Blood pressure and heart rate variability and baroreflex sensitivity in white-coat, masked, and sustained hypertension

Sheng, Chang‐Sheng; Li, Fei-Ka; Cheng, Yi‐Bang; Wei, Fang‐Fei; Huang, Jianfeng; Guo, Qian‐Hui; Zhang, Dongyan; Wang, Ying; An, De‐Wei; Huang, Qi‐Fang; Li, Yan; Wang, Ji‐Guang

doi:10.1038/s41440-020-0413-5

Cited by 14 publications

(7 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It was therefore speculated that the enhancement of sympathetic nerve activities out of the clinic promoted the development of MUCH. Another study found that sympathetic nerve activities in patients with MH was significantly higher than those with normal blood pressure [ 20 ]. These studies showed abnormal sympathetic activities in MH patients that resulted in higher blood pressure variability as compared to patients with normal blood pressure.…”

Section: Discussionmentioning

confidence: 99%

Analysis of Systolic Blood Pressure Level and Short-Term Variability in Masked Hypertension

Hou

Liu

2022

Journal of Healthcare Engineering

View full text Add to dashboard Cite

Background. Patients with masked hypertension are at an elevated risk of cardiovascular events and all-cause death. This risk is close to that of sustained hypertension. The mean value and short-term variability of systolic blood pressure are considered to be risk factors for organ damage in hypertension. Objective. To investigate the mean value and short-term variability of systolic blood pressure in patients with masked hypertension. Methods. According to the results of in-clinic and ambulatory blood pressure measurement, participants were divided into four groups: normotension group, controlled hypertension group, masked hypertension group, and sustained hypertension group. The mean value and short-term variability of systolic blood pressure of masked hypertension group were evaluated by comparison with the other three groups. Results. A total of 250 subjects were enrolled, with an average age of 65.46 ± 8.76 years, and 166 (66.4%) were male, including 62 in the normotension group, 78 in the controlled hypertension group, 69 in the masked hypertension group, and 41 in the sustained hypertension group. Compared with the normotension group and controlled hypertension group, the mean value, blood pressure load, standard deviation, and coefficient of variation of systolic blood pressure over 24 hours and during the day and night, were all higher in the masked hypertension group ( P < 0.05 ), while the rate of the nocturnal systolic blood pressure decline was lower ( P < 0.05 ). There were no statistically significant differences in the above indexes between the masked hypertension group and sustained hypertension group ( P > 0.05 ). Conclusion. There are higher mean value of systolic blood pressure and greater short-term variability in masked hypertension patients. Identification of masked hypertension is an important challenge in the clinic.

show abstract

Section: Discussionmentioning

confidence: 99%

Analysis of Systolic Blood Pressure Level and Short-Term Variability in Masked Hypertension

Hou

Liu

2022

Journal of Healthcare Engineering

View full text Add to dashboard Cite

show abstract

“…A similar study conducted by Sheng et al in 2020 involved 645 subjects, 28 of whom were white-coat hypertensive. 27 However, Sheng et al's study showed that subjects with white-coat hypertension did not show any significant signs of a lower BRS ( p ≥ 0.12). Both studies had relatively smaller sample sizes (of white-coat hypertensives); therefore, not much at this point can be concluded about low BRS preceding hypertension from these studies.…”

Section: Hypertensionmentioning

confidence: 91%

Section: Baroreceptors and Hypertensionmentioning

confidence: 94%

Role of Vascular Receptors in the Development of Hypertension in the Elderly Population

2022

View full text Add to dashboard Cite

Hypertension is a disease common in adults, with many risk factors and potentially life-threatening outcomes. Blood pressure is controlled by receptors that inform the brain about the amount of pressure inside the arteries, and the amount of oxygen and carbon dioxide in the blood, respectively. Research has revealed that baroreflex sensitivity (BRS) decreases with increasing age and that there is a high correlation between hypertension and low BRS. However, various studies with differing results have indicated that high blood pressure is what causes BRS to decline, and vice versa. Several studies have shown very conflicting results on the correlation between chemoreflex and age; there have been indications of chemoreflex having a positive, negative, and zero correlation with age. In several experiments, the surgical removal of the chemoreceptors of hypertensive rats was followed by a decrease in blood pressure. These animal experiments, and an additional noninvasive human experiment in which the chemoreceptors were temporarily “shut off,” are reasons why more attention should be given to chemoreceptors as a route of alleviating hypertension.

show abstract

“…Результаты корреляционного и множественного регрессионного анализа подтвердили, что перечисленные показатели ВСР, отражающие снижение парасимпатического тонуса, статистически значимо связаны не только с ПС, но и с другими факторами риска ССЗ: возрастом, увеличением ДАД и абдоминальным ожирением. Эти данные согласуются с имеющимися в литературе примерами снижения ВСР: при различных видах стресса (экзаменационном, стрессе, связанном с работой, и другим ПС), эссенциальной АГ, метаболическом синдроме [18,19,20].…”

Section: Heart Rate Variability and Psychosocial Stress вариабельност...unclassified

Association of Heart Rate Variability with the Psychosocial Stress Level in Men 41-44 Years Old Living in Moscow

Drapkina¹,

Rozanov²,

Kontsevaya³

et al. 2022

Racionalʹnaâ farmakoterapiâ v kardiologii

View full text Add to dashboard Cite

Aim. Research of the association of heart rate variability (HRV) with the level of psychosocial stress (PS) and other indicators of the risk of cardiovascular diseases in a sample of 41-44-year-old men living in Moscow.Material and methods. A total of 299 men aged 41-44 years were examined. The study included a clinical examination and a survey using a standard questionnaire. The categorization of risk factors (RF) for cardiovascular diseases (CVD) was carried out in accordance with generally accepted criteria The psychosocial stress was assessed using the Reeder scale. Depending on the psychosocial stress level, all surveyed men were divided into 3 groups by terciles: group 1 (3,28-4,0 points) – mild stress, group 2 (2,71-3,14) – moderate stress, group 3 (1,28-2,57) – severe stress. The analysis of HRV was performed on the basis of a short recording of an electrocardiogram using the original software package.Results. Nonparametric ANOVA showed that the mean [M (95% CI)] values of the HRV time domain (SDNN, rMSSD and the state of regulatory reserves) were lower in the group of men with high PS compared with the group with low PS [25.3 ms (20.9-29.7) versus 40.5 ms (30.7-50.3), p=0.007; 29.5 ms (24.6-34.3) versus 49.5 ms (36.7-62.3), p=0.030; and 46.7 (44.7-48.6) versus 49.7 (48.1-51.4), p=0.019; respectively]. On the contrary, the mean values [M (95% CI)] of the integral indicators of HRV (SI and IVR) were higher in the group of men with high PS [635.8 c.u. (556.2-715.4) versus 488.9 (423.8-554.1), p=0.005; 1172.6 (1045.1-1300.1) versus 904.7 (790.0-1019.4), p=0.003; respectively]. The results of correlation and multiple regression analysis confirmed that these HRV indicators are statistically significantly associated not only with PS, but also with other indicators (age, waist / hip ratio, diastolic blood pressure). However, their predictive value turned out to be low, and the proportion of the explained variance of HRV indices ranged from 2.5 to 13.1%.Conclusion. The weakening of the autonomous regulation of the heart rate with a decrease in the activity of the parasympathetic link, the activation of the central circuit of regulation with the prevalence of sympathetic influences, a decrease in the functional reserves of the heart rate regulation system are associated with an increase in the level of PS and other indicators of the risk of cardiovascular diseases.

show abstract

Blood pressure and heart rate variability and baroreflex sensitivity in white-coat, masked, and sustained hypertension

Cited by 14 publications

References 26 publications

Analysis of Systolic Blood Pressure Level and Short-Term Variability in Masked Hypertension

Analysis of Systolic Blood Pressure Level and Short-Term Variability in Masked Hypertension

Role of Vascular Receptors in the Development of Hypertension in the Elderly Population

Association of Heart Rate Variability with the Psychosocial Stress Level in Men 41-44 Years Old Living in Moscow

Contact Info

Product

Resources

About