Biopolymer-coated liposomes by electrostatic adsorption of chitosan (chitosomes) as novel delivery systems for carotenoids

Insights on the antifungal activity of amphiphilic derivatives of diethylaminoethyl chitosan against Aspergillus flavus

“…Hence, the addition of TRITON-X100 resulted only in minor increases in fluorescence, corroborating the interpretation given to DLS and zeta potential measurements ( Fig. 3) and supporting the proposal of formation of stabilized liposomes (Quemeneur, Rinaudo, Maret, & Pépin-Donat, 2010;Tan et al, 2015Tan et al, , 2016. However, the formation of pores cannot be disregarded by the present results, being dependent on the type of liposome (Mertins & Dimova, 2013) and the concentration used in the experiment (Tan et al, 2015).…”

“…Moreover, zeta potential of the mixtures of DEAE-CH 130 with PC vesicles reached higher zeta values (+20 mV), indicating a more efficient adsorption on the liposome surface. Accordingly, the aggregation process decreased due to electrostatic repulsion between the charged liposomes as reported in earlier studies (Quemeneur, Rinaudo, & Pépin-Donat, 2008;Tan, Feng, Zhang, Xia, & Xia, 2016). The more efficient adsorption of DEAE-CH 130 compared to CH can be explained taking into account its more hydrophobic character inferred from the fluorescence studies with pyrene.…”

Calcium alginate microspheres containing metformin hydrochloride niosomes and chitosomes aimed for oral therapy of type 2 diabetes mellitus

“…This result was attributed to a competition between the lidocaine and CS molecules (both ionized at the pH 5.0 of experimental conditions), for interaction with phosphatidylcholine, which hindered drug retention into the vesicles (González-Rodríguez et al, 2007). On the contrary, other authors found a positive effect of CS coating amount on liposome encapsulating ability of carotenoids, and ascribed this result to a reduced drug leakage from the vesicles, during the preparation procedure, owing to the polymer coating (Tan et al, 2016). …”

Potential of Stratum Corneum Lipid Liposomes for Screening of Chemical Skin Penetration Enhancers

“…22) The blank SCLLs and 2×10 −5 M DPH solution in phosphate buffered saline (PBS) (25 : 75 µL) was firstly mixed in a 96-well plate and then subjected to shaking in an orbital shaker (IKA ® MS1 Minishaker, Sigma-Aldrich, Willmington, NC, U.S.A.) at 500 rpm for 30 min in the absence of light. Next, different concentrations of CPEs in 0.1 M borate buffer (100 µL) were added and shaken in the same conditions.…”