Protective Effect and Mechanism of DHQ On Ethanol-induced Gastric Mucosal Injury in GES-1 Cells
Kun Hu,
Qianwen Wang,
Siqi Yi
et al.
Abstract:It is reported that the incidence of gastric mucosal injury diseases is very high in the world, among which ethanol is one of the most important predisposing factors. In this study, DHQ effectively inhibited ethanol-induced apoptosis of GES-1 cells in a concentration-dependent manner. DHQ can down-regulate the expression of various pro-apoptotic proteins and up-regulate the expression of anti-apoptotic proteins, which may be related to the activation of mitochondrial apoptosis pathway. Therefore, DHQ can prote… Show more
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