Biosynthesis of CaO nanoparticles using Trigona sp. Honey: Physicochemical characterization, antifungal activity, and cytotoxicity properties

Maringgal, Bernard; Hashim, Norhashila; Tawakkal, Intan Syafinaz Mohamed Amin; Hamzah, Muhammad Hazwan; Mohamed, Mahmud Tengku Muda

doi:10.1016/j.jmrt.2020.08.054

Cited by 28 publications

(12 citation statements)

References 58 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…They are effective against microorganisms, such as Streptococcus aureus, Bacillus cereus, Escherichia coli, and Pseudomonas aeruginosa [7]. Moreover, the antifungal activity of calcium oxide nanoparticles against several fungal strains, such as Colletotrichum brevisporum and Colletotrichum gloeosporioides, has also been reported [12]. The synthesis and production of calcium oxide nanoparticles have also been increased because of the increasing application.…”

Section: Introductionmentioning

confidence: 99%

Cellular Investigations on Mechanistic Biocompatibility of Green Synthesized Calcium Oxide Nanoparticles with Danio rerio

Eram

Kumari

Panda

et al. 2021

JNT

View full text Add to dashboard Cite

The utility of calcium oxide nanoparticles in the biomedical and physical fields has instigated their biocompatible synthesis and production. Moreover, it is important to investigate their biocompatibility at the molecular level for biomedical and ecotoxicological concern. This study explores the green synthesis of calcium oxide nanoparticles (CaONP) using Crescentia cujete leaf extract. The synthesized CaONP were found to have a size of 62 ± 06 nm and a hydrodynamic diameter of 246 ± 12 nm, as determined by FE-SEM and dynamic light scattering (DLS). CaONP was stable in fish medium with a zeta potential of −23 ± 11 mV. The biocompatibility of the CaONP was investigated with adult zebrafish bearing an LC50 of 86.32 µg/mL. Cellular and molecular investigation revealed the mechanism of biocompatibility as a consequence of elicited reactive oxygen species leading to apoptosis, due to accumulation and internalization of CaONP in exposed zebrafish. The study provided detailed information about the mechanistic biocompatibility and a defined horizon of green synthesis of CaONP for biomedical and ecological purposes.

show abstract

Section: Introductionmentioning

confidence: 99%

Cellular Investigations on Mechanistic Biocompatibility of Green Synthesized Calcium Oxide Nanoparticles with Danio rerio

Eram

Kumari

Panda

et al. 2021

JNT

View full text Add to dashboard Cite

show abstract

“…The band around 1648 cm −1 indicates the stretching of C=O in the carboxylic functional group, whereas the band at 1051 cm −1 and 1259 cm −1 corresponds to the stretching vibration of C–OH and C–O in the honey [ 39 ]. Next, the peak which appeared at 924 cm −1 was attributed to the stretching modes of carbohydrates in the honey, such as C-O and C-C [ 40 ]. However, observation of the formulations A1, A2, and A3 indicated a peak around band 1740 cm −1 , which was attributed to the stretching vibration of C=O in the oleic acid [ 41 ].…”

Section: Resultsmentioning

confidence: 99%

Optimisation of Stingless Bee Honey Nanoemulsions Using Response Surface Methodology

