BODIPY-based fluorometric sensor array for the highly sensitive identification of heavy-metal ions

Zinc(II) and pyrophosphate selective fluorescence probe and its application to living cell imaging

“…Synthesis of chemosensor 1 [27] N,N-di(pyridin-2-ylmethyl)-ethane-1,2-diamine (DPEN) (336 mg, 1.0 mmol) and triethylamine (140 L, 1 mmol) were dissolved in 15 mL dichloromethane and followed by addition of 3,5-dichloroBODIPY (242 mg, 1.0 mmol). The mixture was stirred at room temperature for 1 h. The solvent was removed under reduced pressure and the residue was extracted with dichloromethane (30 mL ×3).…”

Synthesis and Optical Properties of meso‐CF3‐BODIPY with Acylethynyl Substituents in the 3‐Position of the Indacene Core

“…Conversely, a lot of reports concerning meso ‐alkyl and ‐aryl symmetric and asymmetric ethynyl‐substituted BODIPY compounds have been published in recent years. Ethynylated BODIPYs have been used as selective colorimetric and fluorescent chemodosimeters for fluoride ions, highly sensitive and selective sensors for the cations of Cu 2+ , Hg 2+ , and other heavy metals . They are also prospective drugs against human carcinoma HEp2 .…”

Optical sensor: a promising strategy for environmental and biomedical monitoring of ionic species

“…[309][310][311][312] Contrary to these structural and functional applications, a high level of zinc is cytotoxic and may lead to skin disease, diabetes, prostatic adenocarcinoma and pancreatic islets could play critical roles in insulin biosynthesis, storage, and secretion. 317 Therefore, the subcellular Zn 2+ imaging using fluorescence sensors in the specific compartments alongside distinct intracellular distribution patterns is of great interest. 315 Research into zinc recognition has expanded in recent decades to encompass many areas of chemistry; from small molecule sensors to peptidebased systems and elaborate supramolecular complexes.…”