Biomarkers associated with obstructive sleep apnea and morbidities: a scoping review

Building Evidence Implicating Novel Cardiovascular Biomarkers in Obstructive Sleep Apnea

“…5 It is involved with transport of vesicles from the Golgi apparatus to the endoplasmic reticulum and is involved with the processing, activity, and recycling of low-density lipoprotein receptors. Unlike many prior studies that have not effectively elucidated morbidity biomarkers in OSA, 6 the current work clearly demonstrates a significant association of COPE-Ab and cardiovascular disease and stroke, suggesting a possible beneficial role in risk stratification to identify those with OSA most likely to have cardiovascular risk.…”

Sleep apnea classification based on respiration signals by using ensemble methods

“…Sleep apnea defined as the disruption of breathing for more than 10 s in adults [2]. Daytime sleepiness, impaired concentration, depression, memory loss, tiredness and early morning headaches can be observed in SAS patients [3][4][5][6]. Besides, untreated and undiagnosed sleep apnea can relate to heart disease like hypertension, myocardial infarction and stroke [7][8][9].Sleep disorders have become important factors that adversely affect individuals' quality of life and society as a whole [10].…”

Sleep disordered breathing in childhood

“…MRP-8/14 was increased in children with obesity and OSA. Considering the physiological importance of neurotransmitters as signalling molecules in the nervous system and the potential alterations that may develop in the context of OSA, urinary neurotransmitters may also provide a good tool for screening OSA related to cognitive morbidity in children [24].…”