Bladder carcinoma in patients age 40 years or younger

Wan, Julian; Grossman, H. Barton

doi:10.1002/1097-0142(19890701)64:1<178::aid-cncr2820640130>3.0.co;2-b

Cited by 75 publications

(53 citation statements)

References 12 publications

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“…In addition, other studies reported decreased recurrence and progression rates in younger patients as well (28,29,30,31,32). As opposed to this, there are also other studies that showed no significant difference between age (33,34,35). In our study, percentage of stage T2 patients were found to be significantly higher in age group 65-80 and over 80.…”

Section: Discussioncontrasting

confidence: 81%

The Effect of Sex and Age Differences on Pathology Results in Primary Bladder Cancer Patients

Türk¹,

Ün²,

Ergani³

2017

uob

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Objective: Bladder cancer is more frequently seen in males, whereas prognosis is usually worse in female patients. Although many factors affect the prognosis of urothelial carcinoma of bladder have been proposed, the effect of female gender on the prognosis of bladder urothelial carcinoma is controversial. Several factors have been suggested regarding the effect of gender difference on the prognosis of bladder urothelial carcinoma. Materials and Methods: A retrospective study of 589 patients who underwent transurethral resection for the first time between January 2011 and January 2017 with preliminary diagnosis of bladder cancer was performed. Age, sex, tumor stage, histological subtype and tumor grade were evaluated in the study. Results: No significant difference was found between the sexes in terms of tumor stage (p=0.663). The rate of high-grade tumors was 48.6% (n=235) in males and 63% (n=41) in females and statistically significantly higher in females than males (p<0.041). As the age progressed, it was found that tumor stage and extend increased (p<0.0001). Tumor grade and histological subtype were not statistically significant in terms of age groups. Conclusion:In this study, newly diagnosed bladder tumor patients evaluated and revealed more in male gender. Furthermore, when evaluated in terms of age groups, it was shown that the stage and degree of the tumor increased as the age increased.

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Section: Discussioncontrasting

confidence: 81%

The Effect of Sex and Age Differences on Pathology Results in Primary Bladder Cancer Patients

Türk¹,

Ün²,

Ergani³

2017

uob

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“…Younger patients frequently present with lower grade and lower stage tumors than their elder counter parts (Wan, 1989). This is in contrast to the common belief that behaviour of cancer is more aggressive in younger age groups.…”

Section: Discussionmentioning

confidence: 67%

Urothelial Tumors of the Urinary Bladder in Manipur: A Histopathological Perspective

Laishram¹,

Kipgen²,

Laishram³

et al. 2012

Asian Pacific Journal of Cancer Prevention

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The study included 26 cases of transitional cell tumors of urinary bladder. The male to female ratio was 1.5: 1 and the ages ranged from 38 years to 73 years (medians of 60 and 64 years, respectively). Of the total, 14 (53.9%) cases were low grade, 9 (34.6%) were high grade, 2 (7.7%) were papillomas and 1 (3.9%) was a papillary urothelial neoplasm of low malignant potential (PUNLMP). Pathological staging showed that 14 (53.9%) of the cases were stage PTa, four (15.4%) PT1, and eight (30.9%) PT2. Some 18.2% of low grade tumors and 75% of high grade tumors were invasive to the detrusor muscle layer. Conclusion: Bladder cancer is an uncommon disease, transitional tumors being the only histological type observed. It was more common in males than females, with peak incidence in seventh decade. Most of the tumors were non-invasive (PTa) and invasion to the detrusor muscle layer was seen in more than half of the high grade tumors. There is a definite correlation between advancing tumor grade and muscle invasion.

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“…Transitional cancer of the bladder is a very rare malignancy in patients under 40 years (1-2.4% of all cancers) and among patients under 20 years it is extremely rare (0.1-0.4% of all bladder cancers) (ref. [3][4][5][6][7] ). According to a recent meta-analysis, only 103 bladder cancer patients under 20 years have been described.…”

Section: Discussionmentioning

confidence: 99%

High-grade urothelial bladder cancer in children: A case report and critical analysis of the literature

et al. 2016

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, Vladimir Student aBackground. Bladder cancer is relatively common in adults. In children, it is extremely rare and in the majority of cases, low grade, low stage urothelial cancers are found. Case report. We describe the diagnostic, therapeutic, and follow-up management of bladder cancer in a 3-year-old boy examined for painless hematuria. Transurethral resection of the tumor was performed and T1 high grade urothelial cancer with osseous metaplasia was found in definitive specimens. During the 2-year follow-up, there has been no recurrence. Typical characteristics of the most prevalent bladder tumors are presented. Conclusion. Despite its low incidence and low prevalence bladder cancer in children is a very serious condition which must not be missed in the differential diagnosis of hematuria or urinary tract infection. It is vital to differentiate urothelial cancer from hamartoma and nephrogenic adenoma and, particularly in osseous metaplasia, from sarcomatoid carcinoma. Especially in high-grade cancers, precise TUR of the tumor with a careful follow-up is essential to detect cancer recurrence and reduce progression.

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Bladder carcinoma in patients age 40 years or younger

Cited by 75 publications

References 12 publications

The Effect of Sex and Age Differences on Pathology Results in Primary Bladder Cancer Patients

The Effect of Sex and Age Differences on Pathology Results in Primary Bladder Cancer Patients

Urothelial Tumors of the Urinary Bladder in Manipur: A Histopathological Perspective

High-grade urothelial bladder cancer in children: A case report and critical analysis of the literature

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