2010
DOI: 10.1590/s0102-695x2010005000051
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Abstract: RESUMO:Humulus lupulus L., Cannabaceae, é usada como sedativo e ansiolítico na medicina popular. O método de HPLC-DAD-ESI-MS n representa uma ferramenta poderosa para a análise de produtos naturais, desde que ela fornece o espectro de UV e informações estruturais sobre os constituintes da mistura. O objetivo deste trabalho foi o de caracterizar os constituintes encontrados no extrato hidroalcoólico. Os constituintes 1-9 foram tentativamente caracterizados através do UV/DAD e ionização por electrospray (MS/MS) … Show more

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Cited by 18 publications
(11 citation statements)
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References 56 publications
(67 reference statements)
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“…Nevertheless, enhanced activity of sugar transporter genes such as sugar transport 13, SWEET family of sugar transporters, ATP binding cassette (ABC) transporters, plastidic ATP/ADP-transporter underscoring the exogenous supply of sugars and energy to LG tissues, corroborating the previous finding that sucrose serves as an excellent and ideal source for secondary metabolite production in glandular trichomes [44]. The gene family (tropinone reductases) regulating the tropane alkaloid biosynthesis [45] were notably highly expressed in LG compared to BR and LF, which indeed was inconsistent with the previous result which demonstrated the absence of alkaloids in hop extracts [46]. In this context, the candidate substrate or function of tropinone reductases can open novel directions for future investigation in hop.…”
Section: The Differential Expression Patterns Of Unigenes In Differensupporting
confidence: 45%
“…Nevertheless, enhanced activity of sugar transporter genes such as sugar transport 13, SWEET family of sugar transporters, ATP binding cassette (ABC) transporters, plastidic ATP/ADP-transporter underscoring the exogenous supply of sugars and energy to LG tissues, corroborating the previous finding that sucrose serves as an excellent and ideal source for secondary metabolite production in glandular trichomes [44]. The gene family (tropinone reductases) regulating the tropane alkaloid biosynthesis [45] were notably highly expressed in LG compared to BR and LF, which indeed was inconsistent with the previous result which demonstrated the absence of alkaloids in hop extracts [46]. In this context, the candidate substrate or function of tropinone reductases can open novel directions for future investigation in hop.…”
Section: The Differential Expression Patterns Of Unigenes In Differensupporting
confidence: 45%
“…Today, a wide range of the preparations containing hops extracts or hops-derived products are available on the market, in particular for use in the phytotherapy of sleep disorders or pain relief and in postmenopausal therapy. Increasing evidence reveals that the so-called hops bitter acids, which represent up to 30% of the total lupulin content of hops, prenylflavonoids and xanthohumol exhibit interesting effects on human health [1][2][3][4]. Also, it is well-known that hops and the brewing industry are strongly linked.…”
Section: Introductionmentioning
confidence: 99%
“…Cultivation of hops is climatically and ecologically appropriate in temperate regions of the world. 1,2 The major prenylated chalcone of hop cones is xanthohumol, which has important pharmacological activities, such as antiproliferative, anti-inflammatory, antioxidant, pro-apoptotic, antibacterial, and anti-adhesive effects. 3 Especially, the anticancer properties of this compound were found in recent studies.…”
mentioning
confidence: 99%