Biosensor-Based Technologies for the Detection of Pathogens and Toxins

Moran, Kara; Fitzgerald, Jenny; McPartlin, Daniel A; Loftus, Jonathan H; O’Kennedy, Richard

doi:10.1016/bs.coac.2016.04.002

Cited by 16 publications

(10 citation statements)

References 142 publications

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“…One of the key challenges in developing a fully automatic toxin detector is toxin extraction from complex food samples [ 69 ]. Future systems are expected to extract, process, and measure toxins to determine their harmful levels from food and water samples automatically [ 69 , 70 ]. Advanced separation techniques have been coupled with SERS in identifying, discriminating, and quantifying chemical toxins in food matrices [ 71 ].…”

Section: Biosensing In Food Safety and Securitymentioning

confidence: 99%

Biosensors for Sustainable Food Engineering: Challenges and Perspectives

et al. 2018

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Current food production faces tremendous challenges from growing human population, maintaining clean resources and food qualities, and protecting climate and environment. Food sustainability is mostly a cooperative effort resulting in technology development supported by both governments and enterprises. Multiple attempts have been promoted in tackling challenges and enhancing drivers in food production. Biosensors and biosensing technologies with their applications, are being widely applied to tackling top challenges in food production and its sustainability. Consequently, a growing demand in biosensing technologies exists in food sustainability. Microfluidics represents a technological system integrating multiple technologies. Nanomaterials, with its technology in biosensing, is thought to be the most promising tool in dealing with health, energy, and environmental issues closely related to world populations. The demand of point of care (POC) technologies in this area focus on rapid, simple, accurate, portable, and low-cost analytical instruments. This review provides current viewpoints from the literature on biosensing in food production, food processing, safety and security, food packaging and supply chain, food waste processing, food quality assurance, and food engineering. The current understanding of progress, solution, and future challenges, as well as the commercialization of biosensors are summarized.

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Section: Biosensing In Food Safety and Securitymentioning

confidence: 99%

Biosensors for Sustainable Food Engineering: Challenges and Perspectives

et al. 2018

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“…We recognize the many other excellent publications that precede this one and, in fact, were supported strongly by them in many cases. Particularly, the reviews by Gooding [ 56 ], Mirski et al [ 57 ], Moran et al [ 58 ], Dorner et al [ 59 ], and Walper et al [ 32 ] provide an overview of various technologies used for detection of biothreat agents in environmental and food samples as well as for clinical diagnostics. In the following sections, different immunoassay-based multiplex techniques for on-site detection of security sensitive toxins are presented.…”

Section: Portable Immunoassay Techniques With Multiplexing Capabilmentioning

confidence: 99%

Multiplex Immunoassay Techniques for On-Site Detection of Security Sensitive Toxins

Pöhlmann

Elßner

2020

Toxins

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Biological toxins are a heterogeneous group of high molecular as well as low molecular weight toxins produced by living organisms. Due to their physical and logistical properties, biological toxins are very attractive to terrorists for use in acts of bioterrorism. Therefore, among the group of biological toxins, several are categorized as security relevant, e.g., botulinum neurotoxins, staphylococcal enterotoxins, abrin, ricin or saxitoxin. Additionally, several security sensitive toxins also play a major role in natural food poisoning outbreaks. For a prompt response to a potential bioterrorist attack using biological toxins, first responders need reliable, easy-to-use and highly sensitive methodologies for on-site detection of the causative agent. Therefore, the aim of this review is to present on-site immunoassay platforms for multiplex detection of biological toxins. Furthermore, we introduce several commercially available detection technologies specialized for mobile or on-site identification of security sensitive toxins.

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“…The theory of biosensors has been discussed extensively in other review articles [23,24]. Additionally, biosensors designed to specifically measure marine toxins have been previously reviewed [25,26]. Therefore, the focus of this review will be on recently 1.E+04…”

Section: Habs Present a Significant Monitoring Challengementioning

confidence: 99%

Biosensors for the monitoring of harmful algal blooms

McPartlin

Loftus

Crawley

et al. 2017

Current Opinion in Biotechnology

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Harmful algal blooms (HABs) are a major global concern due to their propensity to cause environmental damage, healthcare issues and economic losses. In particular, the presence of toxic phytoplankton is a cause for concern. Current HAB monitoring programs often involve laborious laboratory-based analysis at a high cost and with long turnaround times. The latter also hampers the potential to develop accurate and reliable models that can predict HAB occurrence. However, a promising solution for this issue may be in the form of remotely deployed biosensors, which can rapidly and continuously measure algal and toxin levels at the point-of-need (PON), at a low cost. This review summarises the issues HABs present, how they are difficult to monitor and recently developed biosensors that may improve HAB-monitoring challenges.

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Biosensor-Based Technologies for the Detection of Pathogens and Toxins

Cited by 16 publications

References 142 publications

Biosensors for Sustainable Food Engineering: Challenges and Perspectives

Biosensors for Sustainable Food Engineering: Challenges and Perspectives

Multiplex Immunoassay Techniques for On-Site Detection of Security Sensitive Toxins

Biosensors for the monitoring of harmful algal blooms

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