Biomechanical findings in rats undergoing fascial reconstruction with graft materials suggested as an alternative to polypropylene

Konstantinovic, Maja; Ozog, Yves; Spelzini, Federico; Pottier, Cyril; Ridder, Dirk De; Deprest, Jan

doi:10.1002/nau.20755

Cited by 25 publications

(9 citation statements)

References 30 publications

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“…PeriPatch and Tutomesh still were intact, with margin zones appearing to break up slowly. It is unclear how and at what rate this process would have continued after 2 months, but studies evaluating this issue indicate a rapid loss of strength of similar matrices [22]. At autopsy, there was no scaffolding effect for the fibro or myoblasts of any matrix.…”

Section: Discussionmentioning

confidence: 99%

Biologic hernia implants in experimental intraperitoneal onlay mesh plasty repair: the impact of proprietary collagen processing methods and fibrin sealant application on tissue integration

et al. 2011

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Section: Discussionmentioning

confidence: 99%

Biologic hernia implants in experimental intraperitoneal onlay mesh plasty repair: the impact of proprietary collagen processing methods and fibrin sealant application on tissue integration

et al. 2011

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“…The number of animals was chosen from former short term studies with an identical animal model . Data were tested for normality.…”

Section: Methodsmentioning

confidence: 99%

“…The number of animals was chosen from former short term studies with an identical animal model. 23,24 Data were tested for normality. Differences between groups were assessed by Student's t test for paired comparisons and by one way ANOVA with post Dunnet's analysis for multiple group comparison against a designated control group.…”

Section: Statisticsmentioning

confidence: 99%

Electrospun biodegradable microfibers induce new collagen formation in a rat abdominal wall defect model: A possible treatment for pelvic floor repair?

et al. 2017

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Half of the female population over age 50 years will experience pelvic organ prolapse. We suggest a new approach based on tissue engineering principles to functionally reconstruct the anatomical structures of the pelvic floor. The aim of this study is to investigate the mechanical performance and effect on collagen and elastin production of a degradable mesh releasing basic fibroblast growth factor (bFGF). Implantation of biodegradable mesh with or without bFGF in their core has been conducted in 40 rats in an abdominal wall defect model. Samples were explanted after 4, 8, and 24 weeks, and tested for mechanical properties and the composition of connective tissue. The study showed an increase in mRNA expression for collagen-I (p = 0.0060) and collagen-III (p = 0.0086) in the 4 weeks group with bFGF. The difference was equalized at 8 and 24 weeks. No difference was found at any time for protein amount for collagen-I, collagen-III, and fibronectin. The amount of collagen decreased from 4 to 24 weeks but the fraction of collagen increased. The maximal load of the newly formed tissue showed no effect of bFGF at any time. Exclusively, histology showed a limited ingrowth of collagen fibers after 4 weeks with bFGF but signs of elastin fibers were seen at 24 weeks. The investigation showed that a biodegradable mesh promotes tissue formation with a promising strength. The mesh with bFGF did not represent any advantage on either long or short term in comparison to the mesh without bFGF. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 680-688, 2018.

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“…Vaginal hematomas and seromas are also consequences of recently developed urogynecologic techniques. Seromas are seen in sling procedures 34 and insertion of vaginal grafts 35 and meshes 36 . They can develop in patients after posterior vaginal reconstruction of rectoceles or enteroceles with biological grafts.…”

Section: Vaginal Seromas and Hematomasmentioning

confidence: 99%

Evaluation of Vaginal Cysts and Masses by 3‐Dimensional Endovaginal and Endoanal Sonography

Shobeiri

Rostaminia

White

et al. 2013

J of Ultrasound Medicine

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The purpose of this pictorial essay is to describe the utility of 3-dimensional endovaginal and endoanal sonography in the assessment of vulvovaginal cysts and masses. It is accepted that compared with transabdominal pelvic sonography, transvaginal end-fire sonography provides improved resolution for visualization of female reproductive organs with fewer artifacts. To visualize the structures that are located in or lateral to the vaginal canal, side-fire 3-dimensional endovaginal or endoanal sonography can be used. This special technique has the advantage of maintaining the spatial anatomic relationship of any abnormality in the vagina.

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Biomechanical findings in rats undergoing fascial reconstruction with graft materials suggested as an alternative to polypropylene

Cited by 25 publications

References 30 publications

Biologic hernia implants in experimental intraperitoneal onlay mesh plasty repair: the impact of proprietary collagen processing methods and fibrin sealant application on tissue integration

Biologic hernia implants in experimental intraperitoneal onlay mesh plasty repair: the impact of proprietary collagen processing methods and fibrin sealant application on tissue integration

Electrospun biodegradable microfibers induce new collagen formation in a rat abdominal wall defect model: A possible treatment for pelvic floor repair?

Evaluation of Vaginal Cysts and Masses by 3‐Dimensional Endovaginal and Endoanal Sonography

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