Biomedical Applications of Additive Manufacturing

Sheoran, Ankita Jaisingh; Chandra, Angesh; Kumar, Harish

doi:10.1007/978-981-15-8704-7_68

Cited by 5 publications

(2 citation statements)

References 29 publications

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“…Bioink for scaffold and implant construction in IJ 3D bioprinting can be made from both natural and synthetic polymers like alginate, calcium chloride solution, bioceramics, polyethylene glycol dimethacrylate (PEGDMA), and bioglass. Bioink viscosity, temperature, and pressure pulse frequency are important factors in IJ 3D bioprinting [ 87 ]. The ink droplets are produced as drop-on-demand (DOD) and continuous methods (CIJ).…”

Section: Suitability Of Am Technologies In 3d Bioprintingmentioning

confidence: 99%

Additive manufacturing for biomedical applications: a review on classification, energy consumption, and its appreciable role since COVID-19 pandemic

et al. 2022

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The exponential rise of healthcare problems like human aging and road traffic accidents have developed an intrinsic challenge to biomedical sectors concerning the arrangement of patient-specific biomedical products. The additively manufactured implants and scaffolds have captured global attention over the last two decades concerning their printing quality and ease of manufacturing. However, the inherent challenges associated with additive manufacturing (AM) technologies, namely process selection, level of complexity, printing speed, resolution, biomaterial choice, and consumed energy, still pose several limitations on their use. Recently, the whole world has faced severe supply chain disruptions of personal protective equipment and basic medical facilities due to a respiratory disease known as the coronavirus (COVID-19). In this regard, local and global AM manufacturers have printed biomedical products to level the supply–demand equation. The potential of AM technologies for biomedical applications before, during, and post-COVID-19 pandemic alongwith its relation to the industry 4.0 (I4.0) concept is discussed herein. Moreover, additive manufacturing technologies are studied in this work concerning their working principle, classification, materials, processing variables, output responses, merits, challenges, and biomedical applications. Different factors affecting the sustainable performance in AM for biomedical applications are discussed with more focus on the comparative examination of consumed energy to determine which process is more sustainable. The recent advancements in the field like 4D printing and 5D printing are useful for the successful implementation of I4.0 to combat any future pandemic scenario. The potential of hybrid printing, multi-materials printing, and printing with smart materials, has been identified as hot research areas to produce scaffolds and implants in regenerative medicine, tissue engineering, and orthopedic implants.

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Section: Suitability Of Am Technologies In 3d Bioprintingmentioning

confidence: 99%

Additive manufacturing for biomedical applications: a review on classification, energy consumption, and its appreciable role since COVID-19 pandemic

et al. 2022

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“…Bioprinting is an extension of traditional 3D printing, functioning on the same core additive manufacturing processes, in which material is appended to the print in cumulative layers to shape 3D products. − Rather than printing with resin or thermoplastics, bioprinters are designed for compatibility with cell-laden bioinks. , Bioprinters utilize various bioinks, including extrusion-based printing using filaments, laser-assisted bioprinting, and inkjet printing of liquid droplets . Through the advances in materials especially polymers, − 3D printing has been established in biomedical applications. ,− Bioprinting has also many tissue engineering and regenerative medicine applications, including, but not limited to, organ-on-a-chip devices for medical and pharmaceutical research − and in vitro models of disease tissues such as tumors for cancer research, human tissue regeneration such as bone, skin, blood vessels, cartilage, and even internal organs to replace those which are damaged or diseased, ,− stem-cell research, − and organoid creation . 3D-bioprinting can enable producing complex 3D structures to mimic the in vivo microenvironment. − With a growing request for scaled-up readily available biomimetic organs and tissues, advances in bioprinting technologies are increasingly imminent and necessary to provide high-throughput, precise construction of cell-laden structures. − …”

Section: Introductionmentioning

confidence: 99%

Bioprinting in Microgravity

Sarabi

Yetisen

2023

ACS Biomater. Sci. Eng.

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Bioprinting as an extension of 3D printing offers capabilities for printing tissues and organs for application in biomedical engineering. Conducting bioprinting in space, where the gravity is zero, can enable new frontiers in tissue engineering. Fabrication of soft tissues, which usually collapse under their own weight, can be accelerated in microgravity conditions as the external forces are eliminated. Furthermore, human colonization in space can be supported by providing critical needs of life and ecosystems by 3D bioprinting without relying on cargos from Earth, e.g., by development and long-term employment of living engineered filters (such as sea sponges−known as critical for initiating and maintaining an ecosystem). This review covers bioprinting methods in microgravity along with providing an analysis on the process of shipping bioprinters to space and presenting a perspective on the prospects of zero-gravity bioprinting.

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