Biomonitoring for arsenic, toxic and essential metals in single hair strands by laser ablation inductively coupled plasma mass spectrometry

Kumtabtim, Usarat; Matusch, Andreas; Dani, Sergio U.; Siripinyanond, Atitaya; Becker, J. Sabine

doi:10.1016/j.ijms.2011.03.007

Cited by 25 publications

(13 citation statements)

References 18 publications

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“…The RSD of each point was less than 15%. The limit of detection (LOD) was calculated by the ablation of 10 washed native unexposed hair strands 15 .…”

Section: Methodsmentioning

confidence: 99%

Determination of arsenic and lead in single hair strands by laser ablation inductively coupled plasma mass spectrometry

Luo

et al. 2017

Sci Rep

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The purpose of this study was to develop matrix-matched hair standards and a LA-ICP-MS technique for determination of the As and Pb in a single human hair using single spot scan mode. These results could subsequently be used to infer when the element entered the body. This study was conducted in two parts. First, a method was developed and validated for the elemental analysis of hair by LA-ICP-MS. A calibration strategy in LA-ICP-MS was developed using prepared matrix-matched laboratory hair standards doped with analytes of interest at a defined concentration. The use of hair strand standards enables calibration curves to be obtained by plotting the analyte ion (M+) intensity normalized to34S+(the ratio M+/34S+) as a function of the concentration determined by ICP-MS of the acidic digests. The linear correlation coefficients (R2) of the calibration curves for the analytes As and Pb were typically between 0.9970 and 0.9998, respectively. Second, an actual hair was measured using the developed method. The spatial distribution of As along the hair was observed in a hair sample from a leukaemia patient treated with arsenic trioxide (As2O3). The actual and estimated times over which the drug entered the body were compared and discussed.

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“…The RSD of each point was less than 15%. The limit of detection (LOD) was calculated by the ablation of 10 washed native unexposed hair strands 15 .…”

Section: Methodsmentioning

confidence: 99%

Determination of arsenic and lead in single hair strands by laser ablation inductively coupled plasma mass spectrometry

Luo

et al. 2017

Sci Rep

View full text Add to dashboard Cite

show abstract

“…A more simplistic method for ICP-MS was further developed to cut down on time and resources by coupling high-performance liquid chromatography with ICP-MS [102]. Another method, laser ablation-ICP-MS, gives the spatial distribution of trace elements in a single strand, thereby giving a timeline for exposure with a high degree of accuracy from a minute specimen [103–105].…”

Section: Hair Metabolomicsmentioning

confidence: 99%

Metabolomics of Pregnancy Complications: Emerging Application of Maternal Hair

Delplancke

Han

et al. 2018

BioMed Research International

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In recent years, the study of metabolomics has begun to receive increasing international attention, especially as it pertains to medical research. This is due in part to the potential for discovery of new biomarkers in the metabolome and to a new understanding of the “exposome”, which refers to the endogenous and exogenous compounds that reflect external exposures. Consequently, metabolomics research into pregnancy-related issues has increased. Biomarkers discovered through metabolomics may shed some light on the etiology of certain pregnancy-related complications and their adverse effects on future maternal health and infant development and improve current clinical management. The discoveries and methods used in these studies will be compiled and summarized within the following paper. A further focus of this paper is the use of hair as a biological sample, which is gaining increasing attention across diverse fields due to its noninvasive sampling method and the metabolome stability. Its significance in exposome studies will be considered in this review, as well as the potential to associate exposures with adverse pregnancy outcomes. Currently, hair has been used in only two metabolomics studies relating to fetal growth restriction (FGR) and gestational diabetes mellitus (GDM).

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“…Calibration strategies for analysis of single hair strands by LA-ICP-MS were investigated by Kumtabtim et al 55 Using either powdered hair CRM or human hair doped with known amounts of analytes, mounted on sticky tape, very similar calibration curves were produced. The 34 S + ion was used as the internal standard.…”

Section: Digestion Extraction and Preconcentrationmentioning

confidence: 99%

“…Richardson et al 48 examined the use of collision cell technology to overcome interferences from FeH on the quantitative determination of Mn in plasma and whole blood. It was established that the interference from FeH on 55 Mn was not eliminated by this approach. However, the interference was successfully overcome by modifying the geometry of the skimmer cones of the ICPmass spectrometer.…”

Section: View Article Onlinementioning

confidence: 99%

Atomic spectrometry update. Clinical and biological materials, foods and beverages

Taylor

Branch

Day

et al. 2010

J. Anal. At. Spectrom.

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Biomonitoring for arsenic, toxic and essential metals in single hair strands by laser ablation inductively coupled plasma mass spectrometry

Cited by 25 publications

References 18 publications

Determination of arsenic and lead in single hair strands by laser ablation inductively coupled plasma mass spectrometry

Determination of arsenic and lead in single hair strands by laser ablation inductively coupled plasma mass spectrometry

Metabolomics of Pregnancy Complications: Emerging Application of Maternal Hair

Atomic spectrometry update. Clinical and biological materials, foods and beverages

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