in the cohort as a whole, to identify a role for subnormal body mass in the pathogenesis of post-operative complications following hip joint arthroplasty, and to identify whether different complication types could be differentiated on the basis of body mass profiles. The subjects were males and females drawn from a representative sample of 1,040 hip osteoarthritis patients between the ages of 30–89 years hospitalized for purposes of primary hip arthroplasty or complications related to prior replacement surgery. An analysis of their medical records showed: 1) Approximately 20% of the present cohort was constituted by patients with various complications related to prior arthroplasties, or to general deterioration of their condition; 2) The most common reasons for their re-hospitalization were aseptic prosthetic loosening followed by infection, prosthetic dislocations, prosthetic and periprosthetic fractures, and second surgeries on the opposite hip; 3) The presence of a high body mass index differentiated those presenting with aseptic prosthetic loosening, periprosthetic fractures, and those with infected hips (p < 0.007). Those with infection diagnoses were significantly heavier on average than those with no infection, regardless of diagnosis, and more cases with a dislocation history were underweight, rather than overweight (p < 0.05). It is concluded, a small but clinically relevant proportion of obese or underweight adults with hip osteoarthritis who undergo primary total hip replacement may experience complications at higher rates than cases with normal body weight, despite the generally successful outcomes experienced by the majority of hip arthroplasty patients.

Total hip and knee arthoplasty: on the issue of indications for surgery

“…Этот вид осложнения чаще отмечается при бесцементной фиксации импланта, то есть при хирургическом лечении пациентов младше 60 лет [27]. Кроме того, при ревизионной артропластике ТБС переломы бедрен ной кости при цементной фиксации происходят в 3-6,3 % случаев, а при бесцементной замене сустава -в 17,6-46 % [28,29].…”

“…Инфекция области хирургического вмешательства -самый частый неблагоприятный исход эндо протезирования ТБС и КС [28,30,31]. Случаи инфекции области хирургического вмешательства при артропластике ТБС зафиксированы в 1-8 % наблюдений [32,33].…”

Nano Sized Gallium Oxide Surface Features for Enhanced Antimicrobial and Osteo-Integrative Responses

“…[5][6][7] Overall failure occurs in about 10-30% of patients and depends on genetic or health factors and is predicted to increase into the future as life expectancy improves. [8][9][10].…”

A Comparative Analysis on Adaptation Behavior and Failure Risk of Femurs of Different Qualities Under the Effect of Direct Transfemoral Fixations

“…According to Wolf's law, changes in the mechanical loading environment leads to internal (density) and external (shape) bone adaptation (WOLFF and J 1892). Furthermore, reduction of periprosthetic bone mineral density (BMD) may lead to complications such as aseptic loosening, infection, and fractures (Electricwala et al 2016;Marks 2009). Hence, several empirical studies have been conducted to monitor the periprosthetic bone remodeling around osseointegrated trans-femoral prostheses (Nebergall et al 2012;Thomson et al 2019).…”