Background. Both in Russia and across the world, the annual frequency of total hip and knee replacement has increased, which has inevitably led to an increase in the number of patients with unsatisfactory treatment outcomes. This failure can primarily be attributed to the complications that arise, some of which arise due to the wrong choice of treatment approach. Aim. To analyze the publications on the results of treatment of patients with hip osteoarthritis and knee osteoarthritis by total hip and knee replacements. Materials and methods. The literature data were searched in open electronic databases of scientific literature PubMed and eLibrary using the following keywords and phrases: total hip/knee replacement, complications, patient satisfaction, age, obesity. The search depth was 20 years. Results. The data indicated a rise in the total number of such patients recorded annually. A significant number of publications, both in Russian and foreign literature, are devoted to the analysis of complications that mainly determine the patients satisfaction with an operation. In addition, these articles analyze the issues of determining the indications and contraindications in applying these methods of treatment. However, it is not uncommon for orthopedists to form a decision for performing an operation based on their subjective experience. At the same time, one of the circumstances that influences the decision-making is the lack of a stable system in the conservative treatment of degenerative joint diseases. According to the data from health care organizations, hip and knee replacements are the only available method for treating osteoarthritis. This circumstance may lead to an unjustified expansion of indications for arthroplasty, which would definitely affect the outcomes of treatment. In this situation, it is critical to search for precise criteria to identify the indication for total hip and knee arthroplasty. Conclusion. Unjustified expansion of indications for endoprosthesis leads to an increase in the number of complications, which in turn leads to an increase in the number of patients who remain unsatisfied with the outcomes of hip and knee arthroplasty in the long term. This circumstance encourages special scientific research to clarify the indications and contraindications for hip and knee replacements, especially in young and middle-aged people.
Abstract. Introduction The study deals with the approaches to the analysis of the dynamics in the course of a long-term postoperative period in patients who underwent hip arthroplasty. Aim To feature the variants in the course of a long-term postoperative period in patients who underwent arthroplasty of the hip joint. Materials and methods 806 patients (age range, 9 to 88 years) suffering from osteoarthritis underwent primary total hip arthroplasty (THA). Statistical analysis was carried out using the R programming language, freely available at https://cran.r-project.org. The probability of maintaining satisfactory quality of life (QoL) at a certain time of observation t (year of observation) was assessed with the Kaplan-Meier method. To compare the likelihood of maintaining a satisfactory QoL level throughout the observation period in several groups (for example, patients of different sexes), the logrank test was used. Results By year 6 of follow-up, the following tendency emerges regarding the age of the patients. The indicators are the best in young patients (up to 44 years old), where the probability of maintaining a satisfactory QoL evaluation was 0.92 (0.84; 0.96). A somewhat lower values were observed in the patients of the middle age group (from 45 to 64 years old) – 0.87 (0.78; 0.92). Excellent and good QoL was found in patients aged 65 and older, 0.83 (0.76; 0.88). Discussion Survival analysis methods have been used for the first time in traumatology and orthopedics. Previous researchers assessed the long-term results of the quality of specialized traumatological and orthopedic care without considering censored observations. Thus, the coverage of the investigated clinical observations averaged 80-85%. Information about 10-15% of cases was excluded from the studies. The proposed method of analysis provides information about all patients. Conclusions Five years following THA, an excellent and good quality of life could be expected in 85 % of patients. Satisfactory and poor levels are observed in 15 % of patients. At 5-year follow-up after THA, the quality of life is worse in older female groups with severe concomitant pathology; however, there are no statistically significant differences. This is a tendency, and requires further study.
