Bleaching of hair by carbamide per hydrate

Abstract

We have observed 9 male patients with a generalized rash following the topical use of an over‐the‐counter antiparasitic powder (MOM®), containing ammoniated (11.2 g%) and metallic (4,2 g%) mercury, to treat phthiriasis (lice infestation). Primary and intensely erythemato‐exudative lesions of the pubic region and genitals were associated with inverted erythema of the upper inner thighs and, in severe cases, involvement of the face, neck, trunk and major flexures. Eruptions included exanthematic, papulo‐vesicular, purpuric and erythema‐multiforme‐like clinical pictures. 7 of the 9 cases presented with genera] malaise and pyrexia. A positive patch test reaction to ammoniated mercury was observed in all cases. There are probably 3 routes of powder exposure behind this type of rash: (i) direct skin contact; (ii) airborne skin contact; (iii) inhalation.

Pili Torti: A Feature of Numerous Congenital and Acquired Conditions

“…Associations between pili torti and numerous drugs were described in the literature [104][105][106][107][108].…”

“…Carbamide peroxide is a source of hydrogen peroxide, which affects the hair shaft by oxidation and decomposition of cysteine (which accounts for 20% of the amino acids of the hair keratin) as well as the formation of cysteic acid. Moreover, carbamide peroxide destroys the majority of the disulfide bridges of hair keratin [108].…”