Bipolar plasma kinetic enucleation of non-muscle-invasive bladder cancer: Initial experience with a novel technique

Abo-Taleb, Ahmed; Kandeel, Wael; Elmohamady, Basheer; Noureldin, Yasser A.; El‐Shaer, Waleed; Sebaey, Ahmed

doi:10.1016/j.aju.2017.07.001

Cited by 7 publications

(4 citation statements)

References 14 publications

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“…The high-frequency current forms an electromagnetic field through conductive normal saline, which is finally converted into macromolecules in target tissue decomposition organisms. 30 PC and PKRBT are two surgical methods that can effectively preserve the bladder function of patients while achieving radical resection of tumor tissues. This study mainly observes the clinical efficacy of these two surgical modalities in patients with BC.…”

Section: Discussionmentioning

confidence: 99%

Clinical Efficacy and Quality of Life Assessment of Partial Cystectomy and Plasmakinetic Transurethral Resection of Tumor in Bladder Cancer Patients

Li¹,

Wang²,

Zhi-hu³

2022

CMAR

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Objective Bladder cancer is a common malignant tumor of the urinary system, with an incidence ranking the first in the urinary system. Without timely and effective treatment, the tumor may spread to other parts of the body. Traditional partial cystectomy (PC) and plasmakinetic transurethral resection of bladder tumor (PKRBT) are common surgical methods for superficial bladder cancer (SBC). This study aims to clarify the clinical efficacy of bladder carcinoma (BC) patients treated by either PC or PKRBT and their effects on the quality of life (QOL) of patients. Methods A total of 142 patients with SBC treated in Wenzhou Central Hospital and Bei da huang Industry Group General Hospital from March 2018 to June 2020 were analyzed retrospectively. According to the surgical method, patients undergoing PKRBT were included in the research group (n = 74) while those treated by PC were included in the control group (n = 69). Surgical indicators (intraoperative blood loss, IBL; operating time, OT; bladder irrigation time; catheter retention time; length of hospital stay, LOS), postoperative complication rate, and one-year recurrence rate were compared between the two groups. Besides, the levels of inflammatory factors [tumor necrosis factor (TNF)-α, interleukin (IL)-6, IL-8, IL-10], psychological and emotional scores (Self-Rating Anxiety Scale, SAS; Self-Rating Depression Scale, SDS), and living conditions (Pittsburgh Sleep Quality Index, PSQI) before and after treatment were compared. Results Compared with the control group, patients in the research group had 1) less IBL, less time of OT, bladder irrigation and indwelling catheter time, as well as shorter postoperative LOS; 2) lower contents of inflammatory factors TNF-α, IL-6 and IL-8, and higher IL-10; 3) lower SAS and SDS scores and higher PSQI; and 4) fewer postoperative complications and lower one-year recurrence rate. Conclusion Compared with PC, PKRBT contributes to higher efficacy and better postoperative QOL in patients SBC.

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Section: Discussionmentioning

confidence: 99%

Clinical Efficacy and Quality of Life Assessment of Partial Cystectomy and Plasmakinetic Transurethral Resection of Tumor in Bladder Cancer Patients

Li¹,

Wang²,

Zhi-hu³

2022

CMAR

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“…3 Over the past 2 decades, many studies have reported on the clinical utility of ERBT, and evidence is increasingly available on safety, recurrence rate, and ERBT specimen quality. 4–14,18–23…”

Section: Discussionmentioning

confidence: 99%

Clinical Significance of Horizontal and Vertical Margin of En Bloc Resection for Nonmuscle Invasive Bladder Cancer

et al. 2021

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Purpose:The primary advantage of en bloc resection of bladder tumors is to provide better diagnostic accuracy. However, the clinical significance of horizontal and vertical margin has not been demonstrated. We evaluated the clinical importance of surgical margins in patients who underwent en bloc resection of bladder tumors.Materials and Methods:We retrospectively analyzed the records of 140 consecutive patients who underwent en bloc resection of bladder tumors for nonmuscle invasive bladder cancer. We analyzed perioperative and oncological outcome, and compared patient demographics and recurrence-free survival for horizontal findings. The relationship between surgical margin and second transurethral resection outcome in pT1 bladder cancer was also analyzed.Results:Mean tumor diameter was 17.2±9.8 mm. Pathological stages were 93 cases in pTa and 47 cases in pT1. Diagnostic rates for the horizontal and vertical margins were 63% and 99%, respectively. The rates of sessile, carcinoma in situ, high grade, and pT1 tumors were significantly higher in the horizontal margin positive group (41) than in the negative group (47). There was no significant difference in 2-year recurrence-free survival based on horizontal margin findings (negative: 72.4%, positive: 75.4%, p=0.87). A second transurethral resection was performed in 31 of the 47 pT1 patients; pT1 residue was seen only in vertical margin positive cases, and 5 pTa/pTis residues at the transurethral resection scar were seen in 15 horizontal margin positive patients.Conclusions:Horizontal margin positive findings were not associated with recurrence-free survival, but careful assessment is warranted regarding residue at the original site. A second transurethral resection should be considered in patients with horizontal and vertical margin positive pT1 bladder cancer.

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“…Such values made the En-bloc resection in majority of cases possible (according to the guidelines recommendations ̶ up to 3 cm). In more than 55% cases the tumor lesions were mainly located on the side walls [19]. In two studies data regarding the average resignation of the detected tumors were not presented (Table 1).…”

Section: Fig 1 Technique Of En-bloc Resection (Clinical Case) Discumentioning

confidence: 95%

Analysis of Endourological Treatment Techniques of Urinary Bladder Tumors

Vladanov¹,

Plesacov²,

Ghicavii³

2021

interconf

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Transurethral resection is very important not only for diagnosis and treatment of NMIBC, but also for its management. The application field of transurethral resection includes establishing histological diagnosis, determination of prognostic factors including the tumor stage, complete resection of all detected tumors of urinary bladder. Transurethral resection of bladder tumor (TURBT) is the standard technique for the diagnosis and treatment of non-muscle invasive bladder cancer. This method has also some limitations. One of the limitations is the insufficient assessment of the resection depth. It leads to the necessity of intravesical tumor fragmentation, but its disadvantage is that it limits the histopathological evaluation. In order to improve the treatment outcome for patients with non-muscular invasive bladder tumors, several new techniques such as En-bloc resection were proposed.

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Bipolar plasma kinetic enucleation of non-muscle-invasive bladder cancer: Initial experience with a novel technique

Cited by 7 publications

References 14 publications

Clinical Efficacy and Quality of Life Assessment of Partial Cystectomy and Plasmakinetic Transurethral Resection of Tumor in Bladder Cancer Patients

Clinical Efficacy and Quality of Life Assessment of Partial Cystectomy and Plasmakinetic Transurethral Resection of Tumor in Bladder Cancer Patients

Clinical Significance of Horizontal and Vertical Margin of En Bloc Resection for Nonmuscle Invasive Bladder Cancer

Analysis of Endourological Treatment Techniques of Urinary Bladder Tumors

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