Blood lead—Tooth lead relationship among Boston children

Rabinowitz, Michael; Leviton, Alan; Bellinger, David C.

doi:10.1007/bf01701924

Cited by 37 publications

(30 citation statements)

References 14 publications

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“…Variability of lead concentration in relation to the tooth type has been confirmed in former studies [54,55]. Even in the last decade research of lead concentration showed significant variability when comparing teeth type.…”

Section: Comparative Studies Of Lead Levels In Human Teethmentioning

confidence: 64%

Teeth as Indicators of Environmental Pollution with Lead

Kamberi¹,

Koçani²,

Dragusha³

2012

J Environment Analytic Toxicol

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Section: Comparative Studies Of Lead Levels In Human Teethmentioning

confidence: 64%

Teeth as Indicators of Environmental Pollution with Lead

Kamberi¹,

Koçani²,

Dragusha³

2012

J Environment Analytic Toxicol

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“…The pulpal canal in the cervical section was usually resorbed to varying degrees, but approximately 2 mm of the pulpal canal and dentin was reamed out, to ensure minimal contribution from secondary (circumpulpal) dentin. The dentin in the cervical section provides an integrated exposure to lead from the time of eruption of the tooth until exfoliation (Purchase and Fergusson 1986;Rabinowitz et al 1989Rabinowitz et al , 1991.…”

Section: Methodsmentioning

confidence: 99%

Identification of sources of lead in children in a primary zinc-lead smelter environment.

Gulson

Mizon

Davis

et al. 2004

Environ Health Perspect

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We compared high-precision lead isotopic ratios in deciduous teeth and environmental samples to evaluate sources of lead in 10 children from six houses in a primary zinc-lead smelter community at North Lake Macquarie, New South Wales, Australia. Teeth were sectioned to allow identification of lead exposure in utero and in early childhood. Blood lead levels in the children ranged from 10 to 42 micro g/dL and remained elevated for a number of years. For most children, only a small contribution to tooth lead can be attributed to gasoline and paint sources. In one child with a blood lead concentration of 19.7 microg/dL, paint could account for about 45% of lead in her blood. Comparison of isotopic ratios of tooth lead levels with those from vacuum cleaner dust, dust-fall accumulation, surface wipes, ceiling (attic) dust, and an estimation of the smelter emissions indicates that from approximately 55 to 100% of lead could be derived from the smelter. For a blood sample from another child, > 90% of lead could be derived from the smelter. We found varying amounts of in utero-derived lead in the teeth. Despite the contaminated environment and high blood lead concentrations in the children, the levels of lead in the teeth are surprisingly low compared with those measured in children from other lead mining and smelting communities.

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“…Teeth have been analyzed for lead using AAS and ASV (Rabinowitz et al 1989;Steenhout and Pourtois 1981). Samples must be dry ashed or digested with acid prior to analysis.…”

Section: Methodsmentioning

confidence: 99%

“…Tooth lead has been considered a potential biomarker for measuring long-term exposure to lead (e.g., years) because lead that accumulates in tooth dentin and enamel appears to be retained until the tooth is shed or extracted (Ericson 2001;Gomes et al 2004;Omar et al 2001;Rabinowitz et al 1989;Steenhout and Pourtois 1987). Formation of enamel and coronal dentin of deciduous teeth is complete prior to the time children begin to crawl; however, lead in shed deciduous teeth is not uniformly distributed.…”

Section: Bone and Tooth Lead Measurements The Development Of Noninvamentioning

confidence: 99%