Abstract. Introduction Periprosthetic infection in hip arthroplasty is a social and economic problem. Its main reason is multidrug resistance of microorganisms. Purpose To evaluate the effectiveness of the first stage in two-stage revision arthroplasty for the treatment of deep periprosthetic infection of the hip joint by improving the constructive and antibacterial features of spacers. Materials and methods The treatment results of 127 patients with late deep periprosthetic hip joint infection who underwent two-stage revision arthroplasty in the period from 2015 to 2019 were analyzed. In the first group, 42 patients were fitted with a two-component (total) spacer based on the developed antimicrobial composition of bone cement with gentamicin, antiseptics and polymer (patent RU 191236). In the second group, a two-component spacer (patent RU 174697) based on conventional bone cement with gentamicin was implanted in 43 patients; the third group of 42 patients had a preformed spacer. Results A bactericidal and antiadhesive, nontoxic composition based on bone cement with gentamicin with antiseptics poviargol, dioxidine and high molecular weight polyvinylpyrrolidone with a prolonged action for 348 days against gentamicin-resistant staphylococci has been developed. All patients underwent the first stage of hip arthroplasty with removal of the implant and installation of a spacer. Recurrence of periprosthetic infection was observed in 1 (2.3 %) patient of the first group, in 5 (11.6 %) in the second and in 6 (14.2 %) patients of the third group. Non-infectious complications such as spacer dislocation and instability were observed in 12 cases, one case (2.3 %) in the first, 2 (4.6 %) in the second and 9 (21.4 %) in the third group. The average time from the first stage of treatment to the second stage of re-implantation was 7.5 months (range, 4–13 months). Discussion According to the literature, the introduction of new antibiotics into the bone cement with gentamicin does not increase the antimicrobial action of the spacer, especially against antibiotic-resistant isolates, and the use of a preformed spacer contributes to an increase in the number of non-infectious complications. Antiseptics with different mechanisms of action are able to act on antibiotic-resistant bacteria, and the polymer can prolong this effect. Conclusions Creation of two-component spacers based on bone cement with gentamicin using antiseptics with different mechanisms of action and polymer promotes long-term bactericidal action of the spacer, which leads to effective sanation of the joint area, reducing non-infectious complications.
1707 Total Hip and Knee Arthroplasty had been retrospectively analyzed for the research. All patients’ data (non-complicated post- Hip and Knee Arthroplasty (1st group - 1579 patients) and post- Hip and Knee Arthroplasty with surgical site infection in 12 months (2nd group - 128 patients)) had been used as an educational matrix for a mathematic forecast and as a construction of a prevention algorithm for septic complications in primary THA and TKA. The study had shown 14 significant criteria which can influence the occurrence of surgical site infection in THA and TKA. 12-month testing period of the software in prospective research (467 cases) had shown a significant decrease rate of surgical site infection in comparison to retrospective research (decrease of 7.5% in the prospective cases and 4.1% - in retrospective).
A significant role in the pathogenesis of osteoarthritis (OA) belongs to the violation of the natural bioelectrogenesis of bone and cartilage tissue. External correction of bioelectric processes in joint structures by means of an electrostatic electret field is pathogenetically justified and has practical significance in the surgical treatment of degenerative diseases in orthopedics. The article presents an analysis of the results of surgical treatment in 45 patients with stage 2-3 gonarthrosis aged 30 to 70 years using electretes based on tantalum oxide. The results of treatment were evaluated based on the dynamics of the clinical and functional index WOMAC, data from clinical and radiological studies. The positive effect of the electrostatic field of electret in OA was manifested by a decrease in clinical symptoms of the disease, increased functional activity of patients, restraining degenerative changes in joint structures, and improving the quality of daily life during the follow-up period. The positive effect of the electrostatic field of electret is based on the activation of repair of bone-cartilage structures, which allowed to slow down the degradation of subchondral bone and articular cartilage in gonarthrosis.Clinical use of electret stimulators significantly effectively improves joint function which reduces the risk of progression of degenerative changes in the joint especially in patients with the second stage of the disease. The clinical use of electronic stimulators significantly effectively improves joint function which reduces the risk of progression of degenerative changes in the joint especially in patients with the second stage of the disease.The use of electretes in the treatment of patients with stage 3 gonarthrosis can improve the function of the joint for a long time more (2 years) and postpone the endoprosthesis operation.
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