Biomonitoring of pollen grains of a river bank suburban city, Konnagar, Calcutta, India, and its link  and impact on local people

Ghosal, Kavita; Pandey, Naren; Bhattacharya, Swati Gupta

doi:10.5604/12321966.1152072

Cited by 9 publications

(7 citation statements)

References 17 publications

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“…Another similar study conducted in Calcutta, 2008, reported a number of pollen types in the air [17]. The most predominant pollen found from the Burkard 7-day volumetric sampler was Trema orientalis (19%), followed by Poaceae A recent aeropalynological work using a Burkard 7-day volumetric sampler in a suburban city of Konnagar, near to Calcutta, West Bengal, marked the prevalence of 36 types of pollen in the air [18].…”

Section: In Eastern Regionmentioning

confidence: 86%

Current glimpse of airborne allergenic pollen in Indian subcontinent

Ghosal

Gupta‐Bhattacharya

2015

Acta Agrobot

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Respiratory allergic diseases such as bronchial asthma, rhinitis, urticaria, atopic dermatitis have been steadily increasing all over the world, including India. Owing to its alarming trend, several aerobiological surveys have been undertaken in different parts of India to delineate the variety of pollen and spore load. In this review, we have reported the current state of aerobiological knowladge in India with particular reference to allergenic airborn pollen occurence in 2001–2015. Pollen have been found to contribute a significant proportion in the air and caused allergy symptoms in the local inhabitants. Aerobiological records, a questionnaire survey and hospitalization records have been employed for the analysis. Holoptelea integrifolia, Amaranthus spinosus in northern region, Sorghum vulgare, Pennisetum, Gynandropsis gynandra, Parthenium hysterophorus, Dolichandrone platycalyx in southern regions, and Parthenium hysterophorus from the western region; Cynodon dactylon, Cenchrus ciliaris in the central area; Acacia auriculiformis, Cleome gynandra, Catharanthus roseus, Phoenix sylvestris, Areca catechu, and Lantana camara in the eastern regions as potential aeroallergens in India. The statistical approach confirmed the correlation between hospitalization rate associated with allergy-related health troubles and the prevalent allergenic pollen in the air. The Poaceae group has been found to be dominant throughout India. Immuno-biochemical studies identified various protein with allergenic potential found in the pollen recorded. Epitope identification and homology of the major allergenic protein Cat r1 of Catharanthus sp and Par j 1 of Parietaria judaica have been found. Identification of allergenic pollen grains and the modern approach concerning cross-reactivity and epitope revelation of dominant airborne pollen have important clinical implications for the prevention, diagnosis and treatments of allergic diseases in India.

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Section: In Eastern Regionmentioning

confidence: 86%

Current glimpse of airborne allergenic pollen in Indian subcontinent

Ghosal

Gupta‐Bhattacharya

2015

Acta Agrobot

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“…Pollen calendars from different regions in India. (A) Northern (Chandigarh), 40 (B) Eastern (Kolkata; West Bengal), 42 (C) Western (Jaipur, Rajasthan) 57 …”

Section: Prevalence Of Allergies Against Different Sources Of Aero‐al...mentioning

confidence: 99%

A review on aero‐allergen induced allergy in India

Laha

Moitra²,

Podder

2023

Clin Experimental Allergy

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Allergic diseases such as bronchial asthma, rhinitis and eczema are an important public health issue globally in 21st century. Their prevalence and impact in India is high, in terms of total numbers of people affected. Due to diverse climate and lifestyle, the Indian population is exposed to a rich and varied range of aerobiological particles. In the last two decades in India, 83 pollens, 34 fungi, six dust mite and 19 insect species were reported as allergenic, often contributing to heavy allergenic exposure in indoor and outdoor environments. There are currently few practitioners who offer allergy diagnosis and treatment in India, but there is active basic and molecular research aiming to improve the health of allergic patients. This review explores the field of aero-allergy in India during the last two decades, with special emphasis on prevalence across various centres and relevant scientific advances such as genetic associations and new therapeutics. This review will be helpful for clinicians to select aero-allergens for sensitisation testing in patients suffering from symptoms in different regions of India, and to support patients undertaking prophylaxis of allergic symptoms in India according to local environmental conditions. This study also helps to define patient selection for allergy testing and the role of test results in guiding allergic disease management in the Indian context. Finally, we summarize genetic findings relevant to aero-allergy in India and discuss the development of novel therapeutics for investigation and management of aero-allergy in India.

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“…The papaya fruits are consumed either in ripe form simply as fruits or cooked as vegetables at the pre-ripening stage. It is a wind-pollinated plant, and the pollen grains are the primary constituents of ambient bioaerosol ( Ghosal et al, 2015 ). These pollen grains are rich sources of aeroallergens, which can elicit IgE-mediated sensitization of respiratory mucosa leading to symptoms like asthma, allergic rhinitis, and hay fever ( Blanco et al, 1998 ).…”

Section: Introductionmentioning

confidence: 99%

Cari p 1, a Novel Polygalacturonase Allergen From Papaya Acting as Respiratory and Food Sensitizer

et al. 2018

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Papaya has been reported to elicit IgE-mediated hypersensitivity via pollen inhalation and fruit consumption. Certain papaya sensitive patients with food allergy were found to experience recurrent respiratory distresses even after quitting the consumption of fruits. This observation prompted us to investigate the allergens commonly present in fruits and pollen grains of papaya. A discovery approach consisting of immunoproteomic detection followed by molecular characterization led to the identification of a novel papaya allergen designated as Cari p 1. This allergen was detected as a 56 kDa IgE-reactive protein from pollen as well as fruit proteome through serological analysis. The protein was identified as an endopolygalacturonase by tandem mass spectrometry. Full length Cari p 1 cDNA was isolated from papaya pollen, cloned in expression vector, and purified as recombinant allergen. The recombinant protein was monomeric and displayed pectinolytic activity. Recombinant Cari p 1 reacted with IgE-antibodies of all the papaya sensitized patient sera. In addition to IgE-reactivity, rCari p 1 displayed allergenic activity by stimulating histamine release from IgE-sensitized granulocytes. CD-spectroscopy of rCari p 1 revealed the presence of predominantly β-sheet characters. The melting curve of the allergen showed partial refolding from a fully denatured state indicating the possible presence of conformational IgE-epitopes characteristic of inhalant allergens in addition to the linear IgE-epitopes of food allergens. The expression of this allergen in papaya fruits was detected by immunoblot with anti-Cari p 1 rabbit IgG and reconfirmed by PCR. In an in vivo mouse model, rCari p 1 exhibited a comparable level of inflammatory responses in the lung and duodenum tissues explaining the dual role of Cari p 1 allergen in respiratory sensitization via pollen inhalation and sensitization of gut mucosa via fruit consumption. Purified rCari p 1 can be used a marker allergen for component-resolved molecular diagnosis. Further immunological studies on Cari p 1 are warranted to design immunotherapeutic vaccine for the clinical management of papaya allergy.

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Biomonitoring of pollen grains of a river bank suburban city, Konnagar, Calcutta, India, and its link and impact on local people

Cited by 9 publications

References 17 publications

Current glimpse of airborne allergenic pollen in Indian subcontinent

Current glimpse of airborne allergenic pollen in Indian subcontinent

A review on aero‐allergen induced allergy in India

Cari p 1, a Novel Polygalacturonase Allergen From Papaya Acting as Respiratory and Food Sensitizer

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