Biomechanics of Keratoconus

Ambrósio, Renato; Esporcatte, Louise Pellegrino Gomes; Salomão, Marcella Q.; Sena, Nelson; Roberts, Cynthia J.

doi:10.1016/b978-0-323-75978-6.00006-6

Cited by 2 publications

(2 citation statements)

References 74 publications

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“…However, the region of maximal stress shifted to regions with greatest curvature instead of greatest thinness in keratoconic eyes. This suggests that the severity of keratoconus parallels the biomechanical cycle of decompensation where there is a repeating cycle of increased strain, stress redistribution, and subsequent focal steepening and thinning ( Ambrósio et al, 2017 , 2023 ; Roberts and Dupps, 2014 ). Notwithstanding corneal thickness and curvature, the severity of biomechanical characteristics of keratoconic groups were stratified using stress-strain index measurements through correlations with age, biomechanically corrected intraocular pressure, and central corneal thickness ( Padmanabhan et al, 2022 ).…”

Section: Stromamentioning

confidence: 95%

Squishy matters – Corneal mechanobiology in health and disease

Thomasy,

Leonard,

Greiner

et al. 2024

Progress in Retinal and Eye Research

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Section: Stromamentioning

confidence: 95%

Squishy matters – Corneal mechanobiology in health and disease

Thomasy,

Leonard,

Greiner

et al. 2024

Progress in Retinal and Eye Research

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“…Regular assessment of corneal biomechanics allows for long-term monitoring, enabling early detection of corneal destabilization and guiding appropriate management strategies. Overall, incorporating corneal biomechanics into clinical practice enhances personalized care for keratoconus patients [132,133].…”

Section: Keratoconusmentioning

confidence: 99%

Corneal biomechanics and diagnostics: a review

Komninou,

Seiler,

Enzmann

2024

Int Ophthalmol

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Purpose Corneal biomechanics is an emerging field and the interest into physical and biological interrelations in the anterior part of the eye has significantly increased during the past years. There are many factors that determine corneal biomechanics such as hormonal fluctuations, hydration and environmental factors. Other factors that can affect the corneas are the age, the intraocular pressure and the central corneal thickness. The purpose of this review is to evaluate the factors affecting corneal biomechanics and the recent advancements in non-destructive, in vivo measurement techniques for early detection and improved management of corneal diseases. Methods Until recently, corneal biomechanics could not be directly assessed in humans and were instead inferred from geometrical cornea analysis and ex vivo biomechanical testing. The current research has made strides in studying and creating non-destructive and contactless techniques to measure the biomechanical properties of the cornea in vivo. Results Research has indicated that altered corneal biomechanics contribute to diseases such as keratoconus and glaucoma. The identification of pathological corneas through the new measurement techniques is imperative for preventing postoperative complications. Conclusions Identification of pathological corneas is crucial for the prevention of postoperative complications. Therefore, a better understanding of corneal biomechanics will lead to earlier diagnosis of ectatic disorders, improve current refractive surgeries and allow for a better postoperative treatment.

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Biomechanics of Keratoconus

Cited by 2 publications

References 74 publications

Squishy matters – Corneal mechanobiology in health and disease

Squishy matters – Corneal mechanobiology in health and disease

Corneal biomechanics and diagnostics: a review

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Biomechanics of Keratoconus

Cited by 2 publications

References 74 publications

Squishy matters – Corneal mechanobiology in health and disease

Squishy matters – Corneal mechanobiology in health and disease

Corneal biomechanics and diagnostics: a review﻿

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Corneal biomechanics and diagnostics: a review