Blood donor complications after whole-blood donation

Newman, Bruce

doi:10.1097/01.moh.0000142105.21058.96

Cited by 60 publications

(80 citation statements)

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“…This rate is lower than the adverse effects reported at various times by Newman and others (2003,2004). 1,2 The overall rate of adverse donation reactions in our work is similar to 1.2% documented by Crocco et al (2007) among volunteer blood givers in Italy but higher than 0.6% reported by Pathak et al, among Indian blood donors. 5,6 The difference in the rate of adverse reactions to blood donation between our donors and previous rates documented by other researchers in other climes might be due to the non established reporting system for blood donation reaction in our setting.…”

Section: Discussionsupporting

confidence: 68%

“…1 In another study, he reported the occurrence of adverse effects of blood donation in a third of American donors annually with bruises 23%, sore arm 10%, fatigue 80% and vaso vagal symptoms 7%. 2 In yet another research he found bruises in 23%, sore arms in 10%, vaso vagal reactions in 7%, fatigue in 8%, nerve irritation in 0.9%, syncope in 0.1-0.3%, arterial puncture in 0.01% with 0.033% of such reaction compelling donors to seek medical care. 3 Newman et al also reported the frequency of adverse effects of blood donation to include bruise in 22.7%, sore arm in 10%, fatigue in 7.8%, and other donation reactions in 7.0% of 1000 interviewed American blood donors.…”

Section: Introductionmentioning

confidence: 99%

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Adverse Effects of Whole Blood Donation among Voluntary Blood Donors in Jos, Nigeria

Dapus¹

2015

CMR

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Abstract:Introduction: Despite collection of blood from apparently healthy individuals for allogeneic transfusion, blood givers are often faced with untoward reactions during or after blood donation. Aim: This study was to determine the rate of adverse reactions among voluntary blood donors at the National Blood Transfusion Service in Jos. Methods: All blood donors recruited by the centre between October 2012 and September 2014 were counseled and consent to participate in the research was obtained prior to donation. The age, sex, weight and blood pressure and the venue of donation were documented. The type of donation reaction during and or after donation were timed and documented. The haemoglobin level and haemoglobin phenotypes were determined. Results: Eleven thousand six hundred and fifty-five (63%) male and 37% females were studied. The overall rate of adverse effects was 2.05% with significantly higher rate of occurrence among donors aged 18-25 years (p˂0.0001), female donors (p=0.0001), weight 40-49 Kg (p=0.001), blood group B (p=0.002) haemoglobin phenotype AA (P=0.001). The rate of adverse reactions was also higher among first-time donors (p=0.002), indoor donations (p=0.001). All adverse effects documented in our donors occurred during donation (4%) and within 21 (96%) after donation. Dizziness affected 90% while severe reaction (faint) occurred in 3% of adverse reactors. Ingested meal was the vomits of all donors who vomited. Conclusion: Though adverse effects to blood donation is low in our centre, there is need for preparedness, donor education, prediction and mitigation of occurrences.

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Section: Discussionsupporting

confidence: 68%

Section: Introductionmentioning

confidence: 99%

Adverse Effects of Whole Blood Donation among Voluntary Blood Donors in Jos, Nigeria

Dapus¹

2015

CMR

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“…Yorgunlukla birlikte olmaksızın kol ağrısının bir yıllık izlem içinde %1-2 oranında kan vericilerinin geri dö-nüşü üzerine olumsuz etkisi olduğu saptanmıştır. 2 …”

Section: Kan Bağişi Nedeni̇yle Geli̇şen Kompli̇kasyonlarin Sikliği Ve öNemi̇unclassified

“…İlk kan bağışında olumsuz etkiler azaldığı ölçüde kan vericilerinin sonraki kan bağışı için gelme olasılığı artmaktadır. [1][2][3] Kan bağışı, bazı vericilerde istenmeyen komplikasyonlarla sonuçlanabilir. Hemşi-reler kan bağışına bağlı gelişebilecek komplikasyonların farkında olmalı ve yüksek risk grubundaki bireyler için gerekli önlemleri almalıdır.…”

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Complications Developed Due to Blood Donation: Review

