Bisphenol A and adiposity measures in peripubertal boys from the INMA-Granada cohort

Bisphenol A promotes macrophage proinflammatory subtype polarization via upregulation of IRF5 expression in vitro

“…Geens et al estimated the levels of human exposure to BPA to be in the range of 0.1-5 μg/kg BW/d from the dietary and nondietary route (Geens et al 2012). Population data show that BPA can be detected in multiple biological samples from more than 90% of humans (Mustieles et al, 2019;LaKind and Naiman, 2015;Vandenberg et al, 2010). Increasing evidence reveals that human exposure to low concentration BPA is closely associated with inflammation and impairment of immune functions (Li et al, 2018;Malaisé et al, 2018;Rogers et al, 2017;Zbucka-Kretowska et al, 2017;Luo et al,2016;Gostner et al,, 2015;Rogers et al, 2013).…”

Relationship between endocrine disruptors and obesity with a focus on bisphenol A: a narrative review

“…The results have shown that BPA could exert an obesogenic effect by increasing the risk of "overweight/obesity" and abdominal obesity. 9 In vivo studies endorse these epidemiological observations and suggest the influence of the EDCs on fatty mass development, mainly when exposure occurred in the prenatal phase. [10][11][12] Early exposure demonstrated that EDCs can indirectly act through changes in maternal endocrine status (i.e.…”

New insights on the effects of endocrine-disrupting chemicals on children

“…A relationship between gestational levels of BPA and central adiposity during early childhood was found. 66 Urinary BPA levels were associated with a greater risk of central obesity 67 and a positive association of dietary exposure to BPA and total bisphenols with being overweight/obese was found in adolescent girls. 68 …”