2017
DOI: 10.1002/ccr3.831
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Bleomycin‐induced flagellate hyperpigmentation

Abstract: Key Clinical MessageA 27‐year old male with Hodgkin's lymphoma was treated with combined chemotherapy that included bleomycin. He presented with pruritic erythematous, edematous linear lesions and was diagnosed to have flagellate hyperpigmentation, a rare side effect of bleomycin chemotherapy.

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Cited by 6 publications
(5 citation statements)
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“…Associated pruritus is treated with oral antihistamines and topical steroids. 9,10 In the present case, the patient was treated with topical clobetasol and oral antihistamine followed by symptomatic relief.…”
Section: Discussionmentioning
confidence: 81%
“…Associated pruritus is treated with oral antihistamines and topical steroids. 9,10 In the present case, the patient was treated with topical clobetasol and oral antihistamine followed by symptomatic relief.…”
Section: Discussionmentioning
confidence: 81%
“…Antihistamines and topical corticosteroids can be prescribed for the symptomatic treatment of pruritus and preventing microtrauma with scratching. 10,11 A cohesive or self-adhering bandage (eg, 3M Coban) is a type of bandage or wrap that adheres to itself but does not adhere well to other surfaces, like skin or hair. 3M Coban is commonly used as a wrap because it has a reliable hold and maintains compression without skin adhesion.…”
Section: Discussionmentioning
confidence: 99%
“…Antihistamines and topical corticosteroids can be prescribed for the symptomatic treatment of pruritus and preventing microtrauma with scratching. 10,11…”
Section: Discussionmentioning
confidence: 99%
“…Varias publicaciones han demostrado la eficacia de múltiples agentes esclerosantes para el tratamiento de las malformaciones linfáticas 5,[13][14][15][16] . La bleomicina es un antibiótico citotóxico antitumoral que exhibe un doble efecto: por un lado induce degradación del ADN y por otro presenta efecto esclerosante sobre el endotelio vascular, cualidad que le valió su uso intralesional en las ML 14,15 .…”
Section: Discussionunclassified
“…La bleomicina es un antibiótico citotóxico antitumoral que exhibe un doble efecto: por un lado induce degradación del ADN y por otro presenta efecto esclerosante sobre el endotelio vascular, cualidad que le valió su uso intralesional en las ML 14,15 . Es un agente esclerosante de baja potencia que presenta riesgos de complicaciones en piel como hiperpigmentación y sistémicas como fibrosis pulmonar 16 . Actualmente, en nuestro servicio reservamos su uso para lesiones en regiones donde el edema no es tolerable, como la vía aérea y malformaciones orbitarias.…”
Section: Discussionunclassified