Blood Serum Fatty Acid Patterns of Adolescent Boys as Influenced by Source of Dietary Fat: Corn Oil/Butter Oil, Safflower Oil/Beef Tallow

Kies, Constance; Lin, L.; Fox, Hazel M.; Korslund, Mary K.

doi:10.1111/j.1365-2621.1978.tb02362.x

Cited by 3 publications

(2 citation statements)

References 9 publications

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“…The concentration of cholesterol in HDL was measured after the precipitation of low and very low density lipoproteins by heparin-MnCl 2 . 27 Reproducibility for blind control sera as obtained in the Center for Disease Control Survey of HDL-measurements 28 was within ± 2.2% and this, with regard to the overall survey mean, was an average of 0-1%. Blood samples were taken scattered over the day.…”

mentioning

confidence: 85%

Serum HDL/total cholesterol ratio and blood pressure in asymptomatic atherosclerotic lesions of the cervical carotid arteries in men.

Merode¹,

Hick²,

Hoeks³

et al. 1985

Stroke

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One hundred neurologically asymptomatic male subjects (aged 50-69 years), randomly selected through population registers, were screened for atherosclerotic lesions of the cervical carotid arteries, using a high resolution multi-gate pulsed Doppler system. In 93 subjects serum was assayed for total and HDL cholesterol. Besides, cuff arterial blood pressure measurements were made. Twenty-three of these subjects (Group III) were classified as abnormal according to the Doppler investigation (degree of narrowing less than 50% in 78% of the cases). Seven of these 23 subjects also had a history of ischemic heart disease or intermittent claudication. Of the 70 subjects with a normal Doppler examination 16 had a history of ischemic heart disease and/or intermittent claudication (Group II). The remaining 54 subjects served as controls (Group I). The frequency of asymptomatic atherosclerotic lesions of the cervical carotid arteries in the population under investigation was 23%. The HDL/total cholesterol ratio was lower and the frequency of high blood pressure higher in the Groups II and III than in Group I. The findings in this study support the idea that a low serum HDL/total cholesterol ratio and high blood pressure have a high degree of association with atherosclerotic lesions of the cervical carotid arteries. This association is already apparent at an early stage of the disease, i.e. in asymptomatic subjects with a slight to moderate degree of carotid artery narrowing.

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mentioning

confidence: 85%

Serum HDL/total cholesterol ratio and blood pressure in asymptomatic atherosclerotic lesions of the cervical carotid arteries in men.

Merode¹,

Hick²,

Hoeks³

et al. 1985

Stroke

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“…Therefore we applied both the direct method and the Abell method to sara of normolipemic subjects who had participated in a trial of diets either low or high in linoleic acid (8). These diets represented extremes of what can be achieved with commonly available foodstuffs andmust have caused marked differences in serum cholesterol ester fatty acid composition within a few weeks (13,14). In 15 subjects who for five weeks ate a natural diet that provided 40% of energy as fat, 19% as cis-cis linoleic acid, and had a polyunsaturated:saturated fat (P:S) ratio of 1.7, the serum cholesterol concentration according to the direct method was 1.5 ± 0.9% (mean ± SEM) higher than the concentration determined by the Abell method.…”

Section: Interference Due To Cholesterol Ester Fatty Acid Compositionmentioning

confidence: 99%

Standardization of serum cholesterol assays by use of serum calibrators and direct addition of Liebermann-Burchard reagent.

Katan¹,

Haar²,

Kromhout³

et al. 1982

Clinical Chemistry

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Serum cholesterol concentrations of subjects in epidemiological studies were measured after direct addition of Liebermann-Burchard reagent; results were calibrated with human serum pools assayed according to Abell et al. (J. Biol. Chem. 195:357-366, 1952). Accuracy and precision were monitored for six years by analysis of internal-control pools and blind external-control pools. For various internal-control pools, the imprecision (CV) of the long-term averages of run means ranged from 0.5 to 0.9%. The within-run CV for internal control and patients' sera was about 1%. For blind control sera with different concentrations (provided by the Centers for Disease Control, Atlanta, GA, over the same period), the average difference per three-month period between the values found and the target values was usually between -0.5% and +0.7% for medium-concentration pools and between -2% and +2% for low- and high-concentration pools (extreme values: -2.4% and +2.5%). The CV per three-month period ranged from 0.6 to 2.7%. Sera from subjects on diets of high or low linoleic acid content were analyzed to study the effect of the fatty acid portion of serum cholesterol esters; the differences between values obtained with the comparison method and the direct method was insignificant on both diets. We conclude that the use of serum calibrators eliminates the bias inherent in the direct method.

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Fatty acid composition of cholesteryl esters in serum in boys from 16 developing and developed countries

Knuiman

West

Hermus³

et al. 1980

Atherosclerosis

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Blood Serum Fatty Acid Patterns of Adolescent Boys as Influenced by Source of Dietary Fat: Corn Oil/Butter Oil, Safflower Oil/Beef Tallow

Cited by 3 publications

References 9 publications

Serum HDL/total cholesterol ratio and blood pressure in asymptomatic atherosclerotic lesions of the cervical carotid arteries in men.

Serum HDL/total cholesterol ratio and blood pressure in asymptomatic atherosclerotic lesions of the cervical carotid arteries in men.

Standardization of serum cholesterol assays by use of serum calibrators and direct addition of Liebermann-Burchard reagent.

Fatty acid composition of cholesteryl esters in serum in boys from 16 developing and developed countries

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