Bipolar disorder in children and adolescents: international perspective on epidemiology and phenomenology

Soutullo, César; Chang, Kiki; Díez-Suárez, Azucena; Quintana, Ana Figueroa; Escamilla-Canales, Inmaculada; Rapado-Castro, Marta; Ortuño, Felipe

doi:10.1111/j.1399-5618.2005.00262.x

Cited by 113 publications

(75 citation statements)

References 51 publications

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“…Clinical samples have revealed prevalence estimates ranging from 1.7 to 4.2%. 39 In Brazil, a study found 36 subjects with pediatric BD (PBD; , 15 years old) in a sample of 500 patients from a child and adolescent psychopharmacology outpatient program. 40 These data combined suggest the prevalence of BD type I and II in children and adolescents to be between 0.1 to 2.5%.…”

Section: Epidemiologymentioning

confidence: 99%

Mood disorders in childhood and adolescence

Rocha

Zeni

Caetano

et al. 2013

Rev. Bras. Psiquiatr.

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The identification and treatment of mood disorders in children and adolescents has grown over the last decades. Major depression is one of the most common and debilitating disorders worldwide, imposing a massive burden to the youth population. Bipolar disorder is being increasingly recognized as having its roots early in life, and its presentation during childhood and adolescence has been submitted to extensive research. This review aims to highlight clinical aspects of the current knowledge on mood disorders in the pediatric population, presenting updated information on epidemiology, diagnostic procedures, and management strategies. Limitations of available evidence and future directions of research in the field are also discussed.

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Section: Epidemiologymentioning

confidence: 99%

Mood disorders in childhood and adolescence

Rocha

Zeni

Caetano

et al. 2013

Rev. Bras. Psiquiatr.

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“…Tanı dağılımına bakıldığında, bir çocuk ve ergen psikiyatri polikliniğinde BPB tanı-sı alanlar üzerinde yapılan bir çalışmada BPB-I için %48, BPB-II için %16, başka türlü adlandırılamayan BPB (BPB-BTA) için %36 bulunmuştur (Soutullo 2003). Son dö-nemde yapılan bir çalışmada ise BPB tanısı alanların %44.7'si BPB-I, %5.3'ü BPB-II ve %50'si BPB-BTA olarak ayrıştırılmıştır (Escamilla ve ark.…”

Section: Poliklinik öRneklemlerindeunclassified

“…Axelson ve arkadaşlarının (2006), hastanede yatan ve/veya ayaktan takipli 7-18 yaş arası 438 bipolar çocuk ve ergen üzerinde yaptığı araştırmada, hastalığın başlama yaşı sırasıyla BPB-I için 9.5 (± 4.0) yıl, BPB-II için 11.2 (± 3.4) yıl ve BPB-BTA için 8.7 (± 3.5) yıl olarak bulunmuştur. Ancak, hastaların belirtilerinin başlama-sından ortalama 4.4 yıl sonra tanı aldıkları belirlenmiştir (Soutullo 2003). Başka bir çalışmada ise BPB tedavisi alan çocuk ve ergenlerin yarısından fazlasının belirtilerin ortaya çıkmasından en az 5 yıl sonra bir tanı aldığı bulunmuştur (Marchand ve ark.…”

Section: Başlama Yaşıunclassified

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Epidemiology in Pediatric Bipolar Disorder

Mutlu¹,

Doksat²,

Erdoğan³

2015

Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychia

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ÖzetÇocuk ve ergenlerde bipolar bozukluk tanısı giderek artış göstermektedir. Çocuk ve ergen popülas-yonunda intihar girişiminde bulunanların önemli bir oranının bipolar bozukluğu olanlarda ortaya çıkıyor olması, bu hastalığın tanı ve tedavisini daha da önemli kılmaktadır. Özellikle ergenlik dönemi öncesi örneklemlerde açık tanı ölçütlerinin olmaması ve değerlendirmelerin belirtilere dayanılarak yapılmasından dolayı yanlış biçimde bipolar bozukluk tanısı konduğu ve yaygınlık oranlarının olduğundan fazla saptandığına dair endişeler vardır. Bunlardan ötürü, çocuk ve ergen bipolar bozukluğunun yaygınlığı konusundaki veriler hem farklılık göstermekte hem de tartışılmaktadır. Bu derleme çalışmasında, bipolar bozukluğun yaygınlığı toplum, poliklinik ve yatan hasta örneklemin-de literatür gözden geçirilmiştir. AbstractChildhood and adolescent bipolar disorder diagnosis has been increasing recently. Since studies evaluating attempted suicide rates in children and adolescents have shown bipolarity to be a significant risk factor, diagnosis and treatment of bipolarity has become a very important issue. Since there is a lack of specific diagnostic criteria for especially preadolescent samples and evaluations are made mostly symptomatically, suspicions about false true diagnosis and increased prevalence rates have emerged. This situation leads to controversial data about the prevalence rates of bipolar disorder in children and adolescents. The aim of this article is to review the prevalence of childhood and adolescent bipolar disorder in community, inpatient and outpatient based samples in literature.

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“…3 Considering bipolar spectrum disorders, from 4 to 18% of children and adolescents referred to psychiatric evaluations satisfy the criteria for those disorders. 4 Attention-deficit/hyperactivity disorder (ADHD) is present in about 5% of children and adolescents across different cultures. 5 High rates of comorbidity between ADHD and BD are observed in childhood (over 60%), especially in clinical samples.…”

Section: Introductionmentioning

confidence: 99%

Does comorbid bipolar disorder increase neuropsychological impairment in children and adolescents with ADHD?

Narvaez

Zeni

Coelho

et al. 2014

Rev. Bras. Psiquiatr.

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Objective: To assess differences in executive functioning between children and adolescents with attention-deficit/hyperactivity disorder (ADHD) comorbid or not with bipolar disorder (BD), and to study the neuropsychological profile of subjects with the comorbidity in a clinical sample from a developing country. Method: Case-control study comparing 23 participants with BD + ADHD and 85 ADHD-only subjects aged 6 to 17 years old. Both groups were drug-free. Executive function domains were assessed with the Stroop Test, the Wisconsin Card Sorting Test, and the Continuous Performance Test II. Results: The group with juvenile BD + ADHD showed a significantly worse performance on the Stroop task, including time in color (p = 0.002), time in color-word (p , 0.001), interference, number or errors in color and color-word (p = 0.001), and number of errors in word cards (p = 0.028). No between-group differences were found in other tests. Conclusions: Our findings suggest that ADHD-only and ADHD + BD do not show differences in inhibitory control and set-shifting domains. However, children and adolescents with BD and comorbid ADHD show greater impairment in processing speed and interference control. This suggests a potentially higher impairment in the dorsolateral prefrontal cortex and may be a potential neuropsychological signature of juvenile BD comorbid with ADHD.

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Bipolar disorder in children and adolescents: international perspective on epidemiology and phenomenology

Cited by 113 publications

References 51 publications

Mood disorders in childhood and adolescence

Mood disorders in childhood and adolescence

Epidemiology in Pediatric Bipolar Disorder

Does comorbid bipolar disorder increase neuropsychological impairment in children and adolescents with ADHD?

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