Blood Flow Improvement Effect of Bokbunja (Rubus coreanus) Seed Oil in High-Fat Diet-Fed Mouse Model

전혜린,; 곽성민,; 오수진,; 남현수,; 한두원,; 송윤석,; 송진우,; 최경철,

doi:10.3746/jkfn.2015.44.8.1105

Cited by 1 publication

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“…복 분자는 5~6월에 꽃이 피고 7~8월에 열매가 성숙되는데 이 과 정에서 열매가 붉게 익다가 완숙되면 흑색 빛을 띤다. 이 때 미성숙된 열매를 건조한 것을 복분자라고 하며 (Jeon et al 2015;Kim and Shin 2011;, 동의보감에 따르면 한방에서 청량, 보제(補劑), 지갈(止渴), 강장약 등의 약재로 쓰인다. 복분자는 페놀성분, 안토시아닌, 탄닌, 트리터펜 배 당체 등의 생리활성 물질을 함유하고 있으며 (Choi et al 2012), 성숙 단계별 (Cha et al 2007), 추출 방법에 따라 생리활 성 성분의 함량 변화가 발생한다 (Cho et al 2005).…”

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Antioxidant and anti-inflammatory effects of seed ethanol extracts of Rubus coreanus miquel

2022

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This study investigated the antioxidant and anti-inflammatory effects of seed ethanol extracts from Rubus coreanus Miquel (SERC). To investigate the antioxidant activity, total polyphenol and flavonoid content, ABTS and DPPH radical scavenging activity, and reducing power were measured. The total polyphenol and flavonoid contents in seed ethanol extracts of R. coreanus Miq. were 4.09 μg gallic acid equivalents (GAE)/mg and 16.25 μg quercetin equivalents (QE)/mg, respectively. DPPH and ABTS radical scavenging activity showed concentration-dependent scavenging activity, and the RC 50 values of SERC were 26.68 μg/mL and 39.30 μg/mL, respectively. Moreover, the ferric reducing antioxidant power (FRAP) assay was performed to assess the reducing power, and SERC showed 0.61 ± 0.01 mM FeSO 4 E/mg. To measure the anti-inflammatory effect, the cytotoxicity and nitric oxide (NO) production inhibitory efficacy in RAW 264.7 cells was confirmed. SERC showed a NO production inhibitory effect at 500 μg/mL without cytotoxicity. As a result of verifying the antioxidant and anti-inflammatory activity using SERC, its potential as an antioxidant and anti-inflammatory material was confirmed.

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