İnce¹,

Khorshıd²

2016

Turkiye Klinikleri J Nurs

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53Kan Bağışı Nedeniyle Gelişen Komplikasyonlar Ö ÖZ ZE ET T Hastalar için kan ve kan ürünlerine olan talebin artması, tüm dünyada mücadele etmeyi gerektiren bir duruma yol açmıştır. Kan ihtiyacının karşılanması, sağlık gönüllülerine ve onların sü-rekli olarak kan ve kan ürünlerini verme istekliliğine bağlıdır. Kan bağışı genel olarak güvenli bir yöntem olarak kabul edilir. Ancak, işlem sırası ya da sonrasında şiddeti farklılık gösteren bazı istenmeyen komplikasyonlar görülebilir. Kan bağışı ile ilgili yan etkilerin sıklığı, güvenli ve uygun donörlerin olduğu havuzu azaltmaktadır. Bu da tekrarlı kan bağış oranını düşürmekte ve her geçen gün aralıksız ve sürekli artan kan ihtiyacına ilişkin talebi karşılamakta güçlüğe neden olmaktadır. Kan bağışında bulunanların genç olması, kadın olması, ilk kez kan vermesi, tahmin edilenden daha düşük kan volümüne sahip olması gibi bazı özelliklerinin, daha yüksek komplikasyon sıklığı ile iliş-kili olduğu ortaya konmuştur. Kan bağışı ile ilgili bazı reaksiyonlar ciddi sonuçlara yol açabilirler. Bunlar ekimoz, hematom, arter delinmesi, kol ağrısı, tromboflebit, enfeksiyon riski, sinir yaralanması, kronik bölgesel ağrı sendromu ve vazovagal reaksiyonlardır. Bu komplikasyonlar ve baş dön-mesi, bulantı, baygınlık gibi ilişkili semptomlar, istemli kan vericilerini, gelecekte tekrar kan bağışında bulunmaları için caydırabilir. Hemşireler kan bağışı sırasında gelişebilecek komplikasyonların farkında olmalı ve yüksek risk grubundaki bireyler için gerekli önlemleri almalıdır. Bu makalede, kan bağışı sırasında oluşan komplikasyonların önlenmesine yardım edebilecek uygulamalar sunulmuştur.A An na ah ht ta ar r K Ke el li im me el le er r: : Kan vericiler; komplikasyonlar; hemşirelik A AB BS ST TR RA AC CT T Incrementing request of blood and blood products for patients has caused a status for defiance for the blood banks in all world. Meeting the need for blood products depends on the existence of healthy volunteers and their continued availability to donate blood and blood products. While blood donation is generally accepted as a safe procedure, some adverse complications of variable severity may be observed during or after the operation. Frequent side effects associated with blood donation reduce the pool of safe and reliable donors, sinking the repeat donation rate. This in turn, reduce the blood donation rate, cause to difficulties in meeting the continually increasing demand for blood. Certain characteristics such as the young age and the female sex of the donors, first time donors and smaller estimated blood volume have been shown to be related to the frequency of complication. Some reactions related to blood donation have the potential to lead to serious results. These are, bruise, haematoma, arterial punctures, sore arm, thrombophlebitis, risk of infection, nerve injuries, chronic regional pain syndrome and vasovagal reactions. These complications and related symptoms such as dizziness, nauses and fainting can dissuade volunteer blood donors from returning to donate in the future. N...

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“…In humans, the Council of Europe recommends up to four blood donations per year in men and up to three in women, with a maximum volume of 13% TBV (Council 2011), while the United Kingdom Blood Transfusion Services recommend a maximum of three annual donations for both genders (UK 2005). Differences between both species could be related to a donation-related vasovagal reaction (VVR), a very important adverse effect in humans with reported prevalences ranging from 0.87 to 7% (Newman 2004, Newman et al 2003, Zervou et al 2005. The vasovagal reaction, a complex and still poorly understood mechanism, results in cardio inhibitory and vasodepressive effects (TrouernTrend et al 1999) that can be associated with the hypovolemic state induced by volume depletion; the orthostatic hypotensive effect, as well as the associated psychological stress caused by fear of needles, pain and the sight of blood (Wieling et al 2011).…”

Section: Introductionmentioning

confidence: 99%

Volume-dependent hemodynamic effects of blood collection in canine donors - evaluation of 13% and 15% of total blood volume depletion

Ferreira

Gopegui

Matos³

2015

An. Acad. Bras. Ciênc.

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Background: There is no consensus regarding the blood volume that could be safely donated by dogs, ranging from 11 to 25% of its total blood volume (TBV). No previous studies evaluated sedated donors. Aim: To evaluate the hemodynamic effects of blood collection from sedated and non-sedated dogs and to understand if such effects were volume-dependent. Materials and Methods: Fifty three donations of 13% of TBV and 20 donations of 15% TBV were performed in dogs sedated with diazepam and ketamine. Additionally, a total of 30 collections of 13% TBV and 20 collections of 15% TBV were performed in nonsedated dogs. Non-invasive arterial blood pressures and pulse rates were registered before and 15 min after donation. Results: Post-donation pulse rates increased significantly in both sedated groups, with higher differences in the 15% TBV collections. Systolic arterial pressures decreased significantly in these groups, while diastolic pressures increased significantly in 13% TBV donations. Non-sedated groups revealed a slight, but significant, SBP decrease. No clinical signs related to donations were registered. Conclusion: These results suggest that the collection of 15% TBV in sedated donors induces hemodynamic variations that may compromise the harmlessness of the procedure, while it seems to be a safe procedure in non-sedated dogs.

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Blood donor complications after whole-blood donation

Abstract: The incidence of complications and types of complications is more precisely defined today. Medical outcomes are better defined for vasovagal reactions, nerve injuries (irritations), and arterial puncture. These data should help physicians who encounter these entities.

Cited by 60 publications

References 34 publications

Adverse Effects of Whole Blood Donation among Voluntary Blood Donors in Jos, Nigeria

Adverse Effects of Whole Blood Donation among Voluntary Blood Donors in Jos, Nigeria

Complications Developed Due to Blood Donation: Review

Volume-dependent hemodynamic effects of blood collection in canine donors - evaluation of 13% and 15% of total blood volume depletion

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