“…The dipolar reagents can be generated by the dehydrogenation of araldehyde hydrazones and araldoximes with lead tetraacetate , mercury acetate , 1‐chlorobenzotriazole , chloramine‐T (CAT) , etc. In fact, we have reported novel oxo‐linked bis heterocycles by 1,3‐dipolar cycloaddition of dipolar reagents viz ., TosMIC, diazomethane, nitrile imines and nitrile oxides to symmetrical and unsymmetrical bischalcones . It is well known that the combination of two or more heterocycles in a single molecule could afford a novel entity with increased bioactivities .…”