Blood concentration of copper, cadmium, zinc and lead in horses and its relation to hematological and biochemical parameters

Massányi, Peter; Stawarz, Robert; Halo, Marko; Formicki, Grzegorz; Lukáč, Norbert; Schwarcz, Pavol; Kováčik, Anton; Tušimová, Eva; Kováčik, Jaroslav

doi:10.1080/10934529.2014.894322

Cited by 33 publications

(19 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There are several ways of the entrance to the animal organism (e.g., consumption, inhalation, through the skin) that can cause severe intoxications [ 82 ]. Therefore, thorough, and periodic monitoring of health conditions is required in polluted areas [ 9 , 16 , 83 ]. The detrimental effects of heavy metals have been reported by numerous studies.…”

Section: Environmental Pollutionmentioning

confidence: 99%

Exogenous Factors Affecting the Functional Integrity of Male Reproduction

Tirpák

Greifová

Lukáč

et al. 2021

Life

Self Cite

View full text Add to dashboard Cite

Natural processes along with increased industrial production and the irresponsible behavior of mankind have resulted in environmental pollution. Environmental pollutants can be categorized based on their characteristics and appearance into the following groups: physical, biological, and chemical. Every single one of them represents a serious threat to the male reproductive tract despite the different modes of action. Male gonads and gametes are especially vulnerable to the effect of exogenous factors; therefore, they are considered a reliable indicator of environmental pollution. The impact of xenobiotics or radiation leads to an irreversible impairment of fertility displayed by histological changes, modulated androgen production, or compromised spermatozoa (or germ cells) quality. The present article reviews the exogenous threats, male reproductive system, the mode of action, and overall impact on the reproductive health of humans and animals.

show abstract

Section: Environmental Pollutionmentioning

confidence: 99%

Exogenous Factors Affecting the Functional Integrity of Male Reproduction

Tirpák

Greifová

Lukáč

et al. 2021

Life

Self Cite

View full text Add to dashboard Cite

show abstract

“…This relationship was generally known and was described in many species (Binkowski et al , 2016 ; Binkowski and Sawicka-Kapusta, 2015a ; Nordberg et al , 2007 ). In fact, the liver and kidneys are especially prone to xenobiotic induced injury due to their central role in xenobiotic metabolism (Massanyi et al , 2014 ).…”

Section: Discussionmentioning

confidence: 99%

Presence of cadmium residues in muscle, liver and kidney of Bubalus bubalis and histological evidence

et al. 2018

View full text Add to dashboard Cite

Cadmium (Cd) concentrations were evaluated in the samples of kidney, liver and muscle of sixty-six buffaloes regularly slaughtered. Forty were raised in Campania, in the territory between the province of Naples and Caserta and twenty-six were bred in Apulia, in the province of Bari. Two aliquots were prepared for the renal and hepatic samples: one intended for the chemical analysis and the other one intended for histological investigations. Muscle samples were the subject of purely chemical investigation. In the group of forty animals raised in the Campania region, the limits imposed by EC Reg. 1881/2006 and EC Reg. 488/2014 were exceeded in three renal samples, which showed values of 1.53, 1.22 and 1.1 mg/kg respectively; in three hepatic samples, which presented values of 0.72, 0.64 and 0.61 mg/kg, and in five muscle samples, with values of 0.16, 0.16, 0.09, 0.08 and 0.07, respectively. On the other hand, in the group of animals raised and slaughtered in the province of Bari, none of the twenty-six samples examined exceeded the limits imposed by the European regulations. The histological analysis showed typical, but not pathognomonic lesions in the renal samples from the animals raised in the provinces of Naples and Caserta. The levels of Cd contamination found in the samples examined suggest that it would be correct to exclude from the human consumption, as it happens for the equines, the kidney and the liver, especially from the animals raised in some geographical areas with a high rate of pollution.

show abstract

“…Hematologic parameters were measured using Abacus Vet5 (Diatron MI Ltd., Budapest, Hungary) – a fully automatic haematological analyser which operational principle is based on differences of resistances of individual blood elements spurred thru soft microcapillaries. Following haematological parameters were analyzed: total count of leukocytes (WBC, 10 9 /l); total count of lymphocytes (LYM, 10 9 /l); percentage of lymphocytes (LYM, %); total count of monocytes (MON, 10 9 /l); percentage of monocytes (MON, %); total count of neutrophils (NEU, 10 9 /l), percentage of neutrophils (NEU, %); total count of erythrocytes (RBC, 10 12 /l); haemoglobin (HGB, g/l); haematocrit (HCT, %); average volume of erythrocytes (MCV, fl); mean corpuscular haemoglobin (MCH, pg); mean corpuscular haemoglobin concentration (MCHC, g/l); red cell distribution width (RDWc, %); total count of platelets (PLT, 10 9 /l)); percentage of platelets (PCT, %); mean platelet volume (MPV, fl) and platelet distribution width (PDWc, %) ( Massányi et al, 2014 ).…”

Section: Methodsmentioning

confidence: 99%

The effect of different sample collection methods on rabbit blood parameters

Massányi

Kohút

Argente

et al. 2020

Saudi Journal of Biological Sciences

Self Cite

View full text Add to dashboard Cite

Nowadays great deal of research is physiological field is conducted on experimental animals and there is a lot of criticism from the wide public on methods used. Therefore, recently there is a lot of effort focused on the welfare of the animals. Main aim of this study is to determine the effect of experimental sample collection method on the selected parameters of stress. In the experiment two sample collections of rabbit blood from marginal ear vein were realized – first using standard method with one person fixing the animal and other collecting the blood using gently fixating the animal. In the second groups experimental method of inserting the experimental animal into a sack and further collection in dark was realized. During the experiment the levels of cortisol – main stress indicator in organism and other health parameters of animals including mineral profile and haematological parameters were observed. Our results show no significant changes in levels of cortisol but also a decreasing tendency in the sample from the second (dark) collection. Haematological parameters were generally in the reference values and any significant changes except levels of lymphocytes and percent of lymphocytes which shown significant increase in the second collection period were found. Also the levels of mean corpuscular haemoglobin and percent of neutrophils unveiled a significant decrease in values. Values of mineral profile parameters have indicated no significant changes except the levels of phosphorus. Based on the result we can state that the experimental sample collection has no effect on blood parameters of the animals but we spectated a statistically insignificant decrease in the levels of cortisol which can suggest that the dark collection is possibly less stressful to the animals.

show abstract

Blood concentration of copper, cadmium, zinc and lead in horses and its relation to hematological and biochemical parameters

Cited by 33 publications

References 47 publications

Exogenous Factors Affecting the Functional Integrity of Male Reproduction

Exogenous Factors Affecting the Functional Integrity of Male Reproduction

Presence of cadmium residues in muscle, liver and kidney of Bubalus bubalis and histological evidence

The effect of different sample collection methods on rabbit blood parameters

Contact Info

Product

Resources

About