Rozman

Hashim

Maringgal³

et al. 2021

Foods

Self Cite

View full text Add to dashboard Cite

Nanoemulsions (NEs) have been used in a wide range of products, such as those produced by the food, cosmetics, and pharmaceutical industries, due to their stability and long shelf life. In the present study, stingless bee honey (SBH) NEs were formulated using SBH, oleic acid, tween 80, glycerol, and double-distilled water. SBH NEs were prepared using a high-pressure homogeniser and were characterised by observing their stability and droplet size. Fourier Transform-Infrared (FTIR) analysis was used to observe the functional groups of the SBH NEs after being subjected to high-pressure homogenisation. Transmission Electron Microscopy (TEM) images were then used to confirm the particle size of the SBH NEs and to investigate their morphology. The effects of the independent variables (percentage of oleic acid, storage time, and storage temperature) on the response variables (particle size and polydispersity index) were investigated using the response surface methodology, along with a three-level factorial design. The results showed that the models developed via the response surface methodology were reliable, with a coefficient of determination (R2) of more than 0.90. The experimental validation indicated an error of less than 10% in the actual results compared to the predicted results. The FTIR analysis showed that SBH NEs have the same functional group as SBH. Observation through TEM indicated that the SBH NEs had a similar particle size, which was between 10 and 100 nm. Thus, this study shows that SBH NEs can be developed using a high-pressure homogeniser, which indicates a new direction for SBH by-products.

show abstract

“…The KH Nps were generated as described by Maringgal et al [ 31 ] through deposition as well as precipitation of calcium carbonate (CaCO 3 ) in KH via biosynthesis.…”

Section: Methodsmentioning

confidence: 99%

“…Nano-coating of KH Nps at 15% concentration ( w/v ) containing 1% glycerol and Tween 20 were prepared as described by Maringgal et al [ 31 ]. The papayas were dipped into the KH Nps concentrations for 1 min and then air-dried for a duration of 2 h. The samples were packed in commercial corrugated boxes in a single layer and stored at 12 ± 1 °C with 85–90% relative humidity for 21 days.…”

Section: Methodsmentioning

confidence: 99%

“…It was found that nano-coating successfully maintained the quality of papayas, extended the shelf life of papaya up to 14 days, controlled the development of anthracnose disease, and reduced the rate of respiration of the fruit during storage. According to Maringgal et al [ 31 ], this could be due to the reduced Nps size that leads to superior Nps penetration, absorption, as well as migration into fruits, thus promoting an effective coating system.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effect of Kelulut Honey Nanoparticles Coating on the Changes of Respiration Rate, Ascorbic Acid, and Total Phenolic Content of Papaya (Carica papaya L.) during Cold Storage

Maringgal

Hashim

Tawakkal

et al. 2021

Foods

Self Cite

View full text Add to dashboard Cite

This study evaluated the respiration rate of coated and uncoated (control) papayas (Carica papaya L.) with 15% of Kelulut honey (KH) nanoparticles (Nps) coating solution during cold storage at 12 ± 1 °C for 21 days. The respiration rate of the papayas significantly changed during storage, with an increase in CO2 and a decrease in O2 and C2H4, while the ascorbic acid and total phenolic content was maintained. The changes in respiration rate were rather slower for coated papayas when compared to control ones. A kinetic model was established from the experimental data to describe the changes of O2, CO2, and C2H4 production in papayas throughout the storage period. All O2, CO2, and C2H4 were experimentally retrieved from a closed system method and then represented by the Peleg model. The outcomes indicated the Peleg constant K1 and K2, which were gained from linear regression analysis and coefficients of determination (R2), seemed to fit well with the experimental data, whereby the R2 values exceeded 0.85 for both coated and control papayas. The model confirmed both the capability and predictability aspects of the respiration rate displayed by papayas coated with KH Nps throughout the cold storage period. This is supported by the differences in the stomatal aperture of coated and control papaya shown by microstructural images.

show abstract

Biosynthesis of CaO nanoparticles using Trigona sp. Honey: Physicochemical characterization, antifungal activity, and cytotoxicity properties

Cited by 28 publications

References 58 publications

Cellular Investigations on Mechanistic Biocompatibility of Green Synthesized Calcium Oxide Nanoparticles with Danio rerio

Cellular Investigations on Mechanistic Biocompatibility of Green Synthesized Calcium Oxide Nanoparticles with Danio rerio

Optimisation of Stingless Bee Honey Nanoemulsions Using Response Surface Methodology

Effect of Kelulut Honey Nanoparticles Coating on the Changes of Respiration Rate, Ascorbic Acid, and Total Phenolic Content of Papaya (Carica papaya L.) during Cold Storage

Contact Info

Product

Resources

About