“Black kidneys” in cattle—A lipofuscinosis

Winter, Hans

doi:10.1002/path.1700860137

Cited by 7 publications

(2 citation statements)

References 4 publications

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“…In some instances, it may be so intense thsat the kidneys appear dark blue [4]. This discoloration has led to the more common name "black kidney disease" [2,4,5]. Histopathology of "black kidneys" demonstrates no renal lesions and a preserved renal parenchyma.…”

Section: Introductionmentioning

confidence: 99%

Bovine Renal Lipofuscinosis in a Tanzanian Crossbred Yearling Male Calf: A Case Report

Masola

2024

Adv. Res.

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Aim: To report a rare case of bovine renal lipofuscinosis (BRL) that was encountered incidentally at necropsy. Presentation of the Case: In June 2023 an yearling male calf was found dead in one of the dairy cattle farms in Mbeya city, Tanzania; after being sick for about a week. The owner requested a necropsy service to establish the cause of the death of the animal. Necropsy revealed significant gross pathological changes in a liver that was cooked-like and shrunken, with flabby consistence and large pale necrotic foci. Furthermore, dark blue discoloration of both kidneys with normal morphology was evident. Based on the history and gross pathological findings, the animal was diagnosed to have died from acute hepatitis. Differential diagnosis for kidney discoloration included hemachromatosis, renal hemosiderosis, BRL, and melanotic renal cell carcinoma (MRCC). After ruling out hemachromatosis, renal hemosiderosis and MRCC in the list of possible causes of kidney discoloration based on the lack of gross pathological findings, particularly hepatic fibrosis, pallor, and a mass of tumor tissue in the kidneys that are characteristic of hemachromatosis, renal hemosiderosis and MRCC, respectively; the cause of kidney discoloration was diagnosed as BRL. Discussion: In this necropsy, the history and gross pathology suggested that the animal’s death could be attributed to acute liver failure, which is one of the sequelae of acute hepatitis. Kidney discoloration was not considered an attribute factor to the animal’s death because, with the exception of discoloration, the kidneys did not have gross pathological changes. Moreover, to date there has been no report of a clinical disease in cattle associated with BRL. However, BRL is an important disorder because it leads to condemnation of the affected kidneys as unfit for human consumption. Conclusion: The case of BRL reported here was an incidental finding at necropsy, and is not associated with the death of the animal.

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Section: Introductionmentioning

confidence: 99%

Bovine Renal Lipofuscinosis in a Tanzanian Crossbred Yearling Male Calf: A Case Report

Masola

2024

Adv. Res.

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“…The accumulation is associated with brown to black discolouration of the kidneys, which are condemned as unfit for human consumption. This discolouration has given rise to the more common name "black kidney disease" [ 1 ]. Although known for more than 100 years, only a few studies have been done on this disorder and mostly focusing on the nature of the pigment [ 2 - 5 ].…”

Section: Introductionmentioning

confidence: 99%

Bovine renal lipofuscinosis: Prevalence, genetics and impact on milk production and weight at slaughter in Danish cattle

et al. 2009

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Background: Bovine renal lipofuscinosis (BRL) is an incidental finding in cattle at slaughter. Condemnation of the kidneys as unfit for human consumption was until recently considered the only implication of BRL. Recent studies have indicated a negative influence on the health of affected animals. The present study investigated the prevalence, genetics and effect of BRL on milk yield and weight at slaughter.

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The Urinary System

Maxie¹

1985

Pathology of Domestic Animals

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“Black kidneys” in cattle—A lipofuscinosis

Cited by 7 publications

References 4 publications

Bovine Renal Lipofuscinosis in a Tanzanian Crossbred Yearling Male Calf: A Case Report

Bovine Renal Lipofuscinosis in a Tanzanian Crossbred Yearling Male Calf: A Case Report

Bovine renal lipofuscinosis: Prevalence, genetics and impact on milk production and weight at slaughter in Danish cattle

The Urinary System

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