Blood gases and acid-base balance in children with bronchial asthma

Oberger, E; Engström, Ingemar

doi:10.1007/bf02730685

Cited by 12 publications

(3 citation statements)

References 27 publications

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“…l8 The same mechanism is responsible for observed correlations between blood gases and lung function in acute exacerbations of a~thma'~3~' and be- tween measures of impaired gas exchange and clinical scoring systems in acute asthma. 21,22 It follows, that ventilation-perfusion mismatching is the most likely mechanism responsible for the observed, provocationinduced fall of PtcO, in the present study.…”

Section: Discussionsupporting

confidence: 62%

Cold air challenge of airway reactivity in children: A correlation of transcutaneously measured oxygen tension and conventional lung functions

Eber

Varga

Zach

1991

Pediatric Pulmonology

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For pharmacological challenges, a correlation between the induced changes of the transcutaneously measured oxygen tension (PtcO2) and of conventional pulmonary function tests (PFTs) has been documented. We performed a 4-minute cold air challenge (CACh) in 17 children with bronchial asthma under continuous monitoring of PtcO2, and correlated observed changes with CACh-induced alterations of conventional PFTs. PtcO2 decreased significantly with CACh (from 86 +/- 10 mmHg to 66 +/- 14 mmHg, P less than 0.001), but returned to near-baseline within the next 30 minutes. PFTs changed with a similar pattern; the closest correlation was found between the CACh-induced fall of PtcO2 and Delta-FEV1 (r = 0.833, P less than 0.001). Changes of FVC, PEF, and Vmax50 correlated significantly as well. PtcO2 can complement or substitute for conventional PFTs in assessing the response to CACh in children.

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Section: Discussionsupporting

confidence: 62%

Cold air challenge of airway reactivity in children: A correlation of transcutaneously measured oxygen tension and conventional lung functions

Eber

Varga

Zach

1991

Pediatric Pulmonology

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“…AS Asthma score; [13] ASS asthma severity score; [14][15][16][17][18][19] BS bronchiolitis score (original names: BS-2 respiratory scale; BS-3 clinical scoring; BS-4 severity score); [20][21][22][23] CAES clinical asthma evaluation score (original names: CAES-2 clinical severity score or modified clinical asthma score; CAES-3 modified clinical asthma score); [24][25][26][27] CAS clinical asthma score [28]; CS clinical score [29]; CSGS clinical symptom grading system; [30,31] CSS clinical scoring system (original names: CSS-2 modified Tal's clinical score; CSS-4 clinical score); [6,[32][33][34][35][36][37][38][39][40][41] EDRAR escala de diffcultad respiratoria de la Argentina; [42] EDRCH escala de dificultad respiratoria de Chile;41 MPIS modified pulmonary index score; [43] PASS pediatric asthma severity score; [44,45] PRAM paediatric or preschool respiratory assessment measure; [45][46][47] PIS pulmonary index score; [48][49][50][51][52][53]…”

Section: Abbreviations Of the Scores With Referencesmentioning

confidence: 99%

Systematic review: Insufficient validation of clinical scores for the assessment of acute dyspnoea in wheezing children

Bekhof

Reimink

Brand

2014

Paediatric Respiratory Reviews

115

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“…In such situations, methods that allow for an assessment of the severity of the obstruction are valuable. Grading systems based on clinical symptoms have been developed for this purpose and found to correlate well with the degree of obstruction (2) and the fall in arterial Po, (3).…”

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confidence: 99%

Transcutaneous Oxygen and Carbon Dioxide Levels and a Clinical Symptom Scale for Monitoring the Acute Asthmatic State in Infants and Young Children

Wennergren¹,

Engström²,

Bjure

1986

Acta Paediatrica

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Measurement of transcutaneous PO2 and PCO2 in addition to a clinical symptom grading system was used to monitor the acute asthmatic attack in children under two years of age. tcPO2 was lowered already at signs of mild obstruction and decreased in parallel with clinical deterioration. tcPCO2 was almost unchanged at mild to moderate obstructive symptoms. With clinical deterioration tcPCO2 rose steadily. An increase of the oxygen concentration to 30-40% in the inspired air increased tcPO2, on the average by 70%, but did not change the tcPCO2, level. Continuous recording of tcPO2 and tcPCO2 as well as the clinical grading system are valuable tools when monitoring severely obstructive infants and young children.

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Blood gases and acid-base balance in children with bronchial asthma

Cited by 12 publications

References 27 publications

Cold air challenge of airway reactivity in children: A correlation of transcutaneously measured oxygen tension and conventional lung functions

Cold air challenge of airway reactivity in children: A correlation of transcutaneously measured oxygen tension and conventional lung functions

Systematic review: Insufficient validation of clinical scores for the assessment of acute dyspnoea in wheezing children

Transcutaneous Oxygen and Carbon Dioxide Levels and a Clinical Symptom Scale for Monitoring the Acute Asthmatic State in Infants and Young Children

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