Bispectral analysis of the electroencephalogram during induction of anesthesia may predict hemodynamic responses to laryngoscopy and intubation

Kearse, Lee A.; Manberg, Paul J.; deBros, F.; Chamoun, Nassib G.; Sinai, V.

doi:10.1016/0013-4694(94)90091-4

Cited by 88 publications

(19 citation statements)

References 21 publications

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“…More complex processing of EEG signals such as bispectral analysis have been used in this setting, but lack multiple channel discrimination achieved using raw data. 36,37 Our EEG results are similar to those reported by others, 2,38,39 showing increases in beta power with low dose infusions, and extend these observations to higher plasma concentrations of propofol, where marked increases in delta and alpha frequency power occur.…”

Section: Electroencephalographic Effectssupporting

confidence: 90%

Autonomic circulatory and cerebrocortical responses during increasing depth of propofol sedation/hypnosis in humans

Lafreniere

Milne

Brunet

et al. 2000

Can J Anesth/J Can Anesth

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Purpose: To describe the relative effects of graded central nervous system (CNS) depression, using increasing propofol infusion rates, on neurovegetative brainstem-mediated circulatory control mechanisms and higher cortical activity in healthy humans.Methods: Propofol was administered using an infusion scheme designed to achieve three target blood concentrations in ten healthy volunteers. Blood propofol concentrations and sedation scores were determined at baseline, during the three propofol infusion levels, and 30 min into the recovery period. Electroencephalographic (EEG) power was measured in three frequency bands to quantify cortical activity, and autonomic heart rate control was quantified using spontaneous baroreflex assessment and power spectral analysis of pulse interval. Results: Sedation scores closely paralleled propofol blood concentrations (0, 0.53 ± 0.34, 1.24 ± 0.21, 3.11 ± 0.80, and 0.96 ± 0.42 µg·mL -1 at baseline, three infusion levels and recovery respectively), and all subjects were unconscious at the deepest level. Indices of autonomic heart rate control were decreased only at the deepest levels of CNS depression, while EEG effects were apparent at all propofol infusion rates. These EEG effects were frequency specific, with power in the beta band being affected at light levels of sedation, and alpha and delta power altered at deeper levels. Conclusions: The results of this study support a relative preservation of neurovegetative circulatory control mechanisms during the early stages of CNS depression using gradually increasing rates of infusion of propofol. Indices of circulatory control did not reliably reflect depth of sedation.Objectif : Décrire les effets relatifs d'une dépression graduée du système nerveux central (SNC) sur les mécanismes d'origine centrale du contrôle neurovégétatif de la circulation, et l'activité corticale supérieure chez des humains sains, en utilisant des perfusions de propofol à vitesses croissantes. Méthode : Le propofol a été administré, chez dix volontaires en santé, selon un schéma de perfusion conçu pour atteindre trois concentrations sanguines cibles. Les concentrations sanguines de propofol et les scores de sédation ont été déterminés au départ, pendant les trois régimes de perfusion de propofol et à 30 min pendant la récupéra-tion. La puissance électroencéphalographique (EEG) a été mesurée selon trois bandes fréquentielles pour quantifier l'activité corticale, et le contrôle autonome de la fréquence cardiaque a été mesuré à l'aide d'une évaluation baroréflexe spontanée et de l'analyse spectrale de la puissance de l'intervalle pulsé.Résultats : Les scores de sédation ont présenté un étroit parallélisme avec les concentrations sanguines de propofol (0; 0,53 ± 0,34, 1,24 ± 0,21; 3,11 ± 0,80, et 0,96 ± 0,42 µg·mL -1 au début, pendant les trois perfusions et la récupération, respectivement), et tous les sujets ont connu un profond sommeil. Les indices de contrôle autonome de la fréquence cardiaque ont diminué seulement au moment de la plus profonde dépression d...

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Section: Electroencephalographic Effectssupporting

confidence: 90%

Autonomic circulatory and cerebrocortical responses during increasing depth of propofol sedation/hypnosis in humans

Lafreniere

Milne

Brunet

et al. 2000

Can J Anesth/J Can Anesth

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“…BIS is reported to respond to laryngoscopy and intubation, 10 to movement with LMA insertion, 11 to intubation, 12 or to skin incision. 13 However, in this study, the AAI increased significantly in response to LMA insertion and skin incision, while the BIS did not.…”

Section: Me Et Th Ho Od Ds Smentioning

confidence: 99%

L’index «A-line ARX» peut être un détecteur plus sensible du réveil que l’index bispectral pendant l’anesthésie avec propofol-fentanyl-protoxyde d’azote: une recherche préliminaire

Nishiyama

Hanaoka

2004

Can J Anesth/J Can Anesth

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“…Complementarmente, determina os componentes tanto do EEG linear, também chamado de espectro de potência, os quais compreendem freqüência e amplitude das ondas, como do não linear que incluem a fase e ritmo destas. Além disso, quantifica o nível de sincronização dos sinais eletroencefalográficos (interação das fases de interfreqüência), através do exame dos componentes de freqüência fundamental e a sua conexão com o padrão rítmico associado à análise estatística de ordem superior (KEARSE et al, 1994;SEBEL et al, 1997).…”

Section: íNdice Biespectral (Bis)unclassified

Monitoramento do índice biespectral em cães

Guerrero¹,

Nunes²

2003

Sem. Ci. Agr.

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ResumoAtualmente, na tentativa de complementar a monitoração anestésica dos pacientes, utilizam-se a análise de variáveis clínicas ou técnicas eletrofisiológicas. Entretanto, é difícil utilizá-las para se obterem informações determinantes e uniformes dos planos anestésicos, para todos os agentes anestésicos. Conseqüentemente, foi desenvolvido, através de múltiplas investigações e avanços tecnológicos, o que se pode definir como monitor de profundidade anestésica, o monitor de índice biespectral (BIS). Desta forma, objetivou-se com este trabalho, fornecer informações a respeito do monitoramento do BIS, em cães. Além disso, foram abordadas considerações relativas ao seu desenvolvimento, função, manipulação adequada e aspectos referentes ao comportamento desta variável quando usada com diferentes agentes anestésicos. Palavras-chave: Anestesia, índice biespectral, eletroencefalograma. AbstractNowadays, in the attempt to complement anesthetic patient monitoring, clinical variables analyzes and electrophysiologic techniques are being used. However it is difficult to obtain determinant and uniform information about anesthetic plans for all types of anesthetic agents. Consequently, a monitor of anesthetic depth known as bispectral index (BIS) has been developed through multiple studies and technical advances. Therefor, this review aimed to provide information about the BIS in dogs. Additionally, considerations related to its development, function and proper manipulation were made, and also behavior aspects of this parameter when applied in different anesthetics. Key words: Anesthesia, bispectral Index, electroencephalogram.1 Pós-graduanda em Cirurgia Veterinária -Área de Concentração em Cirurgia -Faculdade de Ciências Agrárias e Veterinárias, UNESP, Câmpus de Jaboticabal, SP. 2 Professor Doutor, Depto. de Clínica e Cirurgia Veterinária. Faculdade de Ciências Agrárias e Veterinárias, UNESP, CEP: 14884-900, Jaboticabal, SP. E-mail: newton@fcav.unesp.br * Autor para correspondência. IntroduçãoDurante a evolução da Anestesiologia, um dos principais objetivos tem sido avaliar a profundidade anestésica na qual o paciente se encontra. Os primeiros parâmetros descritos por Snow, em 1847 referem-se a 5 estágios na anestesia com o éter. Mais tarde, Guedel reafirmaria e definiria melhor estes estágios, os quais são utilizados até hoje pelos anestesistas, como guia para determinar a profundidade da anestesia.Atualmente, na tentativa de complementar esta avaliação, utilizam-se a análise de variáveis clínicas ou técnicas eletrofisiológicas. Alguns destes parâmetros incluem freqüências respiratória e COMUNICAÇÕES / COMMUNICATIONS

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Bispectral analysis of the electroencephalogram during induction of anesthesia may predict hemodynamic responses to laryngoscopy and intubation

Cited by 88 publications

References 21 publications

Autonomic circulatory and cerebrocortical responses during increasing depth of propofol sedation/hypnosis in humans

Autonomic circulatory and cerebrocortical responses during increasing depth of propofol sedation/hypnosis in humans

L’index «A-line ARX» peut être un détecteur plus sensible du réveil que l’index bispectral pendant l’anesthésie avec propofol-fentanyl-protoxyde d’azote: une recherche préliminaire

Monitoramento do índice biespectral em cães

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