Blood lipids and angina pectoris (by epidemiological cardiological Rose questionnaire) in the population of 25-45 years of Novosibirsk

Abstract

The aim of the study was to investigate the prevalence of angina pectoris (AP) according to the standardized epidemiological questionnaire of Rose in the population of 25–45 years of Novosibirsk and to identify its association with some lipid and non-lipid risk factors for coronary heart disease (CHD). Material and methods. Cross-sectional survey of the population aged 25–45 in Novosibirsk was carried out. The study included 1439 people (656 men and 783 women). Within the framework of the complex survey program, the standardized epidemiological questionnaire of Rose (WHO, 1984) was used. Blood levels of total cholesterol (total C), triglycerides (TG), low and high density lipoprotein cholesterol (LDL–C, HDL–C) were determinate by biochemical methods. Results. For all lipid indicators, significant differences were found between men and women. The levels of total C, TG and LDL–C were significantly higher, and the level of HDL–C was lower in men, than in women. According to the Rose questionnaire, out of 1439 people included in the study, 12 patients (0.8%) had AP (75% women). In persons with AP, blood levels of TG were 1.8 times higher, and the levels of HDL–C in blood was 1.2 times lower compared to persons without AP. Univariate analysis of associations of AP with CHD risk factors showed that the chance of developing angina pectoris in the population of 25–45 years was significantly increased in individuals with high blood TG levels (OR 3,515, DI 1,106–11,168, p = 0.039) and low HDL–C (OR 1,203, DI 1,054–1,372, p = 0.006). A natural, although statistically not significant (OR 3,165, p=0,055, due to the small number of groups with AP) increasing in the chance of developing AP in hypertension was detected. Conclusion. In the young population of 25–45 years in Novosibirsk, elevated blood levels of TG, reduced levels of HDL–C, and hypertension were associated with AP, according to Rosecardiological questionnaire, which underlines the importance of conducting screening surveys of the young population to improve effective prevention and treatment of diseases.

Prevalence of Angina Pectoris and Associated Factors in the Adult Population of Brazil: National Survey of Health, 2019

“…This study identified an association of grade I angina with self-declared black and mixed race/color and with living in rural areas, reinforcing the relationship of social characteristics and poorer access to health promotion and preventive measures 16 . Among the study's limitations, we highlight a strong association between "positive" responses to the questionnaire and the presence of common mental disorders 4,19,20 . Thus, the positive response could be due to somatization or increased sensitivity to pain in depressed or anxious people, and not exactly to a manifestation of coronary ischemia 4,19 .…”

Pathogenetic Mechanisms of Relationship of Metabolic and Morphofunctional Disorders of Thyroid and Adrenal Glands in Diabetes Mellitus and Obesity

“…The duration of diabetes from 6 to 10 years was recorded in 35 (12.72%) patients, from 10 to 15 years -in 153 (55.63%) patients, more than 15 years -in 87 (31.63%) patients. In the studied patients, the Rose [4], [5], questionnaire recommended by the WHO for the detection of exertional angina, anamnestic data on hospitalization with angina pectoris or myocardial in fact, data of daily monitoring of ECG, and EchoCG was used for screening. The average duration of IHD in patients was 10.7 ± 1.47 years.…”