Blood-Groups and Secretor Status in Patients With Salivary-Gland Tumours

Garrett, J. V.; Whittaker, J. S.; Nicholson, Andrew C.; Ridway, J C; Bowman, Clive

doi:10.1016/s0140-6736(71)90490-9

Cited by 12 publications

(4 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The analysis of the blood group distribution among the patients and controls has been shown in presence of esophageal cancer more in blood group B followed by A (0.027). For salivary gland cancer patients also, blood group A was found in majority of the patients which is contrary to the results of Garrett JV et al, in which no significant relation was found between blood group and salivary cancer [25]. However, Laryngeal cancer was found to be more in blood Group B which is contradictory to the results by Adam SI et al, who showed a higher prevalence among patients with blood Group A [26].…”

Section: Resultscontrasting

confidence: 75%

Relative Risk of Various Head and Neck Cancers Among Different Blood Groups: An Analytical Study

Singh¹

2014

JCDR

View full text Add to dashboard Cite

show abstract

Section: Resultscontrasting

confidence: 75%

Relative Risk of Various Head and Neck Cancers Among Different Blood Groups: An Analytical Study

Singh¹

2014

JCDR

View full text Add to dashboard Cite

show abstract

“…The results of Vidas and Temmer’s study (1999) showed no significant difference in saliva secretor status of patients with premalignant oral lesions (lichen planus, leukoplakia, etc.) (p = 0.05) meanwhile a higher intensity of these lesions was found in the non-secretor group (p = 0.01) that indicates the progression of pre-malignant oral lesions in this group of patients [31].…”

Section: Discussionmentioning

confidence: 99%

Salivary Secretor Status of Blood Group Antigens in Patients with Head and Neck Cancer

Bakhtiari¹,

Far²,

Alibakhshi³

et al. 2019

Open Access Maced J Med Sci

View full text Add to dashboard Cite

BACKGROUND: Head and neck cancers include malignancies of the scalp and neck skin, nasal cavity, paranasal sinuses, oral cavity, salivary glands, pharynx and larynx. The term ABO secretor refers to people who secrete blood group antigens in their body fluids such as saliva, sweat, tears, semen, and serum. Non-secretors refer to those who do not secrete their blood group antigens in their body fluids. The lack of blood type antigens in body discharge increases the susceptibility to certain types of diseases and infection. AIM: Our study aimed to investigate the relationship between the secretion of blood groups in the saliva of patients with head and neck cancers. MATERIAL AND METHODS: This case-control study was performed on 110 people (57 patients with head and neck cancer who were referred to Imam Khomeini Hospital, Tehran and 53 cancer-free controls). Five ml of non-stimulated saliva were collected by the spitting method. By agglutination or lack of agglutination in the test tubes, we determined the patient’s secretor or non-secretor condition. RESULTS: In terms of secretor status, 52.7% of all samples were secretors. In the case group, 19 out of 57 cases (33.3%) were secretors, and 38 were non-secretors (66.7%). In the control group, 39 out of 53 cases (73.6%) were secretors, and 14 cases were non-secretors (26.4%). There was a significant difference in the percentage of non-secretors between the two groups (p = 0.00). CONCLUSION: People with non-secretor status may be more prone to develop head and neck cancer. The presence of these antigens in saliva may have a protective effect.

show abstract

“…1). Patients with blood 19 and Garret et al 16 reported no relationship between SGT and ABO blood group; Pinkston has rather reported a lower percentage of blood group A in cases than control group. 19 Osborne et al showed this relationship and also reported a high incidence of SGT in blood group A.…”

Section: Abo Blood Group and Risk Of Salivary Gland Tumoursmentioning

confidence: 95%

“…There were conflicting reports about the relationship between the ABO blood groups and these tumors. 16,17 Therefore, we decided to conduct this study to evaluate the relationship between SGT and ABO blood group.…”

mentioning

confidence: 99%

Determining the Association of Benign and Malignant Salivary Gland Tumours with ABO-Rh Blood Groups

Oroei

2019

BJOHNS

View full text Add to dashboard Cite

Introduction Various studies have proposed that some ABO blood groups may be associated with increased risk of cancer. Hence, we decided to conduct this study to investigate the relationship between ABO-Rh blood group and risk of salivary gland tumor. Materials and Methods In this study, 190 patients with salivary gland tumor and 400 healthy persons were investigated. Demographical information including ABO blood group of both groups were collected and analyzed using the SPSS 18 version. Binary logistic regression (univariate and multivariate model) were applied with 95% confidence interval. Results The most common blood group in patients with salivary gland tumor was blood group O. There was no significant relationship between the ABO blood group and salivary gland tumor risk (All; p>0.05). The blood group O and A were the most abundant blood groups in patients with the malignant and benign salivary gland tumor respectively (46.6%, 35.7%).The risk of malignancy of tumor in the patients with blood group O was marginal (1.84; 95%CI: 0.96-3.53, p: 0.06). Conclusion This study shows no relationship between ABO-Rh blood groups and salivary gland tumor risk. However, to reach a definitive conclusion about the risk of malignancy in blood group O, stronger studies are needed in the future.

show abstract

Blood-Groups and Secretor Status in Patients With Salivary-Gland Tumours

Cited by 12 publications

References 6 publications

Relative Risk of Various Head and Neck Cancers Among Different Blood Groups: An Analytical Study

Relative Risk of Various Head and Neck Cancers Among Different Blood Groups: An Analytical Study

Salivary Secretor Status of Blood Group Antigens in Patients with Head and Neck Cancer

Determining the Association of Benign and Malignant Salivary Gland Tumours with ABO-Rh Blood Groups

Contact Info

Product

Resources

About