Blood Selenium and Glutathione Peroxidase Levels and Dietary Selenium of Free-Living and Institutionalized Elderly Subjects

Lane, Helen W.; Warren, Doris C.; Taylor, Barbara J.; Stool, Elizabeth

doi:10.3181/00379727-173-41614

Cited by 36 publications

(9 citation statements)

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“…Our results showed that gender influences GSH‐Px activity, which is higher in females in all age groups. This fact has been observed in some of the previous studies 21 , 27 , 28 but not in all 19 , 20 , 29 . It has been related to a possible higher selenium intake in females, which did not appear in our results where selenium levels did not differ with sex.…”

Section: Discussionsupporting

confidence: 48%

Selenium and Oxygen‐Metabolizing Enzymes in Elderly Community Residents: A Pilot Epidemiological Study

Berr¹,

Nicole²,

Godin³

et al. 1993

J American Geriatrics Society

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Section: Discussionsupporting

confidence: 48%

Selenium and Oxygen‐Metabolizing Enzymes in Elderly Community Residents: A Pilot Epidemiological Study

Berr¹,

Nicole²,

Godin³

et al. 1993

J American Geriatrics Society

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“…Nevertheless, Se intake did not correlate with plasma Se in either males or females in the present study. Similarly, Lane et al (1983) failed to ®nd a statistically signi®cant correlation between these variables and Snook et al (1983) only reported a weak correlation. However, Swanson et al (1990) demonstrated a highly signi®cant relationship (r 0.51) between dietary Se, measured by direct analysis, and serum Se.…”

Section: Discussionmentioning

confidence: 95%

Selenium status of a group of Scottish adults

Shortt¹,

Duthie²,

Robertson³

et al. 1997

Eur J Clin Nutr

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Objective: To examine dietary selenium intake and indices of selenium status (plasma and red blood cell selenium and glutathione peroxidase activities) in apparently healthy Scottish individuals. Design and subjects: One hundred subjects, aged between 40 and 60 y, completed a seven day weighed food intake and provided blood samples for selenium status analysis. Setting: Inverurie, Aberdeenshire, Scotland. Results: Average reported selenium intake was low (43 mg/d). A signi®cant number of subjects had reported intakes below the RNI. Low levels of plasma selenium were also found but no subject had values below 40 mg/l. Red blood cell selenium was within the reference range established for a healthy UK population. Smoking status had no consistent effect on selenium status. Conclusions:The results of the present study suggest that selenium status of certain Scottish individuals may be compromised and that further studies are warranted.

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“…Se intake is correlated with total calories and dietary protein intake [37], A strong correlation between the average daily protein and Se intake in uremic patients has been observed [21], and a correlation between whole blood Se and serum albumin and diminished TSF mea surements in dialysis patients was also reported [ 18], Con version of inorganic Se into organoselenium compounds is necessary for the biological activity of this trace metal [38]. Since these compounds depend upon amino acids, uremic patients with protein restriction and malnutrition could have reduced blood Se levels [38].…”

Section: Discussionmentioning

confidence: 99%

Geographic Factors and Plasma Selenium in Uremia and Dialysis

Bonomini

Förster

Manfrini

et al. 1996

Nephron

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The importance of selenium (Se) as an essential trace element for man has been increasingly recognized. Blood Se levels in chronic uremic patients are frequently reported to be lower than in controls. Definitive determination of the Se status in uremic patients, however, is hampered by the wide range of blood Se content in humans from different parts of the world. The present study was designed to assess and compare the Se status in two European populations from Rostock (Germany) and Chieti (Italy). Plasma Se levels were evaluated in healthy controls, chronic renal failure nondialyzed patients (CRF) and hemodialysis patients (HD). All Se determinations were performed in a single laboratory. The Se concentration was significantly higher (p < 0.005) in Italian healthy controls than in German healthy controls. In contrast, Se levels were similar in both CRF and HD patients from both cities. In both countries, the Se concentration in CRF and HD patients was significantly lower (p < 0.001) than in their corresponding controls, but no difference between CRF and HD was found. CRF and HD patients from the two countries showed quite similar laboratory and anthropometric data. In CRF patients in Chieti, a significant (p < 0.05) negative correlation between plasma Se and serum creatinine was found. In both HD groups, the length of time on HD and type of membrane dialyzer used did not influence the Se status. A significant positive correlation (p < 0.01) between Se levels and the protein catabolic rate was found in both HD groups. Uremia seems to be a strong factor which overrules the difference in Se levels that is present in healthy adults from different European countries. Uremia in itself may influence and level the Se concentration in patients with geographic diversity.

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Blood Selenium and Glutathione Peroxidase Levels and Dietary Selenium of Free-Living and Institutionalized Elderly Subjects

Cited by 36 publications

References 0 publications

Selenium and Oxygen‐Metabolizing Enzymes in Elderly Community Residents: A Pilot Epidemiological Study

Selenium and Oxygen‐Metabolizing Enzymes in Elderly Community Residents: A Pilot Epidemiological Study

Selenium status of a group of Scottish adults

Geographic Factors and Plasma Selenium in Uremia and Dialysis

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