Bitemporal peripapillary hemorrhages: Toxic-ischemic optic neuropathy caused by ethanol and cocaine abuse

Matas, Raquel Burggraaf-Sánchez de las; Sandino-Pérez, M.L.

doi:10.1016/j.ajoc.2022.101374

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“…Our patient presented with findings most supportive of AION and PION in the setting of heroin overdose. Ischemic optic neuropathy has been reported in cases with methamphetamine use [22] , amlodipine overdose [23] , and cocaine use [24] . But there is no reported case of ION in the setting of heroin / opioid use.…”

Section: Discussionmentioning

confidence: 99%

Acute ischemic optic neuropathy in a case of heroin overdose

Lakhani

Balar

Tarabishy

et al. 2022

Radiology Case Reports

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Section: Discussionmentioning

confidence: 99%

Acute ischemic optic neuropathy in a case of heroin overdose

Lakhani

Balar

Tarabishy

et al. 2022

Radiology Case Reports

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Protective Effect and Mechanism of DHQ On Ethanol-induced Gastric Mucosal Injury in GES-1 Cells

Hu,

Wang,

et al. 2023

AJST

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It is reported that the incidence of gastric mucosal injury diseases is very high in the world, among which ethanol is one of the most important predisposing factors. In this study, DHQ effectively inhibited ethanol-induced apoptosis of GES-1 cells in a concentration-dependent manner. DHQ can down-regulate the expression of various pro-apoptotic proteins and up-regulate the expression of anti-apoptotic proteins, which may be related to the activation of mitochondrial apoptosis pathway. Therefore, DHQ can protect gastric mucosal epithelial cells to a certain extent, and finally achieve the protective effect of protecting gastric mucosa. Our study provides new insights for the prevention and treatment of gastric mucosal injury diseases, and DHQ can be used as a new therapeutic drug.

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Bitemporal peripapillary hemorrhages: Toxic-ischemic optic neuropathy caused by ethanol and cocaine abuse

Cited by 2 publications

References 2 publications

Acute ischemic optic neuropathy in a case of heroin overdose

Acute ischemic optic neuropathy in a case of heroin overdose

Protective Effect and Mechanism of DHQ On Ethanol-induced Gastric Mucosal Injury in GES-1 Cells

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