“…indicating that lysine was being more efficiently utilized by the tissues or that the absorption of lysine from the small intestine was altered in some manner. These data are not in complete agreement with data reported by Puchal (1962) who found that in some -instances the amino acids were higher in plasma concentration, except for glycine, lysine, histidine, and arginine which decreased when methionine was added to the basal ration. Methionine hydroxy analogue (Puchal, 1962) was used instead of methionine which may account for these discrepancies.…”
Section: Methodscontrasting
confidence: 92%
“…Essentially no difference in growth rate was observed when pigs were fed the basal ration as compared to those fed the basal ration with added methionine, valine, threonine, It would appear that lysine addition to soybean protein may be responsible for the growth depression as compared to those pigs fed the other amino acid supplemented diets, as a similar response was noted in Experiment 1143 and by Puchal (1962).…”
Section: Methodsmentioning
confidence: 70%
“…Plasma amino acid concentrations were not determined in this experiment. Puchal (1962) showed that threonine, lysine, arginine, and valine exhibited a low blood plasma concentration when the methionine supple mented soybean protein was fed to pigs as compared to those fed the unsupplemented protein. Reports by Hill et al (1961) have indicated that correcting the low blood plasma level of a deficient amino acid in a given protein results in a marked decrease in the concentration of the next limiting amino acid(s) which supposedly are handicapping protein synthesis.…”
Section: Methodsmentioning
confidence: 99%
“…Recently, Puchal (1962) reported that no appreciable differences were observed in the amino acid pattern of portal or anterior vena cava plasma in the ratios of one amino acid to another or in the quantitative presence of these amino acids in young pigs. However, only values for ornithine, lysine, histidine, arginine, and tyrosine-phenylalanine were reported.…”
Section: Portal Versus Systemic Blood Plasma Free Amino Acidsmentioning
confidence: 99%
“…Longnecker and Hause (1959) have indicated that the free plasma amino acid concentration reflects the amino acid composition of the ration, if it was postulated that the amino acids were removed from the plasma in proportion to their requirements. Puchal (1962) has presented data which indicate that the plasma amino acid levels of baby pigs reflect the amino acid composition of the ingested protein.…”
“…indicating that lysine was being more efficiently utilized by the tissues or that the absorption of lysine from the small intestine was altered in some manner. These data are not in complete agreement with data reported by Puchal (1962) who found that in some -instances the amino acids were higher in plasma concentration, except for glycine, lysine, histidine, and arginine which decreased when methionine was added to the basal ration. Methionine hydroxy analogue (Puchal, 1962) was used instead of methionine which may account for these discrepancies.…”
Section: Methodscontrasting
confidence: 92%
“…Essentially no difference in growth rate was observed when pigs were fed the basal ration as compared to those fed the basal ration with added methionine, valine, threonine, It would appear that lysine addition to soybean protein may be responsible for the growth depression as compared to those pigs fed the other amino acid supplemented diets, as a similar response was noted in Experiment 1143 and by Puchal (1962).…”
Section: Methodsmentioning
confidence: 70%
“…Plasma amino acid concentrations were not determined in this experiment. Puchal (1962) showed that threonine, lysine, arginine, and valine exhibited a low blood plasma concentration when the methionine supple mented soybean protein was fed to pigs as compared to those fed the unsupplemented protein. Reports by Hill et al (1961) have indicated that correcting the low blood plasma level of a deficient amino acid in a given protein results in a marked decrease in the concentration of the next limiting amino acid(s) which supposedly are handicapping protein synthesis.…”
Section: Methodsmentioning
confidence: 99%
“…Recently, Puchal (1962) reported that no appreciable differences were observed in the amino acid pattern of portal or anterior vena cava plasma in the ratios of one amino acid to another or in the quantitative presence of these amino acids in young pigs. However, only values for ornithine, lysine, histidine, arginine, and tyrosine-phenylalanine were reported.…”
Section: Portal Versus Systemic Blood Plasma Free Amino Acidsmentioning
confidence: 99%
“…Longnecker and Hause (1959) have indicated that the free plasma amino acid concentration reflects the amino acid composition of the ration, if it was postulated that the amino acids were removed from the plasma in proportion to their requirements. Puchal (1962) has presented data which indicate that the plasma amino acid levels of baby pigs reflect the amino acid composition of the ingested protein.…”
Signature was redacted for privacy.Signature was redacted for privacy.Signature was redacted for privacy. Table The plasma protein levels were found to be higher at six weeks of age than at four weeks of age as can be seen in Table 8. The result of increasing the dietary protein level seemed to be an increase in the plasma 47 . (1959)). This difference was not seen at two weeks, thus one assumption which can be made is that such differences do take time to develop, and in kwashiorkor studies the patients were exposed to extremely low protein intakes. The potassium supplementation of the rations caused a reduction of the plasma protein levels but it is doubtful that this is a cat ionic effect. As the reduc tion was small it may be an artifact.
TABLE OF CONTENTS
INTRODUCTIONThe alpha amino nitrogen content of the plasma is much higher after four weeks of feeding the experimental rations than after two weeks.
These results are in agreement with the work of Puchal (1962) who reportedthat the free plasma amino acids increased with increasing age. The supplementation with potassium was again found to decrease the alpha amino nitrogen levels after two weeks of feeding the experimental rations.The sodium content of the plasma was quite variable and generally rather higher than the values previously reported for the baby pig (Hannan (1959)). In this work the sodium values did not appear to be altered by the protein content of the ration or the amino acid supplementation.The free plasma basic amino acids are summarized in Table 11. The values quoted for total basic amino acids is the sum of the arginine, histidine, lysine and ornithine, all of which can act as cations at physiological pH values. In general it will be noticed that increasing the level of protein in the ration increased the amino acid values. This effect was more pronounced after two weeks of the experiment than after four 49 Tables 3, 4 and 5, and the calculated analysis in Table 6. Each ration was also supplemented with 2 per cent potassium acetate.Blood samples were again collected after 14 and 28 days of feeding the experimental rations. Plasma free amino acids, protein, sodium and potassium content were measured in these samples.
Results and discussionIn contrast to the results of Experiment 1127, it was found in this experiment that the growth ratw was increased by the addition of potassium at all protein levels. These results are shown in (7.4) (8.3) (6.9) (7.6) (7.2) (7.7) of these data are shown in Table 18 Another observation to be made from the analysis in Table 18 1 152 120 120 144 160 126 2 174 126 160 166 144 139 3 166 190 166 190 216 183 4 144 150 150 150 150 150 5 150 155 155 150 150 150 Ave. (157) (148) (150) (160) (164) (148)Increasing the dietary protein levels also increased the level of plasma proteins (Table 19) The summary of the free plasma amino acids can be found in Table 20.In general the free amino acids were increased with increasing age from four to six weeks. Potassium t...
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