Bladder stones associated with vesicovaginal fistula: A case report

Francisca,; Kholis, Khoirul; Palinrungi, Muhammad Asykar; Syahrir, Syakri; Syarif,

doi:10.1016/j.ijscr.2020.09.028

Cited by 7 publications

(26 citation statements)

References 15 publications

(24 reference statements)

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“…Controversy exists whether a two stage procedure (delayed repair, wherein stone removal is carried out followed by fistula repair after 3 months) is superior to concomitant repair. 2,6 Because of the advantages of concomitant repair in terms of patient outcomes, cost effectivity, and patient compliance, recent trend is toward using concomitant repair, as was the case in our patient. 13 This case is important not only for the clinical knowledge it imparts, but also because of its social association.…”

Section: Ofmentioning

confidence: 70%

“…Cystoscopy is preferred for definitive diagnosis, whereas X-ray-KUB, Ultrasonography (USG), CECT, dye tests (methylene blue), blood and urine analysis also aid in diagnosis. 2,3,9,12 Management is primarily surgical, addressing both the fistula and calculi. Stone management usually depends on size.…”

Section: Ofmentioning

confidence: 99%

“…Obstetric fistulas are abnormal connections between the genital tract and urinary/gastrointestinal tract, usually resulting in fecal or urinary incontinence 1 . A vesicovaginal fistula (VVF) is an abnormal communication between the bladder transitional epithelium and the vaginal squamous epithelium 2 . VVF is the most prevalent type of urogenital fistula and represents a devastating morbidity in gynecologic urology 3 .…”

Section: Introductionmentioning

confidence: 99%

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Vesicovaginal fistula associated with massive bladder calculi: An urogynecological case report

Sharma,

Karn,

Adhikari

et al. 2023

Clinical Case Reports

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Section: Ofmentioning

confidence: 70%

Section: Ofmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Vesicovaginal fistula associated with massive bladder calculi: An urogynecological case report

Sharma,

Karn,

Adhikari

et al. 2023

Clinical Case Reports

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“…It is noteworthy that causes of vesicocutaneous fistula are numerous and reported causes range from post-traumatic, bladder calculus, radiotherapy, post-operative, and bladder malignancy. [ 2 3 4 5 6 14 15 16 ] Other possible aetiologies of vesicoenteric or enterovesical fistula are benign conditions such as Meckel’s diverticulum and Crohn’s disease. [ 17 18 ]…”

Section: Discussionmentioning

confidence: 99%

Post-operative vesicoenterocutaneous fistula with multiple intestinal knotting: A case report

Khalid

Umar

Abdulwahab-Ahmed

et al. 2021

J West Afr Coll Surg

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Herein is a case of a 51-year-old farmer who presented to our facility with initial leakage of urine but later urine mixed with faeces from the lower abdomen after two previous abdominal surgeries. He had an open transvesical prostatectomy due to benign prostate enlargement complicated by leakage of urine from lower abdominal wall scar. A repeat surgical intervention to correct the urine leakage was followed by recurrence of urine leakage and later by leakage of feculent urine from the lower anterior abdominal wall. At our facility, he had exploratory laparotomy with manual unknotting of ileal loops, fistula tracts excision, resection, and end-to-end ileoileal anastomosis. The bladder wall was repaired with suprapubic cystostomy. Although the finding of asymptomatic multiple small bowel knotting was incidental in the index case, its timely management averted a sitting timed bomb that may lead to a diagnostic dilemma with catastrophic consequences.

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“…With the stable gastric pentadecapeptide BPC 157 therapy (for review, see, i.e., [1][2][3][4]), known to heal various both external [5][6][7][8] and internal [9,10] rat fistulas, we attempt to approach vesicovaginal fistula, continuous urine leaking through vagina, and bladder stones [11][12][13][14], as well as a possible therapy solution. Patients with a vesicovaginal fistula, the most common form of genitourinary fistula [11,14], typically present with continuous vaginal urine drainage [14], and smell of urine [15], and the degree of urinary incontinence is typically proportional to the size of the fistula tract [16], and likely presentation of the bladder stone that may further erode fistula as well.…”

Section: Introductionmentioning

confidence: 99%

Stable Gastric Pentadecapeptide BPC 157 Heals Established Vesicovaginal Fistula and Counteracts Stone Formation in Rats

et al. 2021

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With the stable gastric pentadecapeptide BPC 157 therapy known to heal various both external and internal rat fistulas, we attempt to approach vesicovaginal fistula, continuous urine leaking through vagina, bladder stones, and a possible therapy solution among rats with well-formed 2 week-fistulas (vaginal/vesical 4 mm large defects) started with delayed therapy. Subsequent control fistula course (the subsequent 1, 2, 4, and 6 weeks) since beginning revealed the failed healing, fistula leaking, adhesions, urinary leaking through vagina, failed epithelization, collagenization, granulation tissue and neovascularization, increased inflammation, and necrosis. Thereby, the later intervals revealed the persistent inability to sustain even minimal volume, vesical, and vaginal defects and stone formation at the end of the experiment (fistula-time day 56). BPC 157 therapy (10 µg/kg, 10 ng/kg, intraperitoneally once time daily or perorally in drinking water until sacrifice) was initiated with a considerable delay (at 2 weeks after fistula formation). Already within 1 week therapy, all BPC 157 regimens stopped urinary leaking through vagina, reversed the otherwise resistant poor healing course to the increased epithelization, collagenization, granulation tissue and neovascularization, decreased inflammation, and decreased necrosis. Thereby, at later intervals, all BPC 157 rats exhibited a five times larger volume that can be sustained before leaking as in healthy, vesical, and vaginal defects completely closed and no stone formation. Thus, macro/microscopic and functional recovery, and counteracted stone formation. Concluding, BPC 157 therapy’s beneficial effects resulted in healing and no stone formation, with µg- and ng-regimens, either given daily perorally in drinking water or intraperitoneally.

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Bladder stones associated with vesicovaginal fistula: A case report

Abstract: Highlights The existence of bladder stones is an uncommon condition that can cause vesico-vaginal fistulas (VVF). Almost all the cases resulted in giant bladder stones. Here, we report the uncommon case of a giant bladder stone causing VVF.

Cited by 7 publications

References 15 publications

Vesicovaginal fistula associated with massive bladder calculi: An urogynecological case report

Vesicovaginal fistula associated with massive bladder calculi: An urogynecological case report

Post-operative vesicoenterocutaneous fistula with multiple intestinal knotting: A case report

Stable Gastric Pentadecapeptide BPC 157 Heals Established Vesicovaginal Fistula and Counteracts Stone Formation in Rats

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