Blood pressure and heart rate variability in menopause.

Migneco, Alessio; Montebelli, M.R.; Mettimano, Marco; Pichetti, F.; Fazzari, Loredana; Rovella, E.; Flex, Andrea; Savi, L

doi:10.1016/s0895-7061(99)80578-0

Cited by 3 publications

(4 citation statements)

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“…Proposed hypothesis, for haemodynamic changes like blood pressure variation though not clear, it maybe the expression of baroreflex impairment due to menopausal atherosclerosis. Another possibility may be the cardiovascular response to centrally induced sympathetic hyperactivity [12,13].…”

Section: Discussionmentioning

confidence: 99%

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Assessment of Blood Pressure Variability in Postmenopausal Women

Jain¹,

Kumar²,

Acharya³

et al. 2022

Cureus

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Introduction: Increase in blood pressure is the leading cause of comorbidity, especially cardiovascular and cerebrovascular disease, but its variability represents an independent risk factor for the same in menopausal women. Dramatic decrease of estrogen production in menopause interferes with many metabolic pathways leading to insulin resistance, increased body mass index (BMI) and dyslipidemia hence cardiovascular morbidity and mortality. In this study an assessment of the variability of blood pressure in postmenopausal women and its association with BMI have been highlighted.Method: In this cross-sectional study, a total of 175 postmenopausal females more than 50 years of age who were admitted to or visited medicine wards with no known major medical condition were enrolled between June and July 2019. Recording of both diastolic and systolic blood pressure of postmenopausal women was done at 6 am, 12 pm and 7 pm manually by mercury sphygmomanometer. In addition, BMI, neck circumference, and lipid profile values were also recorded.Results: Variation of both systolic and diastolic blood pressure at 6 am, 12 pm and 7 pm in association with various parameters like BMI (more than 25 kg/m 2 ) were 128.

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Section: Discussionmentioning

confidence: 99%

“…In addition, variability of BP, especially a rise during night hours, is correlated with more target organ complications. Postmenopausal females are more affected compared with males and premenopausal females in nocturnal nonreduction of BP [11][12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Assessment of Blood Pressure Variability in Postmenopausal Women

Jain¹,

Kumar²,

Acharya³

et al. 2022

Cureus

View full text Add to dashboard Cite

show abstract

“…The loss of estrogen in menopause leads to increased sympathetic nervous activity and changes in endothelial function[1] which could theoretically lead to greater variation in BP. A previous study did find increased BPV in postmenopausal women [36], but it recruited patients from a hypertension clinic. Our study in contrast excluded women with any history of cardiovascular disease or hypertension.…”

Section: Discussionmentioning

confidence: 99%

Blood pressure variability in normotensive perimenopausal women: Non-dipping status, maximum blood pressure and arterial stiffness

Wali

Raparelli

Pilote

et al. 2021

International Journal of Cardiology

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“…They proposed that menopausal status, aging and BMI increase may all, independently, contribute to the enhanced blood pressure variability found in menopausal women. 11 Zaydun G et al concluded that menopause augments the age-related increase in arterial stiffness, and this effect is related at least in part to estrogen deficiency during the early postmenopausal phase. 12 During menopausal transition, due to decrease in estrogen levels, plasma renin activity and sympathetic activity are increased and prevention of conversion of Angiotensin I to Angiotensin II will be reduced.…”

Section: Changes In Blood Pressurementioning

confidence: 99%

Comparison of Obesity Indices and Blood Pressure in Sample of Pre - Menopausal and Post - Menopausal Women

Suguna¹,

S²

2015

jemds

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ABSTRACT:Menopause is accompanied by increased risk of cardiovascular morbidity. Withdrawal of protective effect of estrogen has been documented to produce changes in lipid and glucose metabolism, body weight and fat distribution, vascular resistance and host of other mechanisms. Several parameters have been proposed as markers for increased cardiovascular risk in postmenopausal women. But what are the simplest markers that can be easily measured and monitored? Study attempts to examine changes in Blood pressure, Body weight, Body Mass Index (BMI) and Waist-hip ratio (WHR) during menopausal transition. METHOD: A comparative study involving 30 pre-menopausal and 30 post-menopausal women. Anthropological measures (Height, Weight, BMI, WHR, Waist circumference, Hip circumference) and cardiovascular parameters (Systolic and Diastolic blood pressure) were recorded and compared between the two groups. RESULTS: Post-menopausal women had greater body weight (p 0.046), BMI (p 0.05), waist circumference (p 0.005), Hip circumference (p 0.002), compared to pre-menopausal women. More number of Post-menopausal women was hypertensive compared to pre-menopausal women (p 0.024). CONCLUSION: Postmenopausal women have greater propensity for obesity and hypertension. These conditions should be monitored and targeted for intervention in order to reduce cardiovascular risk in this population. KEYWORDS: Pre-menopausal women, Post-menopausal women, Body Mass Index, Waist circumference, Waist-Hip ratio, Systolic Blood pressure, Diastolic Blood pressure, Hypertension, Obesity. MeSHTERMS: Premenopause, Postmenopause, Obesity, Hypertension, Coronary disease. INTRODUCTION:Menopause is not a disease but a physiological phase of a woman's life. However, due to the changing hormonal milieu, this phase is accompanied by several bodily changes affecting both physical and metabolic profile of the woman. These changes are known to predispose postmenopausal women to increased cardiovascular risk.Women develop coronary heart disease relatively late in life, with menopause (Natural or surgical) making a precipitous climb in Coronary Heart Disease (CHD) rates. 1 After menopause, cardiovascular disease risk increases more steeply in women than in men. The accelerated risk around the age of menopause has been explained by the loss of a protective factor estrogen or unmasking of a risk factor androgen. Decline in estrogen levels doubles and triples the risk of Cardio Vascular Diseases (CVD) through its metabolic and vascular consequences. 2 As the population ages, both the number of older women and the prevalence of CVD are expected to increase. With each decade of life, the death rate from CVD among women increases three to five fold.Early identification and aggressive modification of CHD risk factors are critical in preventing the onset of coronary disease and reducing its mortality. Intervention can be done in the form of screening, counseling and initiation of remedial measures for primary prevention of CHD.

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Blood pressure and heart rate variability in menopause.

Cited by 3 publications

References 0 publications

Assessment of Blood Pressure Variability in Postmenopausal Women

Assessment of Blood Pressure Variability in Postmenopausal Women

Blood pressure variability in normotensive perimenopausal women: Non-dipping status, maximum blood pressure and arterial stiffness

Comparison of Obesity Indices and Blood Pressure in Sample of Pre - Menopausal and Post - Menopausal Women

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