Body Dysmorphic Disorder in Patients With Obsessive-Compulsive Disorder: Prevalence and Clinical Correlates

Costa, Diogo; Assunção, Melissa Chagas; Ferrão, Ygor Arzeno; Conrado, Luciana Archetti; Gonzalez, Christina Hajaj; Fontenelle, Leonardo F.; Fossaluza, Victor; Miguel, Eurí­pedes Constantino; Torres, Albina Rodrigues; Shavitt, Roseli Gedanke

doi:10.1002/da.21980

Cited by 40 publications

(33 citation statements)

References 69 publications

(151 reference statements)

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“…Specifically, our results suggest that a preoccupation with one's bodily appearance may have a causal influence that produces the manifestation of HA‐related fears. There is some clinical evidence to suggest a specific overlap between BDD and HA . Conceptually, this result also appears to align with the classification of HA together with BDD/OCD in the OCRDs chapter of ICD‐11.…”

Section: Discussionsupporting

confidence: 68%

Predictors and consequences of health anxiety symptoms: a novel twin modeling study

López-Solà

Bui

Hopper

et al. 2018

Acta Psychiatr Scand

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Section: Discussionsupporting

confidence: 68%

Predictors and consequences of health anxiety symptoms: a novel twin modeling study

López-Solà

Bui

Hopper

et al. 2018

Acta Psychiatr Scand

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“…Poor insight in OCD has been associated with early age of onset (Catapano et al, 2010), intense symptom severity (Storch et al, 2008, Catapano et al, 2010), co-morbidity with schizotypal personality disorder and body dysmorphic disorder (Catapano et al, 2010, Costa et al, 2012), unfavorable responses to behavioral and pharmacological interventions (Erzegovesi et al, 2001, Himle et al, 2006), and poor prognosis (Matsunaga et al, 2002, Catapano et al, 2010). Furthermore, relative to their counterparts with good insight, OCD patients with poor insight have been reported to have more severe neuropsychological deficits in conflict resolution/response inhibition and verbal memory (Tumkaya et al, 2009, Kashyap et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Resting-state functional connectivity between right anterior insula and right orbital frontal cortex correlate with insight level in obsessive-compulsive disorder

Fan

Zhong

Lee

et al. 2017

NeuroImage: Clinical

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Few studies have explored the neurobiological basis of insight level in obsessive-compulsive disorder (OCD), though the salience network (SN) has been implicated in insight deficits in schizophrenia. This study was then designed to investigate whether resting-state (rs) functional connectivity (FC) of SN was associated with insight level in OCD patients. We analyzed rs-functional magnetic resonance imaging (fMRI) data from 21 OCD patients with good insight (OCD-GI), 19 OCD patients with poor insight (OCD-PI), and 24 healthy controls (HCs). Seed-based whole-brain FC and ROI (region of interest)-wise connectivity analyses were performed with seeds/ROIs in the bilateral anterior insula (AI) and dorsal anterior cingulate cortex (dACC). The right AI-right medial orbital frontal cortex (mOFC) connectivity was found to be uniquely decreased in the OCD-PI group, and the value of this aberrant connectivity correlated with insight level in OCD patients. In addition, we found that the OCD-GI group had significantly increased right AI-left dACC connectivity within the SN, relative to HCs (overall trend for groups: OCD-GI > OCD-PI > HC). Our findings suggest that abnormal right AI-right mOFC FC may mediate insight deficits in OCD, perhaps due to impaired encoding and integration of self-evaluative information about OCD-related beliefs and behaviors. Our findings indicate a SN connectivity dissociation between OCD-GI and OCD-PI patients and support the notion of considering OCD-GI and OCD-PI as two distinct disorder subtypes.

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“…Su prevalencia en muestras comunitarias oscila entre 0,7% y 2,5% 3,6 , y hasta 12% en pacientes obsesivo-compulsivos 7 , siendo elevada también en consultantes dermatológicos y de cirugía plástica 3 . Por otra parte, un estudio determinó que 32% de los sujetos con TDC padecía un TCA comórbido 8 , mientras que en una exploración de pacientes con TCA se verificó una frecuencia de 45% para TDC 9 .…”

Section: Epidemiologíaunclassified

“…En esta línea, Conceição et al detectaron que individuos con TDC comórbido a un trastorno obsesivo-compulsivo presentaron mayores tasas de conductas suicidas y desórdenes del ánimo, alimentarios, por excoriación, ansiedad, hipocondriasis y síndrome de la Tourette. Adicionalmente, el inicio sintomático obsesivo-compulsivo fue precoz, más severo y con menor introspección 7 .…”

Section: (F5002) Tipo Con Atracones/purgas: Durante Los úLtimos Tresunclassified

Trastorno dismórfico corporal: aspectos clínicos, dimensiones nosológicas y controversias con la anorexia nerviosa

et al. 2016

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Body dysmorphic disorder: clinical aspects, nosological dimensions and controversies with anorexia nervosa There is strong evidence about the co-existence of body dysmorphic disorder (BDD) and eating disorders (ED), particularly with anorexia nervosa (ANL as distorsiones cognitivas respecto de la apariencia son centrales en el trastorno dismórfico corporal (TDC), cuyos portadores demuestran preocupación por defectos físicos imaginarios, leves o aún invisibles a los demás y en algunos casos próximos a una condición delirante, que se gestaría desde la idea sobrevalorada, con una alta ponderación de las creencias individuales, surgidas a partir de fuertes sentimientos en torno a defectos auto-percibidos que eclipsan la introspección cognitivo-racional. La entidad parece ser relativamente común en la población general y en contextos psiquiátricos, dermatológicos y de cirugía cosmética 1 . La relación entre el TDC y los trastornos de la conducta alimentaria (TCA) se expresa principalmente en la anorexia nerviosa (AN), mas su intercurrencia ha sido escasamente investigada y diagnosticada 2 , traduciéndose en una severa discapacidad psicosocial, con deficiente calidad de vida e incluso alto riesgo suicida 3 . La etiología precisa del TDC es desconocida, pero se plantea un considerable componente hereditario, pues el trastorno se presenta hasta ocho veces más frecuentemente en las familias con antecedentes de la patología. Se han verificado anormalidades en la función ejecutiva, el reconocimiento emocional y la auto-percepción visual, siendo la serotonina un modulador conductualmente relevante 4 .

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Body Dysmorphic Disorder in Patients With Obsessive-Compulsive Disorder: Prevalence and Clinical Correlates

Abstract: Because OCD patients might not inform clinicians about concerns regarding their appearance, it is essential to investigate symptoms of BDD, especially in young patients with early onset and comorbid social anxiety, chronic depression, skin picking, or eating disorders.

Cited by 40 publications

References 69 publications

Predictors and consequences of health anxiety symptoms: a novel twin modeling study

Predictors and consequences of health anxiety symptoms: a novel twin modeling study

Resting-state functional connectivity between right anterior insula and right orbital frontal cortex correlate with insight level in obsessive-compulsive disorder

Trastorno dismórfico corporal: aspectos clínicos, dimensiones nosológicas y controversias con la anorexia nerviosa

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