Birds as Models of Aging in Biomedical Research

Austad, Steven N.

doi:10.1093/ilar.38.3.137

Cited by 31 publications

(11 citation statements)

References 28 publications

(23 reference statements)

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“…Although this parrot is not a threatened species, it is widely used in captivity and, therefore, is commonly removed from nature. This species can be used as a model for longevity due to its high relative oxygen consumption, high glucose level, and an above average body temperature [17]. A critically endangered parrot species, the Orange-bellied parrot (Neophema chrysogaster), from Australia and south-western Tasmania, was also genetically analyzed using microsatellite data [9].…”

Section: Resultsmentioning

confidence: 99%

A Review of Microsatellite Markers and their Application on Genetic Diversity Studies in Parrots

Presti¹,

Wasko²

2014

OJGen

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The ability of a population to adapt to a changing environment depends on its genetic variation. Thus, the study of genetic diversity within and among species or populations is especially important on conservation biology scopes. One way to assess the genetic diversity is through the use of microsatellite molecular markers. Microsatellites have been widely used to answer population genetics issues as gene flow, parentage, and population structure, mostly resulting in data on the distribution of genetic variability within and among natural populations, which are essential for ex situ and in situ conservation procedures. As the Psittacidae family comprehends one of the birds group with the largest number of endangered species, studies that aim to investigate the genetic diversity of these animals may support their conservation. This article is a review of genetic data on parrots, through the use of microsatellite markers, that have been published since 2004.

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Section: Resultsmentioning

confidence: 99%

A Review of Microsatellite Markers and their Application on Genetic Diversity Studies in Parrots

Presti¹,

Wasko²

2014

OJGen

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“…The budgerigar, Melopsittacus undulatus, is a parakeet that is believed to be native to Australia and is a popular pet in developed countries. The budgie, as it is commonly known, has exceptional longevity, high relative oxygen consumption, high glucose level, and an above average body temperature, which makes it a useful animal model for ageing (Austad 1997). These characteristics should decrease the maximum life span of the budgie, yet they are able to live for more than 20 years.…”

Section: Characteristics Of Microsatellite Loci Isolated From Melopsimentioning

confidence: 99%

“…The use of the budgerigar as an animal model for longevity (Austad 1997) as well as for determining its relationship with other Psittaciformes (Dyke & Mayr 1999; deKloet & deKloet 2006), however, remains limited because of the paucity of genetic information. There is very little known genetic information about the budgerigar, including DNA markers that are specific for its genome.…”

Section: Characteristics Of Microsatellite Loci Isolated From Melopsimentioning

confidence: 99%

Isolation and characterization of microsatellite markers from the budgerigar, Melopsittacus undulatus

Kamara

Geng

et al. 2006

Molecular Ecology Notes

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The budgerigar, Melopsittacus undulatus, belongs to a group of birds that are among the most common captive‐held avian species that are also most threatened. Budgies are also a valuable resource as model species for many important vertebrate characteristics including auditory and ageing. Several microsatellite‐enriched genomic libraries were developed using standard protocols. Twelve of 20 primer pairs developed from microsatellite‐containing sequences were codominant and polymorphic when tested on 21 birds from three different states. The number of alleles detected ranged from two to four, with the expected and observed heterozygosities ranging from 0.09 to 0.61 and from 0.00 to 0.85, respectively. The genomic libraries and the primers described here will be useful in characterizing budgies.

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“…Although a less commonly used species, pigeons (Columba livia) are used in biomedical research for studies of vision, cognition, behavior, neural science, and spatial orientation. 1,16,17,20 Research at our institution is focused on neurobiology and homing abilities. Traditionally, research pigeons have been maintained in standard laboratory cages, modified flight rooms, or modified outdoor lofts, with recommended floor space according to the Guide for the Care and Use of Laboratory Animals of 0.8 square feet per animal.…”

mentioning

confidence: 99%