Biomaterials for the developing world

Moussy, Francis

doi:10.1002/jbm.a.32866

Cited by 17 publications

(10 citation statements)

References 12 publications

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“…To our knowledge, Moussy's 2010 letter to the editor of JBMR remains the sole discussion of the use of biomaterials in low and middle income countries. 1 Unfortunately, the quote at the top of this article is as true today as it was when it was published. The only other source of note is that from Fatunde and Bhatia that discusses the fundamental economic mismatch between the developed and developing world that hampers the medical device industry, and the potential of corn and soy derived biopolymers for the locally sourced fabrication of biomaterials.…”

Section: Original Articlementioning

confidence: 99%

“…To our knowledge, Moussy's 2010 letter to the editor of JBMR remains the sole discussion of the use of biomaterials in low and middle income countries . Unfortunately, the quote at the top of this article is as true today as it was when it was published.…”

Section: Introductionmentioning

confidence: 99%

“…It is well documented that medical instrumentation donated to hospitals and clinics across East Africa frequently fall into disrepair because of lack of parts, funds, or expertise to repair and/or replace them . Access to implantable medical devices, and surgical supplies is also inadequate, often leading to “making do” with what is available or simply postponing or canceling procedures . Addressing these and similar issues is precisely why Makerere University in Kampala, Uganda partnered with its teaching hospital Mulago National Referral Hospital in 2011 to start the first degree‐granting program in Biomedical Engineering (BME) in sub‐Saharan Africa.…”

Section: Introductionmentioning

confidence: 99%

“…[7][8][9] Access to implantable medical devices, and surgical supplies is also inadequate, often leading to "making do" with what is available or simply postponing or canceling procedures. 1 Addressing these and similar issues is precisely why Makerere University in Kampala, Uganda partnered with its teaching hospital Mulago National Referral Hospital in 2011 to start the first degree-granting program in Biomedical Engineering (BME) in sub-Saharan Africa. The goal of this program is to train the homegrown talent that will become the leaders in BME science and engineering in the commercial and academic sectors of Uganda.…”

Section: Introductionmentioning

confidence: 99%

“…

It is a sad fact that during [my] 20 years working on biomaterials, the needs of the poorest populations were almost never mentioned. The biomaterials community is insulated from these discussions [that] focuses solely on the developed world Francis Moussy, Director UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases …”

mentioning

confidence: 99%

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Biomaterials use in Mulago National Referral Hospital in Kampala, Uganda: Access and affordability

Bakwatanisa

Enywaku

Kiwanuka

et al. 2015

J Biomedical Materials Res

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Students in Biomaterials BBE3102 at Makerere University in Kampala, Uganda were assigned semester long group projects in the first semester of the 2014-15 academic year to determine the biomaterials type and usage in Mulago National Referral Hospital, which is emblematic of large public hospitals across East Africa. Information gathering was conducted through student interviews with Mulago physicians because there were no archival records. The students divided themselves into seven project groups covering biomaterials use in the areas of wound closure, dental and oral surgery, cardiology, burn care, bone repair, ophthalmology and total joint replacement. As in the developed world, the majority of biomaterials used in Mulago are basic wound closure materials, dental materials, and bone fixation materials, all of which are comparatively inexpensive, easy to store, and readily available from either the government or local suppliers; however, there were significant issues with the implant supply chain, affordability, and patient compliance and follow-up in cases where specialty expertise and expensive implants were employed.

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Section: Original Articlementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…

mentioning

confidence: 99%

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Biomaterials use in Mulago National Referral Hospital in Kampala, Uganda: Access and affordability

Bakwatanisa

Enywaku

Kiwanuka

et al. 2015

J Biomedical Materials Res

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Hydroxyapatite–Graphene as Advanced Bioceramic Composites for Orthopedic Applications

Basirun

Baradaran

2016

Advanced 2D Materials

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Functions and applications of metallic and metallic oxide nanoparticles in orthopedic implants and scaffolds

2020

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Bone defects and diseases are devastating, and can lead to severe functional deficits or even permanent disability. Nevertheless, orthopedic implants and scaffolds can facilitate the growth of incipient bone and help us to treat bone defects and diseases. Currently, a wide range of biomaterials with distinct biocompatibility, biodegradability, porosity, and mechanical strength is used in bone-related research. However, most orthopedic implants and scaffolds have certain limitations and diverse complications, such as limited corrosion resistance, low cell proliferation, and bacterial adhesion. With recent advancements in materials science and nanotechnology, metallic and metallic oxide nanoparticles have become the subject of significant interest as they offer an ample variety of options to resolve the existing problems in the orthopedic industry. More importantly, these nanoparticles possess unique physicochemical and mechanical properties not found in conventional materials, and can be incorporated into orthopedic implants and scaffolds to enhance their antimicrobial ability, bioactive molecular delivery, mechanical strength, osteointegration, and cell labeling and imaging. However, many metallic and metallic oxide nanoparticles can also be toxic to nearby cells and tissues. This review article will discuss the applications and functions of metallic and metallic oxide nanoparticles in orthopedic implants and bone tissue engineering.

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Biomaterials for the developing world

Cited by 17 publications

References 12 publications

Biomaterials use in Mulago National Referral Hospital in Kampala, Uganda: Access and affordability

Biomaterials use in Mulago National Referral Hospital in Kampala, Uganda: Access and affordability

Hydroxyapatite–Graphene as Advanced Bioceramic Composites for Orthopedic Applications

Functions and applications of metallic and metallic oxide nanoparticles in orthopedic implants and scaffolds

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