Bipolar Disorder Associated with Turnerʼs Syndrome

Panzer, Michael J.; Tandon, Rajiv

doi:10.1097/00005053-199111000-00010

Cited by 8 publications

(4 citation statements)

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“…In addition, a case report of a 36-year-old woman, with a 15-year psychiatric history and a TS diagnosis at age 14 years, revealed a possible association between bipolar disorder (BD) and TS. Only one other case with both of these disorders was described in the literature [20]. Several studies have suggested X chromosome linkage for BD, and this report may be further evidence that BD could be linked to the X chromosome in a subset of patients [20].…”

Section: Turner Syndromesupporting

confidence: 57%

“…Only one other case with both of these disorders was described in the literature [20]. Several studies have suggested X chromosome linkage for BD, and this report may be further evidence that BD could be linked to the X chromosome in a subset of patients [20].…”

Section: Turner Syndromesupporting

confidence: 57%

“…In addition to nonspecific and sub-threshold psychiatric symptoms, girls with TS are at higher risk for developing axis I disorders, such as attention-deficit hyperactivity disorder (ADHD) compared with the general population [20]. According to Firth et al, weaknesses in core cognitive skills, including difficulties with distraction, planning, and short-term and working memory contribute to patterns of behavior present in ADHD.…”

Section: Turner Syndromementioning

confidence: 99%

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Psychiatric Comorbidities in Common Genetic Disorders with Physical Disability

Maalouf¹,

Hatoum²,

Atwi³

et al. 2010

Pediatric Health

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The burden of genetic disorders associated with physical disabilities and psychiatric disorders is connected to increasing healthcare expenses and demands on the patients and their caregivers. Psychiatric comorbidities such as anxiety and mood disorders affect a large number of children and adolescents with genetic disorders, leading to poor quality of life and impaired psychological adjustment. Research on this population is scarce compared with studies on the comorbidity of psychiatric problems with physical illnesses (e.g., endocrine disorders and neurological problems). The aim of this review is to focus on the most prevalent genetic disorders that cause physical disability and are most commonly associated with psychiatric disorders in children and adolescents. These include Duchenne muscular dystrophy, neurofibromatosis, myotonic dystrophy, hemophilia, Turner syndrome, Klinefelter’s syndrome, tuberous sclerosis complex, fragile X syndrome and velo-cardio-facial syndrome.

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Section: Turner Syndromesupporting

confidence: 57%

Section: Turner Syndromesupporting

confidence: 57%

Section: Turner Syndromementioning

confidence: 99%

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Psychiatric Comorbidities in Common Genetic Disorders with Physical Disability

Maalouf¹,

Hatoum²,

Atwi³

et al. 2010

Pediatric Health

View full text Add to dashboard Cite

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“…Regarding symptom severity, two of these studies (Money & Mittenthal, 1970;Nielsen et al, 1977) reported an average severity of depressive illness, while the remaining three were not able to comment on severity (Bender et al, 1995;Nielsen & Stradiot, 1987;Sabbath et al, 1961). The remaining nine articles (26% of the surveyed literature) are case reports or case series that relied only on expert opinion to make the determination of depression (Quality of Data Level 4), thus by design they do not have a control group or present data that are comparable to other populations (Christodorescu, Collino, Zellingher, & Tăutu, 1970;Dickens, 1970;Fishbain & Vilasuso, 1981;Larocca, 1985;Nielsen, 1970;Nielsen & Thomsen, 1968;Panzer & Tandon, 1991;Pitts & Guze, 1963;Shea & Wolfman, 2017). Table 2 summarizes the studies discussed above, categorized by method of depression evaluation and presence/ absence of control group.…”

Section: Resultsmentioning

confidence: 99%

Depression in Turner Syndrome: A Systematic Review

et al. 2019

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Turner syndrome (TS) is a genetic condition characterized by partial or complete monosomy X. Alterations in hormonal function, height, and peer relationships, among other features and correlates of TS, appear to be risks for depressive illness. In order to summarize what is known about depression in Turner syndrome, with the aim of determining if individuals with TS are at increased risk for depression, a literature search and analysis was conducted. In total, 69 studies were identified and 35 met criteria of being peer-reviewed English language articles that collected original data on the experience of depression in individuals with TS. Most studies used patient or parent questionnaires to evaluate depressive symptoms. These studies, a majority of which examined adults and half that examined adolescents, found that individuals with TS experienced more frequent and severe depressive symptoms than individuals without TS diagnoses. Articles studying children with TS did not demonstrate a difference in their depressive experience compared to individuals without TS. Three articles used clinician administered scales, such as the Structured Clinical Interview for DSM-IV; all diagnosed depression in those with TS at higher rates than others. Five studies relied on expert opinion to evaluate depression. The remaining eight articles were case reports or case series that relied on expert opinion. From these data, we conclude that adolescents and adults with TS are at risk for depression and adulthood appears to be the period of highest risk. Studies in the last 12 years show consistently more severe depressive symptoms in individuals with TS than in previous years. Implications, risk factors, and recommendations for future research are discussed.

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Bipolar Disorder Associated With Klinefelter's Syndrome and Other Chromosomal Abnormalities

Everman

Stoudemire

1994

Psychosomatics

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Bipolar Disorder Associated with Turnerʼs Syndrome

Cited by 8 publications

References 0 publications

Psychiatric Comorbidities in Common Genetic Disorders with Physical Disability

Psychiatric Comorbidities in Common Genetic Disorders with Physical Disability

Depression in Turner Syndrome: A Systematic Review

Bipolar Disorder Associated With Klinefelter's Syndrome and Other Chromosomal Abnormalities

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