Blood banking in China

Shan, Hua; Wang, Jing Xing; Ren, Fu Rong; Zhang, Yuan Zhi; Hai, Zhao; Gao, Guo Jing; Ji, Yang; Ness, Paul M.

doi:10.1016/s0140-6736(02)11669-2

Cited by 137 publications

(170 citation statements)

References 5 publications

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“…Similar scenarios were also reported in many other provinces (36). To eliminate this risk, the central government in China has outlawed the use of paid blood donations since 1998 (37). This change was reflected in the five BSPs, each with an abrupt slowing in the HCV-infected population growth starting in 1999 to 2000.…”

Section: Discussionmentioning

confidence: 56%

The Current Hepatitis C Virus Prevalence in China May Have Resulted Mainly from an Officially Encouraged Plasma Campaign in the 1990s: a Coalescence Inference with Genetic Sequences

Lü

Tong

et al. 2013

J Virol

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In this study, we investigated hepatitis C virus (HCV) molecular epidemiology and evolutionary dynamics. Both E1 and NS5B sequences were characterized in 379 of 433 patients in southern China and classified into five major subtypes: 1b in 256 patients, 6a in 67 patients, 2a in 29 patients, 3a in 14 patients, and 3b in 13 patients. Using the E1 sequences obtained, along with those from other studies using samples from China, we inferred the HCV epidemic history by means of coalescence strategies. Five Bayesian skyline plots (BSPs) were estimated for the five subtypes. They concurrently highlighted the rapid growth in the HCVinfected population size from 1993 to 2000, followed by an abrupt slowing. Although flanked on both sides by variable population sizes, the plots showed distinct patterns of rapid HCV growth. Coincidently, 1993 to 2000 was a period when contaminated blood transfusions were common in China due to a procedural error in an officially encouraged plasma campaign. The abrupt slowing in 1998 to 2000 corresponded to the central government outlawing paid blood donations in 1998. Using a parametric model, the HCV population growth rates were estimated during 1993 to 2000. It was revealed that the 6a rate was the highest, followed by those of 1b, 2a, 3b, and 3a. Because these rates differed significantly (P < 1e؊9) from each other, they may help explain why 6a is increasingly prevalent in southern China and 1b is predominant nationwide. These rates are approximately 10-fold higher than those reported elsewhere. These findings suggested that during the plasma campaign, certain barriers to efficient viral transmission were removed, allowing wide HCV dissemination.

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Section: Discussionmentioning

confidence: 56%

The Current Hepatitis C Virus Prevalence in China May Have Resulted Mainly from an Officially Encouraged Plasma Campaign in the 1990s: a Coalescence Inference with Genetic Sequences

Lü

Tong

et al. 2013

J Virol

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“…In the study conducted by Zaller et al (2005), 20 % of Chinese respondents stated they could not contribute blood because they felt it would weaken their body or because they had poor health (i.e., loss of qi). In addition, traditionally the action of blood donation can be viewed as being disrespectful to one's ancestors because flesh and blood is inherited from parents (Shan et al 2002). Similar to the Chinese traditional beliefs, the Hmong believe blood is the source of strength and vitality for the body.…”

Section: Discussionmentioning

confidence: 99%

Engaging diverse populations about biospecimen donation for cancer research

et al. 2014

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Clinical research increasingly relies upon the availability of appropriate genetic materials; however, the proportion of biospecimens from racial/ethnic minority patients and healthy controls are underrepresented, which preclude equitable research across all patient groups for cancer treatment. National Cancer Institute-funded Community Network Program Centers in California, Florida, and New York collaborated with local community partners to conduct three independent formative research studies with diverse (African American, Asian American, Hispanic, and White) participants to explore their knowledge, attitudes, and beliefs about biobanking, and their experiences with the donation of biospecimens. Our findings demonstrated similarities in overall low knowledge and understanding about the use of biospecimens for research. This was exacerbated for nonEnglish speakers. Racial and ethnic groups differed with regard to a number of factors that are obstacles for participation, e.g., continuing medical mistrust (African Americans), lack of benefit (Hispanics), apprehension about the physical toll of donating (Vietnamese), usage of biospecimen for research (Hmong and Chinese), and suspicion of exploitation by corporate entities (Whites). However, participants uniformly reported general interest and willingness to participate in biobanking for altruistic purposes, particularly to benefit future generations. This interest was framed with a strong admonition that donations should be accompanied by transparency about study sponsorship and ownership, distribution and use of biospecimens, and study information that fit participants' backgrounds and experiences. This cross-cultural regional analysis offers significant insights into the similarities and variations in opinions and perceptions about biobanking and the collection of biospecimens for use in cancer research.

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“…Before 1998, there were a number of commercial blood donors living in rural areas of China. These blood donors sold blood to unlicensed private blood collection centers for payment (28). Some of these illegal centers used unsafe blood collection methods, such as the reuse of none-sterilized needles and reinfusion of pooled red blood cells from multiple donors, which could easily lead to HCV infection.…”

Section: Discussionmentioning

confidence: 99%

Hepatitis C virus infection in the general population: A large community-based study in Mianyang, West China

Zhou

et al. 2015

BST

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Blood banking in China

Cited by 137 publications

References 5 publications

The Current Hepatitis C Virus Prevalence in China May Have Resulted Mainly from an Officially Encouraged Plasma Campaign in the 1990s: a Coalescence Inference with Genetic Sequences

The Current Hepatitis C Virus Prevalence in China May Have Resulted Mainly from an Officially Encouraged Plasma Campaign in the 1990s: a Coalescence Inference with Genetic Sequences

Engaging diverse populations about biospecimen donation for cancer research

Hepatitis C virus infection in the general population: A large community-based study in Mianyang, West China

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