Biomedical Biopolymers, their Origin and Evolution in Biomedical Sciences: A Systematic Review

Yadav, Preeti; Yadav, Harsh; Shah, Veena Gowri; Shah, Gaurav; Dhaka, Gaurav

doi:10.7860/jcdr/2015/13907.6565

Cited by 112 publications

(87 citation statements)

References 83 publications

(77 reference statements)

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“…The first aerogels produced were based on inorganic compounds such as silica, but new aerogels have emerged in recent years based on other compounds, such as polysaccharides. These compounds are classified as linear structures of bounded polymeric carbohydrates, which can be obtained from various organisms [8]. This class of biopolymers are allowing to obtain aerogels with properties that stand out from the conventional ones, or with enhanced characteristics like viscoplastic properties, comparing with the brittle nature of silica aerogels [2].…”

Section: Aerogels From Biopolymersmentioning

confidence: 99%

Novel alginate-chitosan aerogel fibres for potential wound healing applications

Batista

Gonçalves

Gaspar

et al. 2020

International Journal of Biological Macromolecules

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A todos aqueles que direta ou indiretamente contribuíram para que esta etapa fosse alcançada, o meu profundo agradecimento. Aos meus orientadores, à Vanessa e ao Frédéric, agradeço-vos por toda a confiança depositada e por todo o conhecimento que me transmitiram. A maneira como ambos pensam a ciência e a vossa capacidade multidisciplinar foram sem dúvida a inspiração que me orientou neste trabalho e me irá orientar para o futuro. À Doutora Ana Matias agradeço a oportunidade de me ter permitido desenvolver este trabalho no grupo Nutraceuticals & Bioactives Process Technology. Deixar também uma palavra de profundo agradecimento a todos os membros deste grupo pela ajuda e companheirismo prestado. Um obrigado especial à Carolina e à Ana Roda pelo vosso apoio. À Doutora Teresa Crespo e a todos os membros dos grupos Food Safety & Microbiology e Membrane Processes pela vossa disponibilidade e boa disposição. Ao Baixinho e ao Pedro, obrigado pela vossa presença e por todas as felicidades e tristezas partilhadas ao longo desta caminhada. Um profundo obrigado aos amigos de longa data Simão, Diogo, Pimentel, Louro, Salomé, Melo e David pelo vosso apoio e compreensão da minha ausência nos momentos mais atribulados. Aos grandes amigos de Coimbra, que mesmo longe se fizeram sentir sempre perto, obrigado Costa, Bibiana, Sandro, Cardoso e Daniel. Aos companheiros "lisboetas", obrigado Sofia, Serafim, Tiago e Adriana, que me fizeram sentir menos deslocado nesta aventura. Por fim, os meus últimos agradecimentos vão para a minha família. Aos meus pais, aos meus avós e ao meu irmão agradeço-vos profundamente por toda a ajuda na concretização desta etapa.

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Section: Aerogels From Biopolymersmentioning

confidence: 99%

Novel alginate-chitosan aerogel fibres for potential wound healing applications

Batista

Gonçalves

Gaspar

et al. 2020

International Journal of Biological Macromolecules

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“…Biopolymers such as chitosan, alginate, fucoidan, hyaluronic acid, etc. are non-toxic, readily available, biodegradable, biocompatible, and non-immunogenic [ 7 , 8 ]. Alginate application in wound dressings is due to its unique properties, such as non-toxicity, biocompatibility, non-immunogenicity, affordability, and high absorption capacity [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

“…However, biopolymers are generally limited by their poor mechanical properties. They are combined with synthetic polymers in order to enhance their mechanical properties and tailored to modify their degradation pattern [ 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

Alginate in Wound Dressings

2018

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Alginate is a biopolymer used in a variety of biomedical applications due to its favourable properties, such as biocompatibility and non-toxicity. It has been particularly attractive in wound healing applications to date. It can be tailored to materials with properties suitable for wound healing. Alginate has been used to prepare different forms of materials for wound dressings, such as hydrogels, films, wafers, foams, nanofibres, and in topical formulations. The wound dressings prepared from alginate are able to absorb excess wound fluid, maintain a physiologically moist environment, and minimize bacterial infections at the wound site. The therapeutic efficacy of these wound dressings is influenced by the ratio of other polymers used in combination with alginate, the nature of cross linkers used, the time of crosslinking, nature of excipients used, the incorporation of nanoparticles, and antibacterial agents. This review provides a comprehensive overview of the different forms of wound dressings containing alginate, in vitro, and in vivo results.

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“…Biopolymers are mainly divided into two types as natural or synthetic/manmade polymers; further, they are divided into subsections depending on their manufacturing process and inherent functional groups. Natural biopolymers are further sub-classified into two types based on the sources, as plant-derived or animal-derived biopolymers; plant-based biopolymers are those which are obtained from plants, trees, or biomass and are called agro-polymers, such as cellulose, starch, hemicellulose, and lignin, among others [27,28]. Cellulose is the most abundantly available polymer in today's world with around 1.5 × 10 12 tons of annual production and is considered an inexhaustible source of biopolymer [29], often extracted from various agricultural and other natural sources [30,31].…”

Section: Microscopic Techniquesmentioning

confidence: 99%

Microscopic Techniques for the Analysis of Micro and Nanostructures of Biopolymers and Their Derivatives

et al. 2020

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Natural biopolymers, a class of materials extracted from renewable sources, is garnering interest due to growing concerns over environmental safety; biopolymers have the advantage of biocompatibility and biodegradability, an imperative requirement. The synthesis of nanoparticles and nanofibers from biopolymers provides a green platform relative to the conventional methods that use hazardous chemicals. However, it is challenging to characterize these nanoparticles and fibers due to the variation in size, shape, and morphology. In order to evaluate these properties, microscopic techniques such as optical microscopy, atomic force microscopy (AFM), and transmission electron microscopy (TEM) are essential. With the advent of new biopolymer systems, it is necessary to obtain insights into the fundamental structures of these systems to determine their structural, physical, and morphological properties, which play a vital role in defining their performance and applications. Microscopic techniques perform a decisive role in revealing intricate details, which assists in the appraisal of microstructure, surface morphology, chemical composition, and interfacial properties. This review highlights the significance of various microscopic techniques incorporating the literature details that help characterize biopolymers and their derivatives.

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Biomedical Biopolymers, their Origin and Evolution in Biomedical Sciences: A Systematic Review

Cited by 112 publications

References 83 publications

Novel alginate-chitosan aerogel fibres for potential wound healing applications

Novel alginate-chitosan aerogel fibres for potential wound healing applications

Alginate in Wound Dressings

Microscopic Techniques for the Analysis of Micro and Nanostructures of Biopolymers and Their Derivatives

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