Blood group terminology 2004: from the International Society of Blood Transfusion committee on terminology for red cell surface antigens

Daniels, Geoff; Fletcher, Anne; Garratty, George; Henry, Stephen; Jørgensen, Jan Stener; Judd, W. John; Levene, C.; Lomas‐Francis, Christine; Moulds, John J.; Moulds, Joann M.; Moulds, Marilyn; Overbeeke, M. A. M.; Reid, Marion E.; Rouger, Ph.; Scott, Marion L.; Sistonen, Pertti; Smart, Elizabeth; Tani, Yoshihiko; Wendel, Silvano; Zelinski, Teresa

doi:10.1111/j.1423-0410.2004.00564.x

Cited by 148 publications

(104 citation statements)

References 63 publications

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“…the antigens K and k), rhesus (C, c, C w , E and e), Duffy (Fy a and Fy b ), Kidd (Jk a and Jk b ), etc. 7 The population prevalence of these blood group antigens shows wide variation: for example, 9% for the K antigen, 99% for the k antigen, 82% for the c antigen, 65% for the C antigen and only 2% for the C w antigen in Caucasians. 8 As a consequence, the probability that a woman who lacks a specific blood group antigen will be exposed to this antigen varies considerably.…”

Section: Introductionmentioning

confidence: 99%

Risk factors for the presence of non‐rhesus D red blood cell antibodies in pregnancy*

Koelewijn

Vrijkotte

Haas

et al. 2009

BJOG

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Objective To identify risk factors for the presence of non-rhesus D (RhD) red blood cell (RBC) antibodies in pregnancy. To generate evidence for subgroup RBC antibody screening and for primary prevention by extended matching of transfusions in women <45 years.Design Case-control study.Setting Nationwide evaluation of screening programme for non-RhD RBC antibodies. Methods Data collection from the medical records and/or from the respondents by a structured phone interview.Main outcome measures Significant risk factors for non-RhD immunisation in multivariate analysis.Results Significant independent risk factors: history of RBC transfusion (OR 16.7;), parity (para-1 versus para-0: OR 1.3; 95% CI: 1.0-1.7; para-2 versus para-0: OR 1.4; 95% CI: 1.0-2.0; para >2 versus para-0: OR 3.2; 95% CI: 1.8-5.8), haematological disease (OR 2.1; 95% CI: 1.0-4.2), history of major surgery (OR 1.4; 95% CI: 1.1-1.8). For the clinically most important antibodies, anti-K, anti-c and other Rh-nonDantibodies RBC transfusion was the most important risk factor, especially for anti-K (OR 96.4; 95%-CI: 56.6-164.1); 83% of the K-sensitised women had a history of RBC transfusion. Pregnancyrelated risk factors were a prior male child (OR 1.7; 95% CI: 1.2-2.3) and caesarean section (OR 1.7; 95% CI: 1.1-2.7).Conclusions RBC transfusion is by far the most important independent risk factor for non-RhD immunisation in pregnancy, followed by parity, major surgery and haematological disease. Pregnancy-related risk factors are a prior male child and caesarean section. Subgroup screening for RBC antibodies, with exclusion of RhD-positive para-0 without clinical risk factors, is to be considered. This approach will be equally sensitive in detecting severe Haemolytic Disease of the Fetus and Newborn compared with the present RBC antibody screening programme without preselection. Primary prevention by extending preventive matching of transfusions in women younger than 45 will prevent more than 50% of pregnancy immunisations.

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Section: Introductionmentioning

confidence: 99%

Risk factors for the presence of non‐rhesus D red blood cell antibodies in pregnancy*

Koelewijn

Vrijkotte

Haas

et al. 2009

BJOG

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“…The most common non-acid glycosphingolipid on erythrocytes is globoside (globotetraosylceramide (Gb4) 4 ), also known as the P antigen (9). It is currently the only antigen in the GLOB blood group system (ISBT 028) (10). The P antigen is the product of UDP-N-acetylgalactosamine: globotriaosylceramide 3-␤-N-acetylgalactosaminyltransferase (P synthase; ␤1, 3GalNAc-T1; EC 2.4.1.79) encoded by the gene B3GALNT1 on chromosome 3q26.1 (11)(12)(13).…”

mentioning

confidence: 99%

Identification of the Molecular and Genetic Basis of PX2, a Glycosphingolipid Blood Group Antigen Lacking on Globoside-deficient Erythrocytes

Westman

Benktander

Storry

et al. 2015

Journal of Biological Chemistry

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Background: Expression of x 2 glycosphingolipid (PX2) is elevated on erythrocytes from individuals with the rare P/P1/P knegative p phenotype. Results: Globoside-deficient individuals with mutated P synthase (␤1,3GalNAc-T1) lack PX2 and have anti-PX2 in plasma. Transfection of B3GALNT1 induces P and PX2 expression. Conclusion: PX2 synthesized by ␤1,3GalNAc-T1 fulfills blood group criteria. Significance: ␤1,3GalNAc-T1 uses different acceptors to form immunologically distinct glycosphingolipids.

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“…La determinación de índices de mezcla utilizando los grupos sanguíneos clásicos ha sido ampliamente empleada en epidemiología 3 . Como es sabido, el sistema ABO, descubierto por Karl Landsteiner en 1900, está compuesto por los antígenos A y B, y los correspondientes anticuerpos contra estos antígenos 4 . El gen ABO, ubicado en el cromosoma 9, posee tres alelos A, B y O, que varían de acuerdo a las sustituciones de nucleóti-dos, las cuales determinan las especificidades de las enzimas para las cuales codifican.…”

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Estimadores de mezcla amerindia basados en métodos serológicos y moleculares

Pulgar-Alarcón¹,

Fuentes-Guajardo

Llop

et al. 2015

Rev. méd. Chile

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Blood group terminology 2004: from the International Society of Blood Transfusion committee on terminology for red cell surface antigens

Cited by 148 publications

References 63 publications

Risk factors for the presence of non‐rhesus D red blood cell antibodies in pregnancy*

Risk factors for the presence of non‐rhesus D red blood cell antibodies in pregnancy*

Identification of the Molecular and Genetic Basis of PX2, a Glycosphingolipid Blood Group Antigen Lacking on Globoside-deficient Erythrocytes

Estimadores de mezcla amerindia basados en métodos serológicos y moleculares

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