Abstract:Blood coagulation studies were carried out in 38 Indian soldiers who were resident at altitudes between 3690 and 5540 m for 2 years. Compared with 16 sea-level controls, 6 of these 38 subjects who had developed pulmonary hypertension during their stay at high altitude showed a significant increase of plasma fibrinogen, fibrinolytic activity, platelet adhesiveness, platelet factor 3, factor V, and factor VIII. In the remaining 32 subjects who did not develop pulmonary hypertension there was a significant increa… Show more
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