Biomedical investigation of CNT based coatings

Li, Xiaoming; Liu, Xi; Huang, Jin; Fan, Yubo; Cui, Fuzhai

doi:10.1016/j.surfcoat.2011.02.063

Cited by 99 publications

(62 citation statements)

References 86 publications

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“…However, HA has low toughness and flexural strength in the application of load-bearing skeleton [7]. Carbon nanotubes (CNTs) can simulate the dimensions of proteins that comprise native tissue and have the higher reactivity for interactions involved in the cell attachment mechanism, and it can also increase the fracture toughness of brittle HA bioceramics matrix [8][9][10]. Therefore, the incorporation of CNTs as a secondary constituent material into bioactive coating can stimulate the attachment and proliferation of osteobalst cell by providing a nanostructured surface of the pore walls [11].…”

Section: Introductionmentioning

confidence: 99%

Effect of the addition CNTs on performance of CaP/chitosan/coating deposited on magnesium alloy by electrophoretic deposition

Zhang

Wen

Zhao

et al. 2016

Materials Science and Engineering: C

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Section: Introductionmentioning

confidence: 99%

Effect of the addition CNTs on performance of CaP/chitosan/coating deposited on magnesium alloy by electrophoretic deposition

Zhang

Wen

Zhao

et al. 2016

Materials Science and Engineering: C

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“…Coatings made of CNTs provide implants with enhanced bioactive properties and open new possibilities in terms of their biological functionalization. [13][14][15] They can also be further modified to increase the range of titanium biomedical applications.…”

Section: Introductionmentioning

confidence: 99%

Carbon nanotube-based coatings on titanium

et al. 2015

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This paper reports results of the modification of titanium surface with multiwalled carbon nanotubes (CNTs). The Ti samples were covered with CNTs via electrophoretic deposition (EPD) process. Prior to EPD process, CNTs were functionalized by chemical treatment. Mechanical, electrochemical and biological properties of CNT-covered Ti samples were studied and compared to those obtained for unmodified titanium surface. Atomic force microscopy was used to investigate the surface topography. To determine micromechanical characteristics of CNT-covered metallic samples indentation tests were conducted. Throughout electrochemical studies were performed in order to characterize the impact of the coating on the corrosion of titanium substrate. In vitro experiments were conducted using the human osteoblast NHOst cell line. CNT layers shielded titanium from corrosion gave the surface-enhanced biointegrative properties. Cells proliferated better on the modified surface in comparison to unmodified titanium. The deposited layer enhanced cell adhesion and spreading as compared to titanium sample.

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“…The carbon atoms form hexagonal network to form a structure like graphite layer rolled up into a cylinder. 102 CNTs are classified under two categories: single-walled CNTs (SWCNT) consisting of a single cylindrical carbon layer with a diameter in the range of 0.4-2 nm; and multiwalled CNTs (MWCNT) that are usually made from several cylindrical carbon layers. The inner tube has diameter in the range of 1-3 nm and the outer tube in the range of 2-100 nm.…”

Section: Carbon Nanotubes (Cnts) and Theirmentioning

confidence: 99%

Multifunctional Drug Delivery Systems Using Inorganic Nanomaterials: A Review

Sao¹,

Vaish²,

Sinha³

2015

j nanosci nanotechnol

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Targeted drug delivery with controlled rate is vital for therapeutic purpose especially for cancer therapy. Advanced biomaterials with the aid of nanotechnology have evolved as efficient drug delivery systems (DDS), providing a multi-functional platform for simultaneous therapeutic and diagnostic (theranostic) functions. This review discusses current advances in synthesis and applications of inorganic materials such as quantum dots, carbon nanotubes and graphene oxides for drug delivery. The strategies of surface-functionalization of these inorganic materials to render them biocompatible are also reviewed. The advantages and applications of these biomaterials as multi-functional moiety for bio-imaging, drug targeting and delivery have been discussed. The review concludes with discussion on challenges that limits the practical applications of some materials as a drug carrier for therapeutic use. These issues remain to be fully addressed for their maximum utilization for biomedical applications.

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Biomedical investigation of CNT based coatings

Cited by 99 publications

References 86 publications

Effect of the addition CNTs on performance of CaP/chitosan/coating deposited on magnesium alloy by electrophoretic deposition

Effect of the addition CNTs on performance of CaP/chitosan/coating deposited on magnesium alloy by electrophoretic deposition

Carbon nanotube-based coatings on titanium

Multifunctional Drug Delivery Systems Using Inorganic Nanomaterials: A Review

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