Biomarkers and Bacteria Around Implants and Natural Teeth in the Same Individuals

Abstract

There were many similarities but, crucially, some differences in biomarker levels (IL-1β and sRANKL) and bacterial species between peri-implant and periodontal sites in the same individuals, suggesting similar pathogenic mechanisms.

Peri-implant clinical and radiographic status and whole salivary cotinine levels among cigarette and waterpipe smokers and never-smokers

“…These are possible explanations for the similarity in PI, PD, and CBL among individuals in Groups 1 and 2. Among participants in Group 3, the most likely reason for the occurrence of peri-implantitis appeared to be poor oral hygiene maintenance, as dental plaque harbors pathogenic microbes (such as Porphyromonas gingivalis and Treponema denticola) that are associated with oral soft tissues inflammation and alveolar bone loss around teeth and implants (30,31).…”

Assessment of interleukin‐1β, interleukin‐6, and tumor necrosis factor‐Α levels in the peri‐implant sulcular fluid among waterpipe (narghile) smokers and never‐smokers with peri‐implantitis

“…In the present study nearly 72% individuals in group‐2 reported to brush their teeth once daily and none of the individuals in either group reported to have ever used a dental floss. Studies have reported that a poor plaque control is associated with an increased frequency of pathogenic microbes (such as Prevotella intermedia , Treponema denticola , and Aggregatibacter actinomycetemcomitans ) that have been associated with the etiology of periodontitis as well as peri‐implantitis. It is also notable that although the number of individuals in group‐1 (approximately 78%) that reported to brush their teeth once daily was similar to those in group‐2 (approximately 72%), peri‐implant PPD and CBL were significantly higher among individuals in group‐1 than group‐2.…”

Intraoral versus extraoral cementation of implant‐supported single crowns: Clinical, biomarker, and microbiological comparisons

“…Published studies mostly suggest that biomarker and microbiological data are similar around natural teeth and intraosseous dental implants as long as the clinical health state is similar . A recent study by Gürlek and colleagues also stated that differences in bacterial species in the same individuals were evident. The present study revealed similar findings in the PICF and GCF samples.…”

“…Inflammation affecting the peri‐implant tissues causes mucositis and peri‐implantitis via similar inflammatory mechanisms acting in the pathogenesis of gingivitis and periodontitis. There are studies reporting similar content of the pathogenic bacteria in the biofilm around dental implants and natural teeth while differences in bacterial species in the same individuals were demonstrated recently suggesting distinct pathogenic mechanisms . It is also shown that presence of Aggregatibacter actinomycetemcomitans , Prevotella intermedia , Porphyromonas gingivalis , Treponema denticola , and Fusobacterium nucleatum at the implant sulcus was affected by the presence or absence of these microorganisms in the gingival crevice of adjacent teeth rather than other sites in the dentition …”