Biomonitoring of bisphenol A in hair of Greek population

Tzatzarakis, Manolis; Vakonaki, Elena; Kavvalakis, Matthaios; Barmpas, M.; Kokkinakis, Manolis; Xenos, K.; Tsatsakis, Aristidis

doi:10.1016/j.chemosphere.2014.10.044

Cited by 49 publications

(20 citation statements)

References 23 publications

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“…BPA has been detected in different human biological matrices such as urine, blood, colostrum, breast milk, and other tissues in recent years (Geens et al, 2012b;Li et al, 2013;Migeot et al, 2013;Mendonca et al, 2014;Zimmers et al, 2014;Arbuckle et al, 2015;Nahar et al, 2015). BPA was also detected in the 41.2% of the hair samples collected from the Greek urban population versus 14.8% of the positive samples from the rural population (Tzatzarakis et al, 2015). However, this is the only study that has been done and published so far concerning the BPA measurement in human hair in order to estimate a chronic and long-term exposure to it.…”

Section: Introductionmentioning

confidence: 87%

Estimation of in vivo and in vitro exposure to bisphenol A as food contaminant

Milić

Četojević-Simin

Milanović

et al. 2015

Food and Chemical Toxicology

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Section: Introductionmentioning

confidence: 87%

Estimation of in vivo and in vitro exposure to bisphenol A as food contaminant

Milić

Četojević-Simin

Milanović

et al. 2015

Food and Chemical Toxicology

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“…The extraction method that was followed is described in previous study (Tzatzarakis et al, ). In brief, hair samples (100 mg) were washed twice with water and methanol for the removal of external contaminants and then dried at 50°C.…”

Section: Methodsmentioning

confidence: 99%

Biomonitoring of bisphenol A, triclosan and perfluorooctanoic acid in hair samples of children and adults

Karzi

Tzatzarakis

Vakonaki

et al. 2018

J of Applied Toxicology

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Bisphenol A (BPA), triclosan (TCS) and perfluorooctanoic acid (PFOA) are endocrine disruptors linked with negative health effects such as developmental, reproductive and cardiovascular toxicity. The aim of this study was to determine simultaneously the concentration of BPA, TCS and PFOA in hair from children and adults and examine possible associations between biomonitoring data and age, gender, dietary habits and body mass index. Methanolic extraction was applied and the compounds were determined by liquid chromatography-mass spectrometry. Low levels of exposure to PFOA were detected for children and adults at concentrations below limit of quantification. The mean concentration of BPA in children and adults was 20.6 and 16.6 pg mg , while for TCS 275.2 and 687.0 pg mg , respectively. Children were highly exposed to BPA relative to adults (P = .011) although adults had greater exposure to TCS (P = .003). Hair from girls had a greater burden of BPA (P = .06) compared to boys. Moreover, higher TCS levels were depicted for females in both examined groups (children P = .200 and adults P = .213) compared to males, but no statistical differences were observed. Significant differences were also observed between age groups (P = .0007) for TCS. No correlations were found between BPA or TCS levels and body mass index or dietary habits for both children and adults. Children have a greater exposure to BPA compared to adults, whereas exposure of adults to TCS seems to be higher than that in children and elderly people. Exposure to BPA occurs mainly via ingestion whereas exposure to TCS mainly via dermal absorption.

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“…Quantification of BPA in sweat via solid phase extraction (SPE) followed by analysis with HPLC has shown that BPA could be recorded in 16 of the 20 samples. Moreover, the team was careful in their sample collection methodology for directly transferring sweat from skin to the glass containers using stainless steel spatulae [ 15 ]. In a similar study conducted in 2015 the amount of BPA excreted in sweat of 50 subjects was attempted but used polyurethane sweat patches to later extract BPA by placing the patches in polypropylene plastic tubes.…”

Section: Introductionmentioning

confidence: